RESOURCE CORE 3: BIOSTATISTICS AND DATA MANAGEMENT CORE

资源核心 3：生物统计学和数据管理核心

• 批准号: 8206035
• 负责人: Michael J Daniels
• 金额: $ 9.94万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8206035
• 关键词: Adherence; Aging; American; Attention; Award; Biological; Biological Markers; Biometry; Caring; Clinical; Clinical Research; Clinical Trials Database; Communities; Computer software; Computers; Consult; Controlled Study; Data; Data Analyses; Data Base Management; Data Collection; Data Coordinating Center; Databases; Development; Discipline; Elderly; Ensure; Epidemiology; Faculty; Florida; Funding; Future; Goals; Health Services Research; Human Resources; Internet; Leadership; Manuscripts; Measurement; Measures; Metabolism; Methodology; Methods; Mission; Monitor; Online Systems; Outcome; Outcome Measure; Phase; Pilot Projects; Preparation; Prevention therapy; Procedures; Process; Protocols documentation; Publications; Qualifying; Quality Control; Quality of life; Randomized; Recruitment Activity; Registries; Research; Research Design; Research Methodology; Research Personnel; Resources; Risk; Risk Factors; Sample Size; Sampling; Scheme; Scientist; Selection Bias; Services; Site; Source; Statistical Methods; System; Testing; Time; Training; Universities; Update; Work; career development; computer network; computer program; computerized data processing; data management; database design; design; disability; interest; intervention effect; longitudinal analysis; primary outcome; research and development; sarcopenia

The Biostatistics and Data Management Core (RC3) is one of four resource cores in the OAIC at the University of Florida. The mission ofthe UF OAIC is (1) to assess the risk factors and better understand the biological mechanisms of physical disability in older adults, (2) to develop and test effective prevention therapies, and (3) to educate and train new investigators in research on aging and disability, while developing their leadership qualities. The Biostatistics and Data Management Core is a key cog in the interaction between scientists from many disciplines to accomplish this mission. The core functions as both a data analysis resource and as a data coordinating center, involved in constructing data collection forms and managing the data (including quality control) for the studies conducted within the OAIC. In this capacity, the core maintains and updates the registry for the Recruitment, Adherence, and Retention Core (RC4) and tracks all research conducted within the OAIC with a web tracking system. The core is involved in all phases of these studies including initial study design and sample size calculations pre-proposal, randomization, and state-of-the-art statistical analyses once the data are completed. For study designs and data for which currently methodology is lacking, the core has the expertise to develop new state of the art methodology to perform correct and appropriate analyses of data collected in the Center. The Biostatistics and Data Management Core also is involved in preparation of manuscripts for dissemination within the research community. Finally, the Core serves as a key resource to the Junior Scholars of the Research Career Development Core (RCDC), providing consulting services and periodic special interest training topics, such as research methods, power analysis, analysis of incomplete data, principles of data management, and analysis of longitudinal data.

生物统计和数据管理核心 (RC3) 是佛罗里达大学 OAIC 的四个资源核心之一。佛罗里达大学 OAIC 的使命是 (1) 评估老年人身体残疾的风险因素并更好地了解其生物学机制，(2) 开发和测试有效的预防疗法，以及 (3) 教育和培训老龄化和残疾研究的新研究者，同时培养他们的领导素质。生物统计和数据管理核心是来自多个学科的科学家之间互动以完成这一使命的关键齿轮。核心功能既作为数据分析资源又作为数据 协调中心，参与 OAIC 内进行的研究的数据收集表格的构建和数据管理（包括质量控制）。以此身份，该核心维护和更新招募、遵守和保留核心 (RC4) 的注册表，并使用网络跟踪系统跟踪 OAIC 内进行的所有研究。核心涉及这些研究的所有阶段，包括初始研究设计和样本量计算、建议前、随机化和数据完成后最先进的统计分析。对于目前缺乏方法的研究设计和数据，核心拥有开发新的最先进方法的专业知识，以便对中心收集的数据进行正确和适当的分析。生物统计和数据管理核心还参与准备在研究界传播的手稿。最后，核心作为研究职业发展核心（RCDC）的初级学者的关键资源，提供咨询服务和定期特殊兴趣培训主题，例如研究方法、功效分析、不完整数据分析、数据管理原理，以及纵向数据分析。