RESEARCH METHODS CORE

研究方法核心

• 批准号: 8921255
• 负责人: Mary Amanda Dew
• 金额: $ 39.63万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2017-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8921255
• 关键词: Address; Advanced Development; Area; Biometry; Butter; Caring; Cognitive; Communities; Community Practice; Comorbidity; Data Analyses; Development; Doctor of Philosophy; Economics; Effectiveness; Elderly; Electronics; Evaluation; Generations; Goals; Individual; Intervention; Investigation; Measurement; Measures; Mental Depression; Mental Health; Methodology; Methods; Modeling; Mood Disorders; Needs Assessment; Outcome; Pain; Patient Care; Pattern; Prevention Research; Prevention trial; Preventive Intervention; Primary Health Care; Property; Provider; Psychometrics; Research; Research Design; Research Infrastructure; Research Methodology; Research Personnel; Resources; Respondent; Risk; Risk Assessment; Risk Factors; Science; Statistical Models; Subgroup; Symptoms; Testing; Training; Ursidae Family; Vision; Work; base; computerized; depression prevention; depressive symptoms; disability; effective intervention; effectiveness research; effectiveness trial; forging; functional disability; functional status; geriatric depression; high risk; indicated prevention; innovation; medical specialties; meetings; mental age; method development; migration; multidisciplinary; operation; prevention effectiveness trial; response; selective prevention; tool

The Overview to our Center application elucidates our vision of how and why late life depression prevention effectiveness research must be advanced in the next five years. The Research Methods Core (RMC) will provide the infrastructure to support the development of innovative methodologies to address the research issues and goals that emerge from this vision. Thus, the RMC will forge methodologic bridges between the Center's overall vision, on the one hand, and the research to be accomplished in order to meet it. An equally important RMC goal is to contribute to progress of the science of prevention research�at both the level of effectiveness assessment and the level of sustainability and transfer�within the mental health and aging research and practice communities. The RMC will accomplish these objectives through the efforts of a unified, multidisciplinary team of methodologists. This team will be organized into three subgroups (Units) with expertise brought to bear on specific methodologic areas: 1. The Assessment of Risk and Intervention Outcomes Unit will focus on the development and application of a new generation of electronic assessment strategies for measuring both risk factors and intervention outcomes in depression prevention trials. Domains of focus include the measurement of depressive symptoms and symptoms of other comorbidities; cognitive status; and overall functional status and disability. 2. The Research Design and Biostatistics Unit will focus on the development and application of models to characterize dynamic patterns of risk factors and transition between states/levels of depression, as well as on the development of methods to promote the efficient analysis of data from response-adaptive allocation research designs. 3. The Implementation. Portabilitv. Sustainabilitv and Migration Unit will focus on the application of tools to promote intervention dissemination and sustainability, with an emphasis on the use of methods that better characterize the content and delivery of interventions, as well as determine interventions' economic feasibility. Moreover, this Unit will work on the development and initial testing of strategies to migrate traditional interventions to electronic delivery modes. Within each RMC Unit, work will be pursued at two levels of function: (a) direct research investigation of new tools and approaches, utilizing the Principal Research Core projects as critical platforms for this work and (b) dissemination and training efforts both within and beyond the Center, involving close liaisons with the Operations Core so that new RMC tools and approaches can be smoothly transferred to the Operations Core 'loolbox" of Center resources and strategies.

我们中心应用程序的概述阐明了我们在未来五年内必须提出如何以及为何预防后期预防效果研究的愿景。研究方法核心（RMC）将提供基础架构，以支持创新方法的开发，以解决从该愿景中产生的研究问题和目标。这就是RMC一方面将在中心的整体愿景和为了满足它来实现的研究之间构建方法论桥。一个 同样重要的RMC目标是在有效性评估水平以及心理健康，老龄化研究与实践社区内的预防科学研究水平以及可持续性和转移水平上为预防科学研究的进步做出贡献。 RMC将通过统一的，多学科的方法论家团队的努力来实现这些目标。该团队将分为三个子组（单位） 具有在特定方法论领域的专业知识： 1。对风险和干预结果的评估单位将着重于新一代电子评估策略的开发和应用，以衡量抑郁症预防试验中的风险因素和干预结果。重点领域包括测量抑郁症状和其他合并症的症状；认知状况；以及整体功能状况和残疾。 2。研究设计和生物统计学单元将重点介绍模型的开发和应用，以表征风险因素的动态模式和状态/抑郁级别之间的过渡，以及开发方法，以促进从反应自适应分配研究设计中对数据有效分析的有效分析。 3。实施。 Portabilitv。可持续性和移民部门将专注于应用工具来促进干预传播和可持续性，并着重于使用更好地表征干预措施的内容和提供的方法，并确定干预措施的经济可行性。此外，该单元将致力于开发和初步测试策略，以将传统干预措施迁移到电子交付模式。 Within each RMC Unit, work will be pursued at two levels of function: (a) direct research investment of new tools and approaches, using the Principal Research Core projects as critical platforms for this work and (b) dissemination and training efforts both within and beyond the Center, involved close liaisons with the Operations Core so that new RMC tools and approaches can be smoothly transferred to the Operations Core 'loolbox" of Center resources and strategies.