CENTER FOR SKELETAL RESEARCH

骨骼研究中心

• 批准号: 8853820
• 负责人: HENRY M. KRONENBERG
• 金额: $ 69.6万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-06-01 至 2019-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8853820
• 关键词: CENTER; SKELETAL; RESEARCH

DESCRIPTION (provided by applicant): The overall goal of the Center for Skeletal Research is to foster Interdisciplinary and collaborative work that leads to a deeper understanding of skeletal biology, in a way that can lead to new ways of diagnosing and treating skeletal diseases. The Center will build upon and expand a community of bone scientists in the Endocrine Unit and other Units at the Massachusetts General Hospital, the Harvard School of Dental Medicine, and other Harvard-associated departments and institutions. This group has already defined itself through a network of collaborations and a monthly seminar series sponsored jointly by the MGH Endocrine Unit and the Harvard School of Dental Medicine, and includes bone scientists from multiple Harvard institutions. These scientists are diverse, including clinical investigators and laboratory investigators using a broad array of approaches from multiple disciplines. The mechanisms that the Center will use to accomplish its goal include Core Facilities, a Pilot and Feasibility Grant Program, and a seminar series. The Cores will include a Skeletal Phenotyping Core and a Bone Cells and Signaling Core. These Cores will emphasize the development of new techniques that can drive the science of Center investigators, as well as the provision of expert and efficient service. The goal of the Pilot and Feasibility Grant Program will be to allow young investigators to develop sufficient data to obtain their own grants; in that context, a vigorous mentoring program will complement the funding. The seminar series will foster collaboration and communication among Center scientists. Young investigators will present current data in some sessions, while others will bring in distinguished bone scientists from outside of Boston to enrich the environment. This series will also include presentations by Core Directors that explain the techniques used in the Cores and will provide a forum for feedback by Center investigators that will include suggestions for novel Core services. An Administrative Core will assure effective functioning of these activities through regular meetings of Core Directors that, four times a year, will also involve meeting with an Advisory Committee made up of senior investigators within the Center, as well as investigators from elsewhere with relevant experience leading similar programs. The Center will be committed to sharing its innovations with the broader community of bone scientists across the country.

描述（由申请人提供）：骨骼研究中心的总体目标是培养跨学科和协作工作，从而使人们对骨骼生物学有更深入的了解，从而可以导致新的诊断和治疗骨骼疾病的方法。该中心将在马萨诸塞州综合医院，哈佛大学牙科医学院以及其他与哈佛大学相关的部门和机构的内分泌部门和其他部门中建立并扩展一个骨科学家社区。该小组已经通过MGH内分泌部门和哈佛大学牙科医学学院共同赞助的合作网络和每月的研讨会系列来定义自己，其中包括来自哈佛大学多个机构的骨科学家。这些科学家是多种多样的，包括临床研究人员和实验室研究人员使用多种学科的广泛方法。该中心将用来实现其目标的机制包括核心设施，试点和可行性赠款计划以及研讨会系列。核心将包括骨骼表型核心和骨细胞和信号芯。这些核心将强调开发可以推动中心研究人员科学的新技术，以及提供专家和高效服务。飞行员和可行性赠款计划的目标是允许年轻的调查人员制定足够的数据以获得 他们自己的赠款；在这种情况下，一个有力的指导计划将补充资金。研讨会系列将促进中心科学家之间的合作和沟通。年轻的研究人员将在某些会话中介绍当前的数据，而其他研究人员将引入来自波士顿以外的杰出骨科学家，以丰富环境。该系列还将包括核心主管的演讲，这些核心主管解释了核心中使用的技术，并将为中心调查人员提供一个反馈论坛，其中包括新型核心服务的建议。行政核心将通过核心董事的定期会议确保这些活动有效地运作，该会议每年四次还涉及与该中心高级调查员组成的咨询委员会会议，以及来自其他地方的调查人员，具有相关经验的领先经验类似的程序。该中心将致力于与全国各地的骨科学家社区分享其创新。