2015 Cellular and Molecular Mechanisms of Toxicology Gordon Research Conference & Gordon Research Seminar

2015毒理学细胞和分子机制戈登研究会议

• 批准号: 8895591
• 负责人: Dana Dolinoy
• 金额: $ 0.8万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-05-01 至 2016-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8895591
• 关键词: Academia; Academy; Area; Biochemical; Biological Models; Birth; Chemical Injury; Chemicals; Collaborations; Collection; Complex; Computer Simulation; Data; Decision Making; Development; Discipline; Disease; Education; Emerging Technologies; Environment; Environmental Exposure; Epigenetic Process; Event; Fostering; Future; Gender; Generations; Genomics; Goals; Government; Health; Human; Industry; International; Link; Malignant Neoplasms; Mentors; Microfluidics; Molecular; Molecular Toxicology; Nationalities; New Hampshire; Obesity; Organ Model; Outcome; Pathogenesis; Pathway interactions; Pharmacologic Substance; Poison; Policy Making; Postdoctoral Fellow; Printing; Regulation; Research; Research Personnel; Risk; Risk Assessment; Role; Safety; Science; Scientist; Senior Scientist; Staging; Stem cells; Systems Biology; Techniques; Technology; Time; Toxic effect; Toxicogenetics; Toxicology; Translations; Work; base; carcinogenesis; career; collaborative environment; educational atmosphere; experience; forging; graduate student; human disease; in vitro Model; in vivo; in vivo Model; innovation; interest; meetings; microbiome; novel; posters; programs; public health relevance; rapid technique; symposium; three-dimensional modeling; undergraduate student

 DESCRIPTION (provided by applicant): Research in basic molecular toxicology continues to underpin key innovations and advances in environmental, pharmaceutical, and industrial sciences by striving to elucidate the cellular, biochemical, and genomic mechanisms of action of toxic substances. The pace of national and international regulation of environmental and pharmaceutical exposures is rapid and methods to assess the risk of substances to human health are continually advancing. For the 2015 Gordon Research Conference (GRC) in Cellular & Molecular Mechanisms of Toxicity (CMMT), we are focusing on "Mechanistic Toxicology: The Path Forward," with the goal of incorporating research on the mechanistic basis of disease into risk decision and policymaking. The topics covered are varied and of great appeal to a broad audience of scientists with interest in toxicology. Emerging technologies including computational and 3D modeling as well as in vivo and systems biology approaches to assessing risk to human disease will be highlighted. The microbiome, the inflammasome, epigenetics, carcinogenesis, and stem cells in toxicological research are among the topics that will be highlighted at the conference. The Conference will bring together an interdisciplinary collection of investigators who are at the forefront of their field, and will provide opportunities for junior scientists and graduate and undergraduate students to present their work in poster and platform format and exchange ideas with leaders in the field. The collegial atmosphere of this Conference, with programmed discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings, provides an avenue for scientists from different disciplines to network and promotes trans-disciplinary collaborations in the various research areas represented. For the second time, a Gordon Research Seminar (GRS) will be held in conjunction with this conference. The 2015 GRS on "Advanced in Vitro Models in Mechanistic Toxicology" will highlight recent advancements in the development of complex in vitro models, and their utility in toxicology research and safety assessment. This is a unique forum for graduate students, postdoctoral fellows, and other scientists with comparable levels of experience and education to network and present and exchange new data and cutting edge ideas.

 描述（由申请人提供）：通过努力阐明有毒物质的细胞、生化和基因组作用机制，基础分子毒理学研究继续支撑环境、制药和工业科学的关键创新和进步。国际上对环境和药物暴露的监管非常迅速，评估物质对人类健康风险的方法也在不断进步，2015 年戈登研究会议 (GRC) 的细胞和分子机制。毒性（CMMT），我们的重点是“机械毒理学：前进的道路”，目标是将疾病的机械基础研究纳入风险决策和政策制定中，涵盖的主题多种多样，对广大受众具有很大的吸引力。对毒理学感兴趣的科学家将重点关注评估人类疾病风险的计算和 3D 建模以及体内和系统生物学方法。毒理学研究中的干细胞和干细胞是会议将重点讨论的主题之一，会议将汇集处于各自领域前沿的跨学科研究人员，并将为初级科学家以及研究生和本科生提供机会。以海报和平台的形式展示他们的工作，并与该领域的领导者交流想法 本次会议的学术氛围，包括有计划的讨论会议以及下午和晚上的非正式聚会的机会，为来自不同学科的科学家提供了一个交流的平台。网络并促进跨学科戈登研究研讨会 (GRS) 将与本次会议同时举行，主题是“机械毒理学先进体外模型”，这将是第二次。这是一个独特的论坛，为研究生、博士后研究员和其他具有相当经验和教育水平的科学家提供网络并展示和交换新数据和信息。前沿的想法。