WHCOHH: Harmful algal bloom dynamics and epigenetic mechanism of toxin action

WHCOHH：有害藻华动态和毒素作用的表观遗传机制

• 批准号: 9059852
• 负责人: JOHN J STEGEMAN
• 金额: $ 2.39万
• 依托单位: WOODS HOLE OCEANOGRAPHIC INSTITUTION
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-24 至 2017-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9059852
• 关键词: Address; Adult; Advisory Committees; Affect; Archives; Area; Biological Models; Communication; Community Health Education; Community Outreach; Data; Development; Dinophyceae; Ensure; Epigenetic Process; Evaluation; Exposure to; Fostering; Goals; Grant; Information Dissemination; Life; Link; Maine; Marine Toxins; Mission; Modeling; Monitor; National Institute of Environmental Health Sciences; Neurotoxins; Organism; Performance; Physiological; Policies; Population Dynamics; Process; Production; Public Health; Reporting; Research; Research Personnel; Resources; Risk; Sampling; Societies; Structure; System; Technology; Toxin; harmful algal blooms; improved; insight; meetings; member; novel; predictive modeling; programs; public health relevance; toxicant; web page

DESCRIPTION (provided by applicant) This Program Project application will employ novel remote sampling technologies to achieve new insights into the population dynamics of known and emerging HAB threats, and to address critical mechanisms of toxin action, linking developmental exposures to adult consequences. The Center will be overseen and guided by the Director and Deputy Director. The aims of the Administrative Core are to: 1) Facilitate communication, planning, integration and interaction among Center members, so that the goals and scientific objectives of the Center are achieved. 2) Provide and maintain an administrative structure to oversee and monitor the financial aspects of the Center, including grants management. 3) Establish a structure that will support effective communication and planning with contribution from all Center investigators, through an Internal Advisory Committee. 4) Establish an External Advisory Committee, which will review the Center programs and advise the Director and Deputy Director. 5) Implement evaluation mechanisms, utilizing both Internal and External Advisory Committees. 6) Establish and maintain public and private web pages for the dissemination of information and for data transfer and communication 7) Pursue interactions between the WHCOHH and other OHH Centers, as well as with other EHS Centers, in order to expand the reach and impact of the Center, and potentially to engage collaborators on research issues relevant to the Center mission and themes. 8) Encourage the involvement of Center investigators in community outreach and education efforts. 9) Prepare and deliver the required reports to the NSF and the NIEHS. 10) Organize COHH meetings as required. 11) Ensure compliance with data submission and archiving policies.

描述（由申请人提供） 该计划项目应用程序将采用新颖的远程抽样技术来实现对已知和新兴HAB威胁的人群动态的新见解，并解决毒素作用的关键机制，从而将发育暴露与​​成人后果联系起来。该中心将由董事兼副主任监督和指导。行政核心的目的是：1）促进中心成员之间的沟通，计划，整合和互动，以便实现该中心的目标和科学目标。 2）提供和维护行政结构，以监督和监视包括赠款管理在内的中心的财务方面。 3）建立一种结构，将通过内部咨询委员会所有中心调查员的贡献，以支持有效的沟通和计划。 4）建立一个外部咨询委员会，该委员会将审查中心计划并为董事和副主任提供建议。 5）使用内部和外部咨询委员会实施评估机制。 6）建立并维护公共和私人网页以传播信息以及数据传输和通信7）追求WhoCHH与其他OHH中心以及与其他EHS中心之间的互动，以扩大中心的影响力和影响，并有可能使合作者在与中心任务和主人中有关的研究问题吸引合作者。 8）鼓励中心调查人员参与社区外展和教育工作。 9）准备并向NSF和NIEHS准备所需的报告。 10）根据需要组织COHH会议。 11）确保遵守数据提交和归档政策。