Research Training Program in Basic and Translational Oncology

基础和转化肿瘤学研究培训计划

• 批准号: 8904635
• 负责人: PRAN K DATTA
• 金额: $ 19.33万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-05 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8904635
• 关键词: Research Training; Training Programs; oncology

DESCRIPTION (provided by applicant): The multidisciplinary UAB "Research Training Program in Basic and Translational Oncology" is focused on training highly motivated pre-doctoral students as well as PhD and MD graduates in the fields of translational and fundamental oncology. Major strengths of the program include the broad expertise and research interests of its faculty, encompassing tumor immunology, cancer genetics, mouse models of cancers, statistical genetics, next-generation sequencing of various cancers, preclinical models of novel targeted therapies, as well as phase 1 and phase 2 clinical studies. In the first year two postdoctoral trainees will be selected from the hematology/oncology fellowship program and among a large pool of postdoctoral fellows conducting oncology research at UAB. Their training will last up to three years. The training program will grow into three postdoctoral fellows and one pre-doctoral student by year two and three of the five year training program, respectively. The postdoctoral trainees with a MD, PhD or equivalent terminal degree will be selected on the basis of prior academic and research performance, letters of recommendations, and personal interviews. This will include highly qualified students from the Medical Scientist Training Program. While this is a new application, UAB had an active hematology research training program from 1991 until 2004 when the former cancer center director and the former division of hematology/oncology director resigned. A new cancer center director was appointed in 2007 and a new director of the division of hematology/oncology was appointed in 2008. Under this new leadership a large number of well-funded investigators with a focus on cancer research have been hired and strengthen an already very strong core of oncology researchers. Because a large number of the faculty members is involved in the care of patients with a diagnosis of cancer in addition to their research programs, the program offers an optimal interface between basic and applied oncology.

描述（由申请人提供）：多学科的UAB“基本和转化肿瘤学研究培训计划”的重点是培训较高动机的博士前学生以及转化和基本肿瘤学领域的博士学位和MD毕业生。该计划的主要优势包括其教职员工的广泛专业知识和研究兴趣，包括肿瘤免疫学，癌症遗传学，癌症的小鼠模型，统计遗传学，各种癌症的下一代测序，新型靶向疗法的临床前模型，以及第1期和第2阶段和第2阶段临床研究。在第一年两年 博士后学员将从血液学/肿瘤学奖学金计划中选出，以及在UAB进行肿瘤研究的大量博士后研究员中。他们的培训将持续长达三年。培训计划将成长为三个博士后研究员，一个 分别在五年培训计划的二年级和三年级的学生前学生。将根据先前的学术和研究表现，推荐信和个人访谈的基础选择拥有医学博士，博士或同等终端学位的博士后学员。这将包括来自医学科学家培训计划的高素质学生。虽然这是一个新的应用程序，但UAB从1991年到2004年就进行了一项积极的血液学研究培训计划，届时癌症中心主任和前血液学/肿瘤学主任的前部辞职。 2007年任命了一名新的癌症中心主任，并于2008年任命了血液学/肿瘤学系的新主管。在这一新领导下，聘请了大量资金丰富的研究人员，重点是癌症研究，并增强了已经非常强大的肿瘤学研究人员的核心。由于大量教职员工除了研究计划外，还参与了诊断癌症患者的护理，因此该计划在基本肿瘤学和应用肿瘤学之间提供了最佳的接口。