Center for Colon Cancer Research

结肠癌研究中心

• 批准号: 8913998
• 负责人: FRANKLIN G. BERGER
• 金额: $ 108.22万
• 依托单位: UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-10 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8913998
• 关键词: Advocacy; American; Area; Biometry; Biotechnology; Cancer Advocacy; Cancer Etiology; Centers of Research Excellence; Cessation of life; Collaborations; Colon Carcinoma; Colorectal Cancer; Development; Diagnosis; Disease; Economics; Exhibits; Extramural Activities; Faculty; Financial Support; Funding; Goals; Grant; Incidence; Journals; Knowledge; Laboratories; Mediating; Morbidity - disease rate; Mus; Outreach Research; Peer Review; Phase; Pilot Projects; Postdoctoral Fellow; Program Research Project Grants; Publications; Publishing; Research; Research Personnel; Research Project Grants; Scholarship; Scientist; Seeds; Services; South Carolina; Students; Technology; Tissues; Training; Underrepresented Minority; Universities; anticancer research; base; biobank; design; experience; improved; member; novel; operation; outreach program; prevent; programs; public health relevance; screening; symposium

DESCRIPTION (provided by applicant): This Phase III COBRE application seeks to support and sustain the momentum achieved during developmental Phases I and II of the Center for Colon Cancer Research (CCCR) at the University of South Carolina. In the US and South Carolina, colorectal cancer remains the 2nd leading cause of cancer death and the 4th highest in incidence. In the 91/2 years since COBRE funding was initiated, the CCCR has made significant strides in enhancing the critical mass of independent scientists studying this disease, as judged by establishment of fully functional laboratories, receipt of extramural research grants, and publication in highly regarded, peer-reviewed journals. In addition, a vibrant outreach program has been designed and implemented to educate citizens from diverse economic backgrounds about colorectal cancer and the value of screening, making South Carolina a national leader in advocacy for this disease. The CCCR is now a fully established, self-standing center that contributes to the nation's goal of reducing the morbidity of colorectal cancer. To carry on with this effort, the CCCR will implement the following aims during Phase III: Provision of administrative services and support through the Administrative Core. Support of financial, programmatic, and training aspects of the CCCR research and outreach effort will be provided. Operation of a group of interactive Research Cores. CCCR investigators will have state-of-the-art expertise and technology available through four Cores, each of which is led by an experienced and knowledgeable member of the CCCR faculty. Oversight of a Research Pilot Project Program. Through fiscal support for development of investigator initiated seed projects, as well as development of multi-disciplinary programs, the Pilot Project effort will enable entry into challenging new research areas, and will mediate unique collaborations. In addition, the project will manage a graduate scholarship program for underserved minorities. In all, the wide range of knowledge and proficiency exhibited by the interdisciplinary faculty comprising the CCCR provides the basis for sustaining, during Phase III period, that which was built during Phases I and II.

描述（由申请人提供）：本III阶段的申请旨在支持和维持南卡罗来纳大学结肠癌研究中心（CCCR）的发育阶段I和II期间所取得的势头。在美国和南卡罗来纳州，大肠癌仍然是癌症死亡的第二大原因，发病率是第四高。自从圆锥筹资金开始以来的91/2年中，CCCR在增强研究这种疾病的独立科学家的关键质量方面取得了长足的进步，这是根据建立功能齐全的实验室，收到壁外研究补助的判断，并在受到高度关注的，同行评审的期刊上发表。此外，已经设计和实施了一项充满活力的外展计划，以教育来自多种经济背景的公民有关结直肠癌和筛查的价值，使南卡罗来纳州成为这种疾病倡导的国家领导者。 CCCR现在是一个完全建立的，独立的中心，有助于该国降低结直肠癌的发病率的目标。为了继续这项工作，CCCR将在第三阶段实施以下目标： 通过行政核心提供行政服务和支持。将提供CCCR研究和外展工作的财务，程序化和培训方面的支持。 一组互动研究核心的操作。 CCCR调查人员将拥有通过四个核心提供的最先进的专业知识和技术，每个核心都由CCCR教师的经验丰富且知识渊博的成员领导。 监督研究试点项目计划。通过对研究人员开发的启动种子项目的支持以及多学科计划的开发，试点项目工作将使进入挑战的新研究领域，并将调解独特的合作。此外，该项目将管理服务不足少数民族的研究生奖学金计划。 总的来说，包括CCCR的跨学科教师所表现出的广泛的知识和水平为维持III期时期内建立的知识和水平提供了基础。