University of Massachusetts Center for Clinical and Translational Science

马萨诸塞大学临床与转化科学中心

基本信息

批准号：
9086537
负责人：
Katherine F Luzuriaga
金额：
$ 321.91万
依托单位：
UNIV OF MASSACHUSETTS MED SCH WORCESTER
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-08-14 至 2019-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9086537
关键词：
Address Age Award Back Basic Science Behavioral Medicine Behavioral Sciences Biological Sciences Boston Businesses Cardiovascular system Categories Certification Childhood Clinical Clinical Medicine Clinical Research Clinical Sciences Clinical Trials Collaborations Communicable Diseases Communication Communities Community Health Data Analyses Development Device or Instrument Development Devices Diabetes Mellitus Disadvantaged Discipline Discipline of Nursing Disease Doctor of Philosophy Economics Ecosystem Education Educational Curriculum Elderly Engineering Ensure Environment Ethnic Origin Expenditure FarGo Fertilization Fostering Funding Future Gender Geographic Locations Geriatrics Goals Good Clinical Practice Grant Growth Guidelines Health Healthcare Human Individual Industry Institution International International Health Problems Knowledge Laws Leadership Legal patent Lesbian Gay Bisexual Transgender Licensing Link Location Longevity Malignant Neoplasms Massachusetts Maternal and Child Health Medical Device Medical Students Mentors Mentorship MicroRNAs Mission Molecular NCI Scholars Program Neurology Occupations Outcome Pathway interactions Phase Policies Population Positioning Attribute Preventive Medicine Process Public Health RNA Interference Race Recruitment Activity Reporting Research Research Infrastructure Research Personnel Resources Safety Science Services Sex Orientation Socioeconomic Status Solutions Strategic Planning Support System System Testing Training Training Programs Training Support Transcend Translational Research Translations Universities Vision Work abstracting base bench to bedside career career development cost effective design didactic education experience global health health disparity improved innovation multidisciplinary next generation novel novel strategies organizational structure population health post-doctoral training programs public-private partnership response skills success tool

项目摘要

Contact PD/PI: Luzuriaga, Katherine PROJECT SUMMARY/ABSTRACT The University of Massachusetts (UMass) Center for Clinical and Translational Science (UMCCTS) was organized with the vision of transforming clinical and translational research (CTR) and education across the five UMass campuses and our clinical partner, UMass Memorial Health Care (UMMHC). Specific goals were to leverage our scientific strengths and unique resources: 1) to accelerate the translation of discoveries into practical, cost effective solutions that improve human health; and 2) to train the next generation of leaders in CTR. Over the past five years, the UMCCTS has fostered a culture of trans-disciplinary collaboration; provided cores, services, and pilot programs; and developed innovative educational and training programs. We have capitalized on our outstanding basic science research to create an ecosystem that accelerates early phase translation and have facilitated the development of nationally recognized programs in community engagement, health disparities, outcomes, and Global Health. Public-private partnerships have positioned UMass campuses as hubs in the Massachusetts (MA) innovation economy. We will continue to build the UMCCTS for statewide, national, and international collaboration and impact by: 1. Building and supporting an innovative and collaborative translational workforce with the knowledge and expertise to advance high impact CTR. Using an active approach to solving real-world problems that combines didactic education, experiential training, and integrated mentorship to facilitate team science, we will expand CTR educational and training opportunities through revamped curricula, a new PhD and postdoctoral training program (linked TL1 award), an enhanced KL2 Scholars program, increased training opportunities and career support for our entire CTR workforce; 2. Engaging stakeholders to build enabling systems and trans- disciplinary teams that provide the scientific expertise, funding, processes, and tools conducive to effective CTR. We will continue to expand public-private partnerships that build out the UMCCTS as a contributing partner in the national CTSA network; we will particularly work to build capacity to identify and advance products for clinical development. We will also collaborate with the CTSA network on testing new approaches to improving the design, completion, and reporting of clinical trials that result in improved population, community, and global health; 3. Integrating translational science across its multiple phases, diverse disciplines, within disadvantaged populations, and across the lifespan. We will capitalize on specific expertise in disparities, LGBT, pediatric, and geriatric research along with successes in community engagement to maximize the impact of our work on health improvement at the local, national, and global levels. 4. Testing new approaches to develop and evaluate the impact of policies, processes, and platforms that support innovation, quality, safety, and efficiency in CTR. Project Summary/Abstract Page 158 Contact PD/PI: Luzuriaga, Katherine

联系人 PD/PI：Luzuriaga、Katherine 项目概要/摘要马萨诸塞大学 (UMass) 临床与转化科学中心 (UMCCTS) 组织的愿景是改变整个临床和转化研究（CTR）和教育五个麻省大学校园和我们的临床合作伙伴麻省大学纪念医疗保健中心 (UMMHC)。具体目标是利用我们的科学优势和独特资源：1）加速发现的转化转化为改善人类健康的实用且具有成本效益的解决方案； 2）训练下一代点击率的领导者。在过去的五年里，UMCCTS 培育了一种跨学科的文化合作;提供核心、服务和试点计划；并开发创新的教育和培训程序。我们利用出色的基础科学研究来创建一个生态系统加速了早期阶段的翻译并促进了国家认可的项目的开发社区参与、健康差异、结果和全球健康。公私伙伴关系已将麻省大学校园定位为马萨诸塞州 (MA) 创新经济的中心。我们将继续通过以下方式建立 UMCCTS，以促进全州、国家和国际合作并产生影响： 1. 建立和通过知识和专业知识支持创新和协作的翻译团队提高高影响力的点击率。使用积极的方法来解决结合教学的现实问题教育、体验式培训和综合指导以促进团队科学，我们将扩大点击率通过修改课程、新的博士和博士后培训提供教育和培训机会计划（链接 TL1 奖项）、增强的 KL2 学者计划、增加的培训机会和职业生涯对我们整个 CTR 员工队伍的支持； 2. 让利益相关者参与构建支持系统和跨部门合作提供科学专业知识、资金、流程和工具的学科团队，有利于有效的点击率。我们将继续扩大公私伙伴关系，将 UMCCTS 打造为一个国家 CTSA 网络的贡献合作伙伴；我们将特别努力建设能力，以识别和用于临床开发的先进产品。我们还将与 CTSA 网络合作测试新的改进临床试验的设计、完成和报告的方法，从而改进人口、社区和全球健康； 3. 整合转化科学的多个阶段，不同学科、弱势群体和整个生命周期。我们将利用在差异、LGBT、儿科和老年研究方面的具体专业知识以及社区的成功参与以最大限度地提高我们的工作对地方、国家和全球健康改善的影响水平。 4. 测试新方法来制定和评估政策、流程和政策的影响支持 CTR 创新、质量、安全和效率的平台。项目总结/摘要第 158 页联系人 PD/PI：Luzuriaga、Katherine