2015 Aging, Biology of Gordon Research Conference and Gordon Research Seminar

2015年衰老、生物学戈登研究会议暨戈登研究研讨会

• 批准号: 8975254
• 负责人: John M Sedivy
• 金额: $ 5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-06-15 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8975254
• 关键词: Academia; Age; Aging; Aging-Related Process; Animal Model; Area; Autophagocytosis; Basic Science; Biological; Biological Models; Biology; Biology of Aging; Cell Aging; Cells; Chronic Disease; Communication; Complex; Data; Disease; Educational workshop; Elderly; Enrollment; Ensure; Epigenetic Process; Experimental Models; Explosion; Faculty; Feedback; Fostering; Funding; Funding Agency; Future; Genetic; Genome Stability; Geriatrics; Gerontology; Glean; Goals; Government; Health; Homeostasis; Human; Human Biology; Individual; Industry; International; Intervention; Invertebrates; Investigation; Knowledge; Lead; Link; Location; Longevity; Maine; Medical; Metabolic; Mitochondria; Molecular; Neurosecretory Systems; Pathway interactions; Physiological; Postdoctoral Fellow; Prevention strategy; Process; Proteins; Quality of life; Recording of previous events; Regulation; Rejuvenation; Request for Applications; Research; Research Personnel; Resort; Rivers; Scientist; Series; Shapes; Societies; Stem cells; Structure; Students; Therapeutic; Therapeutic Intervention; Time; Tissues; Training; Translating; Translational Research; Travel; Work; abstracting; age related; base; career; career development; design; drug discovery; experience; functional decline; graduate student; insight; meetings; next generation; novel; peer; planetary Atmosphere; posters; programs; psychologic; public health relevance; role model; social; successful intervention; symposium; telomere; treatment strategy

 DESCRIPTION (provided by applicant): This application requests funds to support the 2015 Gordon Research Conference (GRC) on the Biology of Aging, to be held at the Sunday River Resort (Newry, Maine, USA) on July 19-24, 2015, and the Gordon- Kenan Research Seminar (GRS), which will be held at the same location on July 18-19, immediately prior to the GRC. This will be the thirtieth meeting since the inception of this series in 1962. While geriatrics and gerontology societies and their meetings have maintained an emphasis on the medical, social and psychological ramifications of aging, the last two decades have seen an explosion of knowledge on the most fundamental molecular aspects of the aging process. Investigators performing basic research in this area, many using invertebrate model systems, increasingly sought the Biology of Aging GRC as an excellent forum for the presentation of recent data and networking. Emerging from this watershed period, the modern concept of the biology of aging is still a relatively new field, and this GRC has become the premier forum for discussions at the forefront of current inquiry. As a result, the historically separate areas of the basic biology of aging and the investigation and treatment of chronic diseases have begun to merge around common molecular principles. In part due to the influence of the Biology of Aging GRC, the field has embraced the concept that elucidating the basic mechanisms of longevity will advance our fundamental understanding of the molecular basis of important diseases and vice versa. These insights are expected to lead to novel preventive and treatment strategies, which will have a profound impact on enhancing the quality of life for the elderly. To continue, and in fact put this journey in fast forward, the theme of the 2015 conference will be The Translational Science of Aging: From Functional Pathways to Interventions. To catalyze reciprocal feedback between investigators in diverse areas sessions were organized around the following themes: Epigenetics and Genome Stability, Genetics of Aging, Telomeres and Cellular senescence, Stem Cells and Rejuvenation, Protein Homeostasis and Autophagy, Neuroendocrine Regulation, and Metabolic Regulation and Mitochondria. The meeting will conclude with a round-table discussion on developing therapeutic strategies for aging and age-associated diseases. Our organizational principles are to develop: 1) A program that focuses on mechanistic advances that inform human aging and have significant therapeutic implications; 2) An atmosphere that facilitates reciprocal exchange between scientists working in experimental models and those involved in studies of human biology; 3) A venue that promotes interactions among established investigators and newcomers to the field; and 4) A strategy to foster recruitment, retention and career advancement of junior investigators.

 描述（由申请人提供）：本申请请求资金支持 2015 年衰老生物学戈登研究会议 (GRC)，该会议将于 2015 年 7 月 19 日至 24 日在星期日河度假村（美国缅因州纽里）举行，戈登-凯南研究研讨会 (GRS) 将于 7 月 18 日至 19 日在 GRC 之前的同一地点举行。自 1962 年本系列开始以来一直在召开会议。虽然老年病学和 老年学协会及其会议一直强调衰老的医学、社会和心理影响，在过去的二十年里，人们对衰老过程最基本的分子方面的知识有了爆炸性的增长，许多研究人员在这一领域进行基础研究。使用无脊椎动物模型系统，越来越多地寻求衰老生物学 GRC 作为展示最新数据和网络的绝佳论坛。从这个分水岭时期出现的衰老生物学的现代概念仍然是一个相对较新的领域，并且该 GRC 已经成为当前研究前沿讨论的首要论坛。因此，历史上独立的衰老生物学和慢性病的研究和治疗领域开始围绕共同的分子原理合并。在衰老生物学 GRC 的研究中，该领域接受了这样的概念：阐明长寿的基本机制将促进我们对重要疾病的分子基础的基本理解，反之亦然。这些见解预计将带来新的预防和治疗策略。将对提高人们的生活质量产生深远的影响继续说下去，其实就这个了。 展望未来，2015 年会议的主题将是“衰老的转化科学：从功能途径到干预”，为了促进不同领域研究人员之间的相互反馈，会议围绕以下主题组织：表观遗传学和基因组稳定性、衰老遗传学。 、端粒和细胞衰老、干细胞和复兴、蛋白质稳态和自噬、神经内分泌调节和代谢调节和会议将以关于制定衰老和年龄相关疾病的治疗策略的圆桌讨论结束，我们的组织原则是制定：1）一项重点关注人类衰老机制进展并具有重大治疗意义的计划； 2) 促进从事实验模型工作的科学家和参与人类生物学研究的科学家之间相互交流的氛围； 3) 促进该领域现有研究人员和新人之间互动的场所；以及 4) 促进招募、保留和培养的策略；职业发展初级调查员。