Core Support for Cancer Center

癌症中心的核心支持

基本信息

批准号：
8847840
负责人：
Israel DAVID GOLDMAN
金额：
$ 7.5万
依托单位：
ALBERT EINSTEIN COLLEGE OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-06-01 至 2018-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8847840
关键词：
Address Advisory Committees Aging Albert Einstein Cancer Center Animals Area Basic Science Bioinformatics Biology Biometry Cancer Center Cancer Center Support Grant Cancer Etiology Clinical Clinical Research Colon Carcinoma Comparative Pathology Diagnosis Dimensions Epidemiology Evaluation Faculty Flow Cytometry Funding Gene Targeting Genetic Medicine Genomics Goals Grant Histology Image Indium Informatics Institutes Instruction Malignant Neoplasms Mission Molecular Cytogenetics Morbidity - disease rate National Institute of Diabetes and Digestive and Kidney Diseases Nature Neoplasm Metastasis Peer Review Grants Play Population Research Prevention approach Price Process Program Development Proteomics Protocols documentation Reporting Research Research Infrastructure Resource Allocation Resource Sharing Resources Role Signal Transduction Staging Stem cells Strategic Planning Structure Systems Biology Therapeutic Transgenic Organisms Translational Research biobank cancer epidemiology cancer research center director cancer stem cell cancer therapy college data management drug development improved meetings member mortality neoplasm resource novel strategies programs stem cell differentiation structural biology translational medicine tumor microenvironment

项目摘要

DESCRIPTION (provided by applicant): This application seeks renewed CCSG funding for year 40 of the Albert Einstein Cancer Center (AECC) which received its first NCI designation in 1972. There are five established programs, including: (i) Tumor Microenvironment and Metastasis, led by John Condeelis, (ii) Stem Cells, Differentiation and Cancer, led by Richard Stanley, (iii) Experimental Therapeutics led by Susan Horwitz and Roman Perez-Soler), (iv) Cancer Epidemiology led by Thomas Rohan, and (v) The Biology of Colon Cancer, led by Leonard Augenlicht. There are thirteen established shared resources including: Analytical Imaging, Animal Barrier, Bioinformatics, Biostatistics, Centralized Protocol & Data Management Unit (CPDMU), Epidemiology Informatics, Flow Cytometry, Gene Targeting & Transgenic, Genomics, Histology and Comparative Pathology, Molecular Cytogenetic, Proteomics, and Structural Biology. Funding is requested for one new shared resource, Cancer Biospecimen Acquisition and Biorepository. In 2008, a major new research building was opened, the Price Center/Block Pavilion for Genetic and Translational Medicine, with more than half of that facility now occupied by AECC members and shared resources. An Einstein Stem Cell Institute was recently established adding a new dimension to the AECC research portfolio. There are currently 153 full AECC members. AECC research is supported by 82 NCI grants ($18.6 million direct) and 103 other cancer relevant peer-reviewed grants ($30.3 million direct).

描述（由申请人提供）：本申请为阿尔伯特·爱因斯坦癌症中心 (AECC) 的第 40 年寻求更新的 CCSG 资助，该中心于 1972 年首次获得 NCI 指定。有五个既定项目，包括：(i) 肿瘤微环境和转移，由 John Condeelis 领导，(ii) 干细胞、分化和癌症，由 Richard Stanley 领导，(iii) 实验治疗学，由 Susan Horwitz 和 Roman 领导Perez-Soler），(iv) 由 Thomas Rohan 领导的癌症流行病学，以及 (v) 由 Leonard Augenlicht 领导的结肠癌生物学。有十三个已建立的共享资源，包括：分析成像、动物屏障、生物信息学、生物统计学、集中协议和数据管理单元（CPDMU）、流行病学信息学、流式细胞术、基因靶向和转基因、基因组学、组织学和比较病理学、分子细胞遗传学、蛋白质组学和结构生物学。需要为一项新的共享资源“癌症生物样本采集和生物样本库”提供资金。 2008 年，一座重要的新研究大楼落成，即遗传和转化医学价格中心/街区馆，该设施的一半以上现在由 AECC 成员占用并共享资源。爱因斯坦干细胞研究所最近成立，为 AECC 的研究组合增添了新的维度。目前 AECC 正式会员 153 名。 AECC 研究得到 82 项 NCI 拨款（直接 1,860 万美元）和 103 项其他癌症相关同行评审拨款（直接 3,030 万美元）的支持。