Training in Host-pathogens interactions

宿主与病原体相互作用的培训

• 批准号: 8662688
• 负责人: DAVID M MOSSER
• 金额: $ 6.47万
• 依托单位: UNIV OF MARYLAND, COLLEGE PARK
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2016-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8662688
• 关键词: Training; pathogen

DESCRIPTION (provided by applicant): We are seeking support to train graduate students over a five year period in the area of host-pathogen interactions. Seventeen investigators in 5 colleges at the University of Maryland whose primary research interest pertains to host-pathogen interactions have come together to form a research cluster in the newly- formed BISI graduate program in the College of Chemical and Life Sciences. The devastating effects of infectious diseases caused by pathogens such as tuberculosis, meningitis, leishmaniasis, influenza and other parasitic infections, etc. are well known, and efforts to understand the mechanisms of microbial pathogenesis are easily justified from a world health perspective. The importance of microbial pathogens extends well beyond the diseases they cause, because studying their pathogenesis will lead to new insights in immunology and cellular biology. Thus, this is an excellent area for graduate student training. This training proposal seeks support for a unique training program that will immerse students in interdisciplinary research, striving to integrate advances in genomics, immunology, and microbial pathogenesis with our rapidly expanding understanding of host-pathogen interactions. The goal of this program is to train graduate students in basic cell and molecular biology of host-pathogen interactions, with an eye to developing translational approaches to improve health. RELEVANCE (See instructions): Pathogens infect nearly all life forms and many have the potential to cause world-wide pandemics. This training proposal seeks support to train predoctoral students to meet the research challenges that these diseases are likely to create. The diverse faculty will bring a variety of expertise to bear on problems that are common to studying host-pathogen interactions. This program includes developing strategies to protect humans and animals to improve the quality of people's lives.

描述（由申请人提供）：我们正在寻求支持，以在五年内培训宿主-病原体相互作用领域的研究生。马里兰大学 5 个学院的 17 名主要研究兴趣涉及宿主与病原体相互作用的研究人员聚集在一起，在化学与生命科学学院新成立的 BISI 研究生项目中形成了一个研究集群。结核病、脑膜炎、利什曼病、流感和其他寄生虫感染等病原体引起的传染病的破坏性影响是众所周知的，从世界健康的角度来看，了解微生物发病机制的努力很容易证明是合理的。微生物病原体的重要性远远超出了它们引起的疾病，因为研究它们的发病机制将为免疫学和细胞生物学带来新的见解。因此，这是研究生培养的绝佳领域。该培训提案寻求对独特培训计划的支持，该培训计划将使学生沉浸在跨学科研究中，努力将基因组学、免疫学和微生物发病机制的进步与我们对宿主-病原体相互作用的快速扩展的理解相结合。该项目的目标是培养研究生宿主与病原体相互作用的基础细胞和分子生物学知识，着眼于开发改善健康的转化方法。 相关性（参见说明）：病原体几乎感染所有生命形式，其中许多有可能引起世界范围内的流行病。该培训提案寻求支持培训博士前学生，以应对这些疾病可能带来的研究挑战。多元化的教师将带来各种专业知识来解决研究宿主与病原体相互作用的常见问题。该计划包括制定保护人类和动物的战略，以提高人们的生活质量。