UT southwestern O'Brien Kidney Research Core Center

德克萨斯大学西南奥布莱恩肾脏研究核心中心

• 批准号: 8912182
• 负责人: Peter Igarashi
• 金额: $ 2.59万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-03 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8912182
• 关键词: Animal Model; Applications Grants; Area; Award; Basic Science; Biomedical Research; Cellular biology; Chronic Kidney Failure; Clinical; Clinical Research; Clinical Sciences; Collaborations; Diabetic Nephropathy; Diagnostic; Educational Grants; Electrolytes; Functional disorder; Genetic; Goals; Grant; Hypertension; Inherited; Institution; Internal Medicine; Kidney; Kidney Diseases; Laboratories; Lupus Nephritis; Medical center; Molecular; Nephrology; Pathogenesis; Pediatrics; Physiology; Polycystic Kidney Diseases; Process; Publishing; Reagent; Regulation; Research; Research Personnel; Scientist; Services; Texas; Therapeutic; Training; Translational Research; Universities; cellular imaging; clinical application; effective therapy; improved; insight; nephrogenesis; professor; programs; renal tubular transport; symposium; tool

This is an application for renewal of a George M. O'Brien Kidney Research Core Center at the University of Texas Southwestern Medical Center at Dallas. The Director is Dr. Peter Igarashi, Professor of Internal Medicine and Pediatrics, and Chief of the Division of Nephrology at UT Southwestern. The overall goal of the Center is to promote bidirectional interactions between basic scientists and clinical researchers that will fundamentally advance our understanding of kidney development and pathophysiology and result in more effective treatments of chronic kidney disease and it complications. To achieve this goal, the Center supports Biomedical Research Cores, Pilot & Feasibility Grants, and an Educational Enrichment Program. The four Biomedical Research Cores are: 1) Animal Models, 2) Physiology, 3) Cell Biology & Imaging, and 4) Clinical & Translational Research. The Cores support kidney research that is conducted by 49 investigators at UT Southwestern, three other academic institutions in North and Central Texas, and a foreign institution that is formally affiliated with UT Southwestern. Research is conducted in the areas of kidney development & genetics, renal physiology & pathophysiology, and chronic kidney disease. In addition, three of the Cores provide services or reagents that are widely utilized by off-campus kidney researchers located at numerous institutions throughout the U.S. and worldwide. Since its establishment in 2007, the Center has supported 111 published articles as well as new scientific collaborations and grant applications. Studies that are supported by the Center have provided new insights into the pathogenesis and treatment of congenital kidney abnormalities, polycystic kidney disease, lupus nephritis, diabetic nephropathy, electrolyte disturbances, and complications of chronic kidney disease. To expand the pool of kidney researchers, the Center awards two Pilot & Feasibility Grants per year to new investigators or established investigators from other fields. The Educational Enrichment Program includes a monthly research seminar, annual symposium, training grants, and courses offered through the Dept. of Clinical Sciences as well as practical hands-on training in each of the Cores.

这是续约乔治·M·奥布莱恩肾脏研究核心中心的申请 达拉斯的德克萨斯州西南医疗中心。董事是内部教授彼得·伊加拉西博士 医学和儿科，以及UT西南部肾脏科学系负责人。总体目标 中心是促进基础科学家和临床研究人员之间的双向相互作用 从根本上促进我们对肾脏发育和病理生理学的理解，并导致更多 有效治疗慢性肾脏疾病及其并发症。为了实现这一目标，中心支持 生物医学研究核心，飞行员和可行性赠款以及教育丰富计划。四个 生物医学研究核心是：1）动物模型，2）生理学，3）细胞生物学和成像，4）临床 ＆转化研究。核心支持UT的49位调查人员进行的肾脏研究 西南部，北部和德克萨斯州中部的其他三个学术机构，以及一个外国机构 正式隶属于UT西南部。研究是在肾脏发展和 遗传学，肾脏生理和病理生理学和慢性肾脏疾病。此外，三个核心 提供由众多校园外肾脏研究人员广泛使用的服务或试剂 美国和全球的机构。自2007年成立以来，该中心支持 111发表文章以及新的科学合作和赠款应用程序。研究 该中心的支持为先天性的发病机理和治疗提供了新的见解 肾脏异常，多囊性肾脏疾病，狼疮肾炎，糖尿病性肾病，电解质 慢性肾脏疾病的障碍和并发症。为了扩大肾脏研究人员的库 中心每年向新调查人员或已成熟的调查人员授予两项飞行员和可行性赠款 其他字段。教育丰富计划包括每月的研究研讨会，年度研讨会， 培训补助金以及通过临床科学系提供的课程以及实践的动手 在每个内核中进行训练。