USC Cardiothoracic Surgical Trials Network Core Clinical Center

南加州大学心胸外科试验网络核心临床中心

基本信息

批准号：
8802893
负责人：
Michael Eugene Bowdish
金额：
$ 38.89万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-07-15 至 2016-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8802893
关键词：
Address Adult Ally Anesthesiology Aortic Aneurysm Bioinformatics Biometry California Cardiac Surgery procedures Cardiology Cardiovascular Diseases Cardiovascular system Caring Cessation of life Chest Clinical Clinical Research Clinical Sciences Clinical Trials Design Coronary Artery Bypass Critical Care Death Rate Disease Dissection Economics Education Enrollment Ethnic Origin Expenditure Goals Health Policy Healthcare Hispanics Institutes Intervention Location Los Angeles Medical Morbidity - disease rate Nafion Nature Neurology Operative Surgical Procedures Outcome Patient Care Patients Pharmacy Schools Population Heterogeneity Positioning Attribute Price Principal Investigator Public Policy Race Randomized Randomized Clinical Trials Recording of previous events Recruitment Activity Registries Research Research Personnel Research Proposals Resources Schools Site Socioeconomic Status Surgeon Surgical Management Therapeutic Translational Research United States Universities collaborative trial cost data management evidence base experience improved innovation medical schools medical specialties mortality patient population programs protocol development quality assurance repaired socioeconomics success tool ventricular assist device

项目摘要

DESCRIPTION (provided by applicant): The Division of Cardiothoracic Surgery at the Keck School of Medicine of USC and the University of Southern California, with its collaborators throughout the University, is committed to becoming a Core Clinical Center (CCC) for the Cardiothoracic Surgical Trials Network (CTSN). The specific aim of this research proposal is to describe the experience, expertise, collaborative nature, and resources available at the Keck School of Medicine of USC and the University of Southern California that will substantially contribute to the success of the CTSN. We believe that our program is ideally suited to participate in the CTSN as a CCC for the following reasons: (1) the University and Division's commitment to excellence in patient care, research, education, and innovation; (2) Demonstrated commitment to the CTSN by the Division, Principal Investigator and Co-lnvestigator as a CTSN Satellite Site since 2010; (3) our robust cardiothoracic surgical practice which performs nearly 1000 major cardiac surgical procedures each year; (4) our unique location in Los Angeles and access to the LAC+USC HealthCare Network, which provides access to a racially, ethnically, and socioeconomically diverse population, with an especially large Hispanic population; (4) our demonstrated ability to identify, recruit, randomize, and retain patients from our large patient population; (5) our extensive history of clinical and surgical excellence and innovation and prominent position in cardiovascular care; (6) the demonstrated excellence of our clinical research unit which over the last five years has enrolled over 500 patients in clinical cardiothoracic surgery trials and maintains an active observational registry o over 2600 patients; (7) and our ability to coalesce a multi-disciplinary Core Clinical Center with experts from multiple clinical specialties, in addition to experts from the Southern California Clinical and Translational Science Institute (CTSI), the Leonard D. Schaeffer Center for Health Policy Economics, the USC CTSI Biostatistics and Bioinformatics Resource Group, and the USC Center for Body Computing.

描述（由申请人提供）：南加州大学凯克医学院和南加州大学的心胸外科手术部，其整个大学的合作者致力于成为心胸外科手术外科手术试验的核心临床中心（CCC）网络（CTSN）。这项研究建议的具体目的是描述USC凯克医学院和南加州大学提供的经验，专业知识，协作性质和资源，这将有助于CTSN的成功。我们认为，由于以下原因，我们的计划非常适合作为CCC参加CCC：（1）大学和部门对卓越患者护理，研究，教育和创新的承诺；（2）自2010年以来，该部门，首席研究员和共同vestigator对CTSN表示承诺；（3）我们强大的心胸外科手术实践，每年进行近1000个主要的心脏手术程序；（4）我们在洛杉矶的独特地点，并访问LAC+USC Healthcare网络，该网络可访问种族，种族和社会经济多样性的人口，具有特别大的西班牙裔人口；（4）我们证明的识别，招募，随机和保留的能力来自我们庞大的患者人群的患者；（5）我们在临床和外科手术卓越和创新方面的广泛历史以及心血管护理中的重要地位；（6）在过去的五年中，我们的临床研究部门表现出了卓越的表现，该单位已招募了500多名患者参加临床心胸外科手术试验，并维持了2600名患者的活跃观察注册中心；（7）以及我们与来自多个临床专业专家的多学科核心临床中心合并的能力，除了南加州临床和转化科学研究所（CTSI）的专家外，伦纳德·D·舍弗（Leonard D. USC CTSI生物统计学和生物信息学资源组以及USC人体计算中心。