PRIDE-Functional and Applied Genomics of Blood Disorders

PRIDE-血液疾病的功能和应用基因组学

基本信息

批准号：
8521359
负责人：
Betty Sue Pace
金额：
$ 30.88万
依托单位：
AUGUSTA UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-09-20 至 2014-09-12
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8521359
关键词：
Address Applications Grants Area Behavioral Sciences Biomedical Research Blood Clinical Research Protocols Collaborations Complement Country Development Disabled Persons Educational process of instructing Educational workshop Ensure Environment Equilibrium Faculty Fostering Funding Genomics Goals Grant Health Heart Heart Diseases Hematological Disease Individual Institutes Institution Knowledge Learning Lung Lung diseases Mentors Mentorship Minority Morbidity - disease rate National Heart, Lung, and Blood Institute Outcome Population Private Sector Program Evaluation Public Health Public Sector Recruitment Activity Reporting Research Research Personnel Research Priority Research Project Grants Research Technics Research Training Scientist Sleep Disorders Testing Texas Training Training Programs Training Technics Universities Visit Writing abstracting base career design didactic education experience functional genomics health disparity improved interest mortality multidisciplinary programs public health relevance skills skills training

项目摘要

DESCRIPTION (provided by applicant): Project Summary/Abstract: Reports from the private and public sectors provide strong evidence that diversity remains an important challenge in biomedical and behavioral science research programs. To address these issues a Summer Institute Program to Increase Diversity (SIPID)-Functional Genomics of Blood Disorders was funded in 2006 by the National Heart Lung Blood Institute (NHLBI) at the University of Texas at Dallas. We recruited 25 junior faculty mentees who were assigned mentors from a pool of leading investigators in their area of research focus. We taught mentees diverse topics and hands-on bench research and grantsmanship skills. Program evaluations suggest the SIPID program will achieve its primary goal of aiding mentees in obtaining independent grant funding within two years of program completion. We propose to continue this mentored training program to improve the recruitment and retention of underrepresented and disabled faculty in health-related careers. We will establish a Program to Increase Diversity Among Individuals Engaged in Health-Related Research (PRIDE)-Functional and Applied Genomics of Blood Disorders to complete the following aims. Aim 1 (PRIDE 1): In collaboration with the Coordination Core, Mentorship Committees will be established and long-term partnerships developed based on the research interests of mentees and expertise of mentors. A multidisciplinary didactic curriculum related to functional and applied genomics research, grant writing skills and hands-on-bench research techniques will be designed to increase the knowledge and skills of mentees. Aim 2 (Mentoring and Networking Activity): The continued development of the mentor- mentee relationship will be fostered by regular contact with the Mentoring Committee throughout the year. A mid-year visit to the mentor's institution will be sponsored to refine the mentee's research project, grant writing skills, career planning, and additional bench training techniques. Aim 3 (PRIDE 2): PRIDE mentees will continue to develop grantsmanship skills and refine their research projects in order to submit a grant application to acquire NHLBI-sponsored funding. The need for a diverse workforce permeates all aspects of the nation's public health-related research efforts. The PRIDE initiative will fund summer institutes to enable junior faculty to further develop their research skills and knowledge in order to increase the number of underrepresented and disabled scientists in biomedical research careers. Because underrepresented individuals suffer a disproportionate burden of morbidity and mortality associated with heart, lung, blood, and sleep disorders, there is a critical need to increase the number of investigators conducting research on health disparities in this area. PUBLIC HEALTH RELEVANCE: Project Narrative: Currently there exists a growing disparity in the number of minority scientists engaged in biomedical research. Mentoring and training are essential to the retention and recruitment of underrepresented and disabled faculty. The PRIDE-Functional and Applied Genomics of Blood Disorders Summer Institute at the University of Texas at Dallas (UTD) will address these challenges by establishing mentor-mentee partnerships based on common research interests. In addition, the program will provide the mentees with research experiences in functional and applied genomics, develop grantsmanship skills, develop specific research projects, and improve their long-term fundability. The UTD-PRIDE program will strategically complement the efforts of the National Heart Lung and Blood Institute to promote and diversify the country's biomedical workforce.

描述（由申请人提供）：项目摘要/摘要：来自私营和公共部门的报告提供了强有力的证据，表明多样性仍然是生物医学和行为科学研究项目中的一个重要挑战。为了解决这些问题，达拉斯德克萨斯大学国家心肺血液研究所 (NHLBI) 于 2006 年资助了一项增加多样性夏季研究所计划 (SIPID)——血液疾病功能基因组学。我们招募了 25 名初级教员，他们从各自研究领域的顶尖研究人员中担任导师。我们向学员传授各种主题以及实践基础研究和资助技能。项目评估表明，SIPID 项目将实现其主要目标，即帮助学员在项目完成后两年内获得独立赠款资金。我们建议继续开展这一指导培训计划，以改善健康相关职业中代表性不足和残疾教师的招聘和保留。我们将制定一项增加多样性的计划从事健康相关研究 (PRIDE) 的个人 - 血液疾病的功能和应用基因组学以完成以下目标。目标 1（PRIDE 1）：与协调核心合作，将建立导师委员会，并根据受训者的研究兴趣和导师的专业知识发展长期合作伙伴关系。将设计与功能和应用基因组学研究、资助写作技巧和实践研究技术相关的多学科教学课程，以提高学员的知识和技能。目标 2（指导和交流活动）：全年定期与指导委员会联系，以促进指导者与受训者关系的持续发展。将赞助对导师所在机构的年中访问，以完善受训者的研究项目、资助写作技巧、职业规划和其他基础培训技巧。目标 3 (PRIDE 2)：PRIDE 学员将继续发展资助技能并完善他们的研究项目，以便提交资助申请以获得 NHLBI 资助的资金。对多元化劳动力的需求渗透到国家公共卫生相关研究工作的各个方面。 PRIDE 计划将资助暑期学院，使初级教师能够进一步发展他们的研究技能和知识，从而增加生物医学研究职业中代表性不足和残疾科学家的数量。由于代表性不足的个人承受着与心脏、肺、血液和睡眠障碍相关的发病率和死亡率不成比例的负担，因此迫切需要增加对该领域的健康差异进行研究的研究人员数量。公共卫生相关性：项目叙述：目前，从事生物医学研究的少数族裔科学家的数量差距越来越大。指导和培训对于留住和招聘代表性不足和残疾教师至关重要。德克萨斯大学达拉斯分校 (UTD) 的 PRIDE-血液疾病功能和应用基因组学夏季研究所将通过建立基于共同研究兴趣的导师与学员伙伴关系来应对这些挑战。此外，该计划将为学员提供功能和应用基因组学的研究经验，培养资助技能，开发具体的研究项目，并提高他们的长期资助能力。 UTD-PRIDE 计划将从战略上补充国家心肺和血液研究所的努力，以促进国家生物医学劳动力并使之多样化。