NRSA Training Core

NRSA 培训核心

• 批准号: 9314020
• 负责人: TIMOTHY De Ver DYE
• 金额: $ 51.15万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-15 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9314020
• 关键词: Academic support; Address; Area; Award; Big Data; Bioinformatics; Biological Markers; Clinical; Clinical Research; Clinical Sciences; Communities; Creativeness; Data Analytics; Data Science; Development; Discipline; Doctor of Philosophy; Education; Electronic Health Record; Evaluation; Evidence based practice; Fellowship; Genotype; Goals; Health Care Reform; Healthcare; Infection; Institutes; Institution; Interdisciplinary Study; Learning; Link; Medical; Medical Education; Mentors; Methods; Minority-Serving Institution; Modeling; National Research Service Awards; Phenotype; Physicians; Population; Postdoctoral Fellow; Recording of previous events; Research; Research Personnel; Research Training; Role; Science; Scientist; Structure; Students; TNFSF15 gene; Training; Training Programs; Training Support; Translational Research; Universities; Vision; base; biopsychosocial; experience; flexibility; health care delivery; improved; innovation; multidisciplinary; novel; personalized medicine; population health; pre-doctoral; precision medicine; programs; tool; training opportunity

The University of Rochester (UR) has a decades-long distinguished history in innovative clinical research education, enhanced substantially since 2006 with the establishment and focus of the University of Rochester Clinical and Translational Science Institute (UR-CTSI). Building historically on the groundbreaking concept of medical education based on the biopsychosocial model starting in the 1940s with Engel and Romano, the UR has continued to create paradigm-shifting educational reform integrating research and systematic evaluation with problem-based medical education, community engagement and population health, and mentored field experience. This culture of creativity and innovation in pre-doctoral research training supported through prior TL1 awards is embodied by an institutional focus on research training from molecules to populations. Through this and other means, the UR-CTSI has created an institution-wide focal point for multidisciplinary research training. Further, UR-TL1-supported students in the 50+ year-old UR MD/PhD training program (Medical Scientist Training Program (MSTP)) have taken advantage of the UR-CTSI's PhD program in Translational Biomedical Science and other multidisciplinary graduate training options. In addition, the UR-TL1-supported Academic Research Track (ART) further provides a pipeline of clinical and translational research-prepared academic physicians through a comprehensive research training and mentoring experience. Predoctoral training is a priority within Rochester's CTSI, is well-integrated, and has successfully generated productive, employed clinical researchers, both within and outside of academics. The vision for the UR-TL1 in the next era of UR-CTSI is inspired by several critical developments in the healthcare and institutional landscape of Rochester and the US more broadly, namely: 1) Implementation of national health care reform prioritizing evidence-based practice and population health, 2) rapid emergence of data science and “Big Data” analytic opportunities and methodological approaches to healthcare and population health, and 3) emergence of precision medicine research and healthcare delivery using phenotype- genotype and biomarker-informed science. The goals for the coming five years include 1) to grow a pipeline of clinical and translational researchers able to address new and emerging scientific and methodological domains; 2) to enhance experiential and didactic learning through new training opportunities and partnerships that emphasize team science; 3) to stimulate creative and novel population health research that involves leveraging new tools and methods through establishing a University-wide Post-Doctoral Fellowship in Population Health; and 4) to rigorously evaluate the role of the UR-TL1 Training Program on the development of the clinical and translational research pipeline and disseminate learnings from the training program.

罗切斯特大学（UR）在创新临床研究中拥有数十年的杰出历史 自2006年以来，随着罗切斯特大学的建立和重点，教育大大增强 临床和转化科学研究所（UR-CTSI）。历史上建立在开创性的概念上 从1940年代开始，基于生物心理社会模型的医学教育与UR恩格尔和罗曼诺开始 继续创建范式转移教育改革，整合研究和系统评估 通过基于问题的医学教育，社区参与和人口健康，并修改了领域 经验。通过先验支持的博士前研究培训中的这种创造力和创新文化 TL1奖项由机构重点放在分子到人群的研究培训的机构中所体现。通过 这和其他方式，UR-CTSI为多学科研究创建了一个范围的机构焦点 训练。此外，在50岁以上的UR MD/PhD培训计划中，UR-TL1支持的学生（医疗 科学家培训计划（MSTP））利用了UR-CTSI的翻译博士学位计划 生物医学科学和其他多学科研究生培训选择。另外，UR-TL1支持 学术研究轨道（ART）进一步提供了临床和翻译的精心准备的管道 学术医师通过全面的研究培训和心理经验。主肠道 培训是罗切斯特CTSI的优先事项，是整合的，并且已经成功生成的产品， 在学术界内外，受雇的临床研究人员。 UR-TL1在下一个UR-CTSI时代的愿景受到了几个关键发展的启发 罗切斯特和美国的医疗保健和机构格局更广泛，即：1）实施 国家卫生保健改革优先考虑循证实践和人口健康，2） 数据科学和“大数据”分析机会以及医疗保健和方法论方法 人口健康以及3）使用表型出现精密医学研究和医疗保健提供 - 基因型和生物标志物信息科学。未来五年的目标包括1） 临床和翻译的研究人员可以解决新的和新兴的科学和方法论 域； 2）通过新的培训机会和伙伴关系来增强专家和教学学习 这强调了团队科学； 3）刺激涉及的创造性和新颖的人口健康研究 通过建立大学范围的博士后研究金来利用新的工具和方法 人口健康； 4）严格评估UR-TL1培训计划在开发中的作用 临床和翻译的研究管道，并从培训计划中传播学习。