2013 Matrix Metalloproteinase Gordon Research Conference and Gordon Research Semi

2013年基质金属蛋白酶戈登研究会议及戈登研究半会

基本信息

批准号：
8511050
负责人：
SUNEEL S APTE
金额：
$ 0.6万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-04-01 至 2014-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8511050
关键词：
Academia Area Arthritis Cardiovascular system Collaborations Communities Connective Tissue Diseases Data Disease Disease Pathway Disintegrins Disseminated Malignant Neoplasm Drug Industry Ensure Enzymes Equilibrium Extracellular Matrix Family Fostering Future Gender Goals Government Health Human Immersion Investigative Technique Industry Inflammatory International Italy Knowledge Lung Malignant Neoplasms Matrix Metalloproteinases Medical Mentors Metalloproteases Mission Molecular Neurologic Participant Pathway interactions Peptide Hydrolases Research Research Personnel Research Project Grants Resort Resource Sharing Scientific Advances and Accomplishments Scientist Time Translational Research Work abstracting astacin base career design experience fundamental research improved inhibitor/antagonist innovation interest meetings multidisciplinary next generation novel peer posters programs public health relevance racial and ethnic success symposium

项目摘要

DESCRIPTION (provided by applicant): The Gordon Research Conference (GRC) on Matrix Metalloproteinases (MMPs) (the MMP-GRC) is the premier meeting in a scientific field of exceptional importance for cancer, metastatic disease, connective tissue disorders such as arthritis, and numerous inflammatory, lung, cardiovascular and neurological conditions. The conference spans the full spectrum of fundamental and translational research on disease-relevant metalloproteinases that share catalytic and regulatory mechanisms, i.e., MMP, ADAM (a disintegrin and metalloproteinase), ADAMTS (ADAM with thrombospondin motifs) and astacin-like proteases, and their inhibitors. The 2013 MMP-GRC will be held at the Il Ciocco Tuscany Resort, Barga, Tuscany, Italy, from May 19-24, 2013 and is conjoined with a Gordon-Kenan Research Seminar (MMP-GRS) (May 18-19, 2013). The 2013 MMP-GRC and MMP-GRS are residential conferences, a tradition that has consistently led to the success of previous MMP-GRCs. The MMP-GRC and MMP-GRS provide an unparalleled forum for intermingling of trainees with established investigators. The residential format of the conference promotes close interactions, collaborations, and a sense of community in the participating scientists, who are drawn from academia, pharmaceutical industry and government sectors from around the world. The mission of the MMP- GRC and MMP-GRS is to advance scientific innovation with free exchange of ideas, to facilitate collaborations, and to nurture the next generation of scientists i the field, all with the ultimate goal of promoting human health. The 2013 MMP-GRC and MMP-GRS have a major disease focus on cancer, and an innovative thematic emphasis on metalloproteinases as integral components of molecular networks and disease pathways. The conference comprises 9 sessions that emphasize presentation of unpublished data and offer abundant time for discussion, with additional free time available for informal interactions. Sessions are chaired by experienced scientists, who are drawn from within the metalloproteinase community for their expertise, diversity and stature in the field. The international slate of speakers achieves a gender balance and representative cross-section of ethnic/racial diversity and includes numerous early-career investigators. Community renewal is emphasized by ensuring that the majority of invited speakers have not spoken before at a MMP-GRC. The conference program gives equal emphasis to fundamental and translational science. Each fundamental session is highly relevant to understanding cancer pathways, and there is an additional strong emphasis on extracellular matrix, which is relevant not only to cancer stroma, but also to connective tissue disease. Participants are selected based on their interest in and current activities relevant to the field, and on submitted abstracts of their ongoing work. A third of the conference platform presentations will be selected from the abstracts with two poster sessions allowing abundant time for discussion. We expect the conference to stimulate and inspire, and to set new goals and directions for cutting-edge research for the near future.

描述（由申请人提供）：关于基质金属蛋白酶（MMP）的戈登研究会议（GRC）（MMP-GRC）是科学领域的首次会议，对于癌症、转移性疾病、结缔组织疾病（例如关节炎、以及许多炎症、肺部、心血管和神经系统疾病。会议涵盖了与疾病相关的金属蛋白酶的全部基础和转化研究，这些金属蛋白酶具有催化和调节机制，即 MMP、ADAM（解整合素和金属蛋白酶）、ADAMTS（具有血小板反应蛋白基序的 ADAM）和虾红素样蛋白酶及其抑制剂。 2013年MMP-GRC将于2013年5月19日至24日在意大利托斯卡纳巴尔加的Il Ciocco托斯卡纳度假村举行，并与戈登-凯南研究研讨会（MMP-GRS）（2013年5月18日至19日）同时举行）。 2013 年 MMP-GRC 和 MMP-GRS 都是驻地会议，这一传统一直导致历届 MMP-GRC 的成功。 MMP-GRC 和 MMP-GRS 提供了一个无与伦比的论坛，使受训者与成熟的研究人员相互交流。会议的驻地形式促进了与会科学家的密切互动、合作和社区意识，这些科学家来自世界各地的学术界、制药行业和政府部门。 MMP-GRC 和 MMP-GRS 的使命是通过自由交流思想推进科学创新、促进合作并培养该领域的下一代科学家，最终目标是促进人类健康。 2013 MMP-GRC 和 MMP-GRS 的主要疾病重点是癌症，创新主题强调金属蛋白酶作为分子网络和疾病途径的组成部分。会议由 9 个会议组成，强调未发表数据的展示并提供充足的讨论时间，并有额外的空闲时间进行非正式互动。会议由经验丰富的科学家主持，他们来自金属蛋白酶界，具有该领域的专业知识、多样性和地位。国际演讲者名单实现了性别平衡和具有代表性的民族/种族多样性，其中包括许多早期职业调查员。通过确保大多数受邀演讲者之前没有在 MMP-GRC 上发言来强调社区更新。会议议程对基础科学和转化科学并重。每个基础课程都与了解癌症途径高度相关，并且特别强调细胞外基质，这不仅与癌症基质相关，而且与结缔组织疾病相关。参与者是根据他们对该领域的兴趣和当前与该领域相关的活动以及提交的正在进行的工作摘要来选择的。第三个会议平台的演讲将从摘要中选出，并举行两次海报会议，以便有充足的时间进行讨论。我们期望这次会议能够激发和启发，并为不久的将来的前沿研究设定新的目标和方向。