Examining Innovative Obesity Treatment and Related Novel Constructs

检查创新的肥胖治疗方法和相关的新颖结构

基本信息

批准号：
8925856
负责人：
RACHEL D BARNES
金额：
$ 15.59万
依托单位：
YALE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-09-20 至 2018-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8925856
关键词：
Address Appointment Area Attention Behavior Behavioral Binge Eating Binge eating disorder Body Weight decreased Clinic Clinical Collaborations Communities Conduct Clinical Trials Counseling Data Development Diet Doctor of Philosophy Eating Epidemic Equipment and supply inventories Ethics Extramural Activities Faculty Food Funding Future Goals Health behavior Health education Individual Internet Intervention Joints Knowledge Learning Literature Measurement Measures Mentored Patient-Oriented Research Career Development Award Mentors Mentorship Metabolic syndrome Methodology Methods North Carolina Nutritional Obesity Online Systems Outcome Overweight Paper Patients Population Primary Health Care Property Provider Psychiatry Psychological Factors Psychology Psychometrics Public Health Public Health Schools Publications Publishing Randomized Clinical Trials Randomized Controlled Trials Research Research Activity Research Design Research Personnel Research Project Grants Research Training Route Sampling Symptoms System Thinking Time Training Universities Weight Work base career development compliance behavior design eating pathology experience improved innovation interest medical schools medical specialties member motivational enhancement therapy multidisciplinary novel nutrition obesity treatment post-doctoral training professor programs psychologic skills treatment as usual treatment response weight loss intervention

项目摘要

DESCRIPTION (provided by applicant): This application is for a Mentored Patient-Oriented Research Career Development Award (K23). The candidate, Rachel D. Barnes, Ph.D., has a programmatic interest in innovative treatments for overweight and obesity within multidisciplinary teams and furthering understanding of novel weight-related variables. Dr. Barnes plans, as a junior faculty member at Yale University School of Medicine (YSM), to acquire the necessary skills to successfully obtain extramural funding and become an independent clinical researcher in the area of obesity. The training and research plan comprises the expert mentorship and collaboration of Carlos M. Grilo, Ph.D., Professor of Psychiatry at YSM, Professor of Psychology at Yale University, and Director of the Program for Obesity, Weight, and Eating Research, and Deborah Tate, Ph.D., Associate Professor with joint appointments in the Gillings School of Public Health in the Departments of Health Behavior and Health Education, and the Department of Nutrition at the University of North Carolina School of Medicine, Chapel Hill. These mentors, along with internationally recognized contributors from YSM, will assist Dr. Barnes in achieving and maximizing the training and research plans. Dr. Barnes plans to devote a minimum of 75% of her time to obtaining further knowledge and expertise in behavioral and psychological factors associated with obesity and in intervening with overweight and obesity. Her specific training development goals proposed for the K23 are to: 1) Acquire greater expertise with assessing and intervening with obesity in different settings; 2) Design and conduct a randomized clinical trial; and 3) Obtain training and perform research in psychological approaches relevant to improving clinical methods for intervening for obesity. The research plan for this application is comprised of three interrelated studies designed to: 1) Validate the Food Thought Suppression Inventory (FTSI) within an overweight and obese treatment seeking sample; 2) Examine the FTSI within a randomized controlled trial (RCT) for binge eating disorder; and 3) Conduct an innovative RCT treating obesity within primary care using an easily accessible and financially feasible internet treatment enhanced with motivational interviewing. Collectively, these studies will increase Dr. Barnes's knowledge of ethics and complexities of conducting clinical trials, including statistical sophistication and methodologies, and will inform the development of R01 applications. The proposed research has the potential to improve our understanding of a systems based, broad approach to treating obesity and novel weight-related constructs. The K23 will support Dr. Barnes's transition to an independent clinical-researcher in the field of obesity.

描述（由申请人提供）：此申请是为受过指导的以患者为导向的研究职业发展奖（K23）的。候选人瑞秋·巴恩斯（Rachel D. Barnes博士计划是耶鲁大学医学院（YSM）的初级教职员工，以获取成功获得校外资金并成为肥胖领域的独立临床研究人员的必要技能。培训和研究计划包括Carlos M. Grilo博士的专家指导与合作，YSM精神病学教授，YALE大学心理学教授，肥胖，体重和饮食研究计划以及Deborah Tate，Deborah Tate，Ph.D。博士学位，与吉尔大学健康部门的联合教育，该部门健康部门的联合教育，该部门的健康部门，该部门的健康部门，该部门的健康部门，兄弟院士的健康部门。北卡罗来纳州医学院，教堂山。这些导师以及来自YSM的国际认可的贡献者将帮助Barnes博士实现和最大化培训和研究计划。 Barnes博士计划将至少75％的时间投入到与肥胖相关的行为和心理因素以及与超重和肥胖有关的行为和心理因素方面的进一步知识和专业知识。她针对K23提出的特定培训发展目标是：1）在评估和干预不同环境中的肥胖症方面获得更大的专业知识； 2）设计和进行随机临床试验； 3）获得与改善临床方法相关的心理方法的培训并进行研究。该应用的研究计划由三个相互关联的研究组成：1）在寻求样本的超重和肥胖治疗中验证食物思想抑制清单（FTSI）； 2）检查一次随机对照试验（RCT）中的FTSI，以实现暴饮暴食障碍； 3）使用易于获得且在经济上可行的互联网治疗中通过动机访谈来进行创新的RCT治疗初级保健中的肥胖症。总的来说，这些研究将增加Barnes博士对进行临床试验（包括统计复杂和方法）的伦理和复杂性的了解，并将为R01应用的发展提供信息。拟议的研究有可能提高我们对基于系统的广泛方法来治疗肥胖和新型与体重相关的构建体的理解。 K23将支持Barnes博士向肥胖领域的独立临床研究者的过渡。