University of Massachusetts Center for Clinical and Translational Science

马萨诸塞大学临床与转化科学中心

基本信息

批准号：
8490525
负责人：
Katherine F Luzuriaga
金额：
$ 57.83万
依托单位：
UNIV OF MASSACHUSETTS MED SCH WORCESTER
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-07-01 至 2015-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8490525
关键词：
Address Admission activity Award Basic Science Biological Sciences Clinical Clinical Investigator Clinical Research Clinical Sciences Clinical effectiveness Commit Communities Community Outreach Community Participation Core Facility Data Analyses Devices Distance Learning Education Educational Curriculum Educational workshop Enrollment Environment Evaluation Faculty Foundations Funding Generations Grant Health Personnel Health Professional Health Sciences Home environment Individual Institutes Instruction Intervention Investments Laboratories Learning Massachusetts Medical Students Medicine Mentors Minority New England Nobel Prize Nurses Nursing Research Nursing Students Online Systems Patients Phase Physicians Physiology Postdoctoral Fellow Primary Health Care Process Program Development Public Health RNA Recruitment Activity Regenerative Medicine Research Research Personnel Research Support Research Training Resources Schedule Schools Scientist Seeds Site Speed Statutes and Laws Students Support System System Technology Therapeutic Therapeutic Intervention Training Programs Training and Education Translational Research Universities Unmarried person Work base bench to bedside biomedical informatics career career development design dissemination research effectiveness research experience flexibility gene therapy graduate student health care delivery implementation research innovation interdisciplinary approach medical schools population based programs simulation skills stem cell biology tool

项目摘要

We have established the University of Massachusetts Center for Clinical and Translational Science (UMCCTS) which includes the five UMass campuses. Operationally, the Center is located at the University's Worcester campus and managed by the School of Medicine. The Center serves as the "academic home" for clinical and translational scientists across all UMass campuses. The CTSA program will build clinical and translational research upon a foundation of world class basic science as evidenced by the award of the Nobel Prize in Physiology or Medicine to Craig Mello in 2006 and the Albeil Lasker Award to Victor Ambros in 2008. The UMCCTS aims are to: 1) Accelerate early phase translational (T1) studies by recruiting outstanding T1 research leaders; establishing innovative research core facilities; and developing new therapies, devices, and interventions based upon UMass discoveries; 2) Integrate unique networks of clinical research and healthcare delivery in Central New England and Massachusetts at-large to build and expand T2 (clinical effectiveness research) and T3 (implementation and dissemination research) capacity by recruiting outstanding T2 and T3 research leaders, and by developing innovative T2/T3 core facilities; and enhancing patient and community outreach and participation in clinical/population-based research; 3) The UMCCTS will work collaboratively with all campuses and schools ofthe UMass system in developing programs, curricula, and faculty support systems that promote careers in clinical and translational research. Governor Deval Patrick and the Massachusetts Legislature recently enacted legislation committing $1 billion in state investment to be directed to the Life Sciences in the Commonwealth. With $90 million in seed funding, the University has established the UMass Advanced Therapeutics Cluster (UMATC) which includes the RNA Therapeutics Institute, the Center for Stem Cell Biology and Regenerative Medicine, and the Gene Therapy Center. The UMATC joins the Massachusetts Biologic Laboratories, Meyers Primary Care Institute, and Commonwealth Medicine, four innovative components that are rarely found in academic centers, to speed bench to bedside to community discoveries in clinical and translational research. RELEVANCE (See instructions): The University of Massachusetts Center for Clinical and Translational Science (UMCCTS) will transform the conduct of clinical and translational research by providing an "academic home" for all university clinical investigators. The UMCCTS will provide robust pilot grant programs, comprehensive education and career development programs, and innovative core facilities to support and nurture clinical investigators.

我们建立了马萨诸塞大学临床和转化科学中心 (UMCCTS)，其中包括麻省大学的五个校区。在运营上，该中心位于大学的伍斯特校区并由医学院管理。该中心作为“学术之家” 麻省大学所有校区的临床和转化科学家。 CTSA 计划将建立临床和转化研究建立在世界级基础科学的基础上，这一点已被该奖项所证明克雷格·梅洛 (Craig Mello) 荣获 2006 年诺贝尔生理学或医学奖，维克多·安布罗斯 (Victor Ambros) 荣获阿尔贝尔·拉斯克奖 (Albeil Lasker Award) 2008 年。UMCCTS 的目标是： 1) 通过招募加速早期转化 (T1) 研究杰出的T1研究带头人；建立创新研究核心设施；并开发新的基于麻省大学发现的疗法、设备和干预措施； 2) 整合独特的临床网络在新英格兰中部和马萨诸塞州建立和扩大研究和医疗保健服务 T2（临床有效性研究）和T3（实施和传播研究）能力招募优秀的T2和T3研究带头人，开发创新的T2/T3核心设施；和加强患者和社区的外展活动以及对临床/人群研究的参与； 3) 的 UMCCTS 将与麻省大学系统的所有校区和学校合作开发促进临床和转化研究职业发展的项目、课程和教师支持系统。州长德瓦尔·帕特里克 (Deval Patrick) 和马萨诸塞州立法机构最近颁布了一项法案，承诺拨款 10 亿美元国家投资将直接用于英联邦的生命科学。拥有 9000 万美元的种子资金在资金的支持下，该大学建立了麻省大学先进治疗集群（UMATC），其中包括 RNA 治疗研究所、干细胞生物学和再生医学中心以及基因治疗中心。 UMATC 加入马萨诸塞州生物实验室、迈耶斯初级保健研究所、和联邦医学，这四个创新组成部分在学术中心很少见，加速临床和转化研究中从床边到社区的发现。相关性（参见说明）：马萨诸塞大学临床和转化科学中心 (UMCCTS) 将改变通过为所有大学临床提供“学术之家”来进行临床和转化研究调查人员。 UMCCTS 将提供强有力的试点资助计划、全面的教育和职业开发计划和创新核心设施来支持和培养临床研究人员。