Ghana Cancer Registry - from Hospital to Population: a Pilot Study

加纳癌症登记处 - 从医院到人群：试点研究

• 批准号: 8958748
• 负责人: Ann Hsing
• 金额: $ 4.26万
• 依托单位: CANCER PREVENTION INSTIT OF CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-15 至 2016-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8958748
• 关键词: Address; Affect; Africa; African; African American; Archives; Area; Awareness; Biological Markers; California; Cancer Burden; Cancer Control; Capital; Caring; Case Study; Centers for Disease Control and Prevention (U.S.); Cities; Clinical; Clinical Data; Clinical Management; Colon; Communicable Diseases; Country; Data; Data Quality; Developing Countries; Diagnosis; Diagnostic; Educational workshop; Future; Genetic; Ghana; Goals; Health care facility; Hospitals; Incidence; Institute for Cancer Prevention; International; International Agency for Research on Cancer; Kidney; Life Expectancy; Link; Lung; Malignant Neoplasms; Malignant neoplasm of prostate; Medical Surveillance; Mission; Molecular; Monitor; National Cancer Institute; Normal tissue morphology; Pathology; Pattern; Persons; Pilot Projects; Population; Population Growth; Population-Based Registry; Positioning Attribute; Prevention; Procedures; Process; Prostate; Provider; Records; Registries; Research; Research Infrastructure; Research Training; Resources; Retrieval; SEER Program; Specimen; Surveys; Teaching Hospitals; Tissue Banking; Tissue Banks; Training; Tumor Biology; Tumor Tissue; Universities; anticancer research; base; burden of illness; cancer prevention; case finding; data registry; disability; disorder prevention; improved; insight; interest; malignant breast neoplasm; medical schools; meetings; metropolitan; neoplasm registry; operation; population based; public health relevance; surveillance data; trend; tumor; willingness

 DESCRIPTION (provided by applicant): Although communicable diseases still represent the major disease burden in Africa, clinical data suggest that cancer incidence is increasing rapidly in Africa and at a rate that is faster than that in the developed world. There is also evidence tha "Western cancers," including cancers of the breast, prostate, colon, and lung, are becoming very common in many African countries. However, just 1% of the continent's population is covered by population-based registries (in the US, 28% of the population is covered by NCI's Surveillance, Epidemiology, and End Results Program and 83% from all state registries combined). The lack of population- based cancer surveillance data makes it difficult to quantify the exact burden of cancer in Africa and develop effective strategies for cancer prevention and control. To help address the need for developing population- based registries to provide information to guide cancer prevention and control efforts, the Cancer Prevention Institute of California (CPIC) is partnering with the University of Ghana Medical School (UGMS), Korle Bu Teaching Hospital (KBTH; a UGMS-affiliated hospital), and the African Cancer Registry Network (AFCRN; a partner of the International Agency for Research on Cancer) to develop a demonstration pilot cancer registration project in Accra, the capital city of Ghana. As a first ste towards an Accra population-based cancer registry, we propose to establish a hospital-based cancer registry at KBTH. KBTH is the largest hospital in the Accra metropolitan area and serves about two-thirds of the Accra population (70% coverage is considered population-based by the AFCRN). The cancer registry developed at KBTH is expected to become the Center for Excellence in Cancer Registration in Ghana, and to be a training center for extending cancer registration to other hospitals in Accra to enhance population coverage beyond 70%. This proposed study will establish effective procedures and training for KBTH-wide active case finding for cancer cases diagnosed in 2014-2015, and for active case reporting for cancer cases diagnosed in 2016-2017 (Aim 1). We will also develop procedures to link the cancer registry with KBTH's tumor archives to create a registry-linked tissue bank that can be used for efficient retrieval of pathology materials for future molecular studies (Aim 2). Finally, we will survey othe hospitals in Accra to assess their willingness to contribute cancer data to a population- based cancer registry (Aim 3). We will hold a workshop on cancer registration and provide training to providers on the importance of cancer registration to help increase awareness and interest in cancer registration. Successful completion of our aims will pave the way for a future population-based registry in Accra that will generate high-quality surveillance data to aid the effort of cancr prevention and control in Ghana. The Ghana registry data can be compared with cancer patterns among African Americans to clarify why persons of African descent are disproportionally affected by certain cancers, such as cancers of the prostate and kidney.

 描述（由适用提供）：尽管传播性疾病仍然代表着非洲的主要疾病燃烧，但临床数据表明，非洲的癌症发病率正在迅速增加，并且速度比发达国家快的速度更快。也有证据表明，包括乳房，前列腺，结肠和肺在内的“西方癌症”在许多非洲国家都变得非常普遍。但是，只有1％的继续人口涵盖了基于人群的注册机构（在美国，28％的人口受NCI的监视，流行病学和最终结果计划的涵盖，所有州注册表的总和为83％）。缺乏基于人群的癌症监测数据使得很难量化非洲癌症的确切燃烧，并制定了预防癌症和控制的有效策略。为了帮助满足开发基于人群的注册服务以指导癌症预防和控制工作的需求，加利福尼亚癌症预防研究所（CPIC）与加纳大学医学院（UGMS），Korle BU教学医院（KBTH； UGMS相关医院）和非洲癌症登机企业的癌症竞赛（AFCRN）竞赛（AFCRN）合作，以癌症的范围； 加纳。作为迈向基于ACCRA的癌症注册中心的第一个Ste，我们建议在KBTH建立基于医院的癌症注册表。 KBTH是阿克拉都会区最大的医院，为阿克拉人口的约为三分之二（70％的覆盖范围被AFCRN认为是基于人口的70％）。 KBTH开发的癌症登记处有望成为加纳癌症注册卓越的中心，并成为将癌症注册扩展到阿克拉其他医院的培训中心，以将人口覆盖率提高到70％以上。这项拟议的研究将针对2014 - 2015年诊断为诊断的癌症病例的KBTH范围内的活动病例发现有效的程序和培训，并针对2016 - 2017年诊断的癌症病例的活动病例报告（AIM 1）。我们还将开发程序，将癌症注册表与KBTH的肿瘤档案联系起来，以创建注册表连接的组织库，该组织可用于有效检索未来分子研究的病理材料（AIM 2）。最后，我们将调查或阿克拉的医院评估他们为基于人群的癌症注册表提供癌症数据的意愿（AIM 3）。我们将举办有关癌症注册的研讨会，并向提供者提供有关癌症注册对有助于提高认识和癌症注册兴趣的重要性的培训。成功完成我们的目标将为未来的Accra注册中心铺平道路，该注册表将产生高质量的监视数据，以帮助加纳的CANCR预防和控制。可以将加纳注册表的数据与非裔美国人的癌症模式进行比较，以澄清为什么非洲血统的人会受到某些癌症的影响，例如前列腺和肾脏的癌症。