Training Prgm in Inflammatory and Immunological Diseases

炎症和免疫疾病培训项目

• 批准号: 8669903
• 负责人: DAVID STEPHEN PISETSKY
• 金额: $ 21.66万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1980
• 资助国家: 美国
• 起止时间: 1980-09-30 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8669903
• 关键词: Immune System Diseases; Inflammatory; Training

DESCRIPTION (provided by applicant): The goal of the Training Program in Inflammatory and Immunological Disease (T32 AI07217) at the Duke University Medical Center (DUMC) is to train outstanding individuals to pursue independent careers in research relevant to 1) the pathogenesis of rheumatologic and immunologic diseases in children and adults and 2) the translation of new knowledge on disease mechanisms into innovative approaches to diagnosis, treatment or prevention of disease. These individuals may hold the M.D., M.D./Ph.D. or Ph.D. degrees and will gain specialized training to work at the interface of clinical and basic research; to utilize state of the art molecular, genetic and genomic approaches to develop new immunomodulatory agents and understand their mechanisms of action; and to manage complex datasets to develop better predictors of disease prognosis and response to treatment. As such, these individuals will be uniquely suited to advancing the goal of personalized medicine in the treatment of immune-mediated diseases. Importantly, this program will address the critical need for investigators conducting innovative research in inflammatory and immunological diseases in patients of all ages. We propose, through the continuation of our ongoing training program, to train individuals who can meet the challenge of modern biomedicine and have unique skills to participate in investigative teams in the full spectrum of "bench to bedside" research, ranging from fundamental laboratory research to clinical and epidemiological studies. This program will be highly interdisciplinary and interactive, encompassing both adult and pediatric rheumatology. Importantly, this program will emphasize collaboration and team approaches. Dr. David Pisetsky, Professor of Medicine and Immunology at DUMC and Chief of Rheumatology at the Durham Veterans Administration Medical Center (VAMC), will serve as Director while Dr. Laura Schanberg, Professor of Pediatrics and Co-Chief of Pediatric Rheumatology, will serve as Co-Director. To promote its activities, the training program incorporates a core of investigators from the Divisions of Rheumatology in the Departments of Medicine and Pediatrics as well as a talented and diverse coterie of researchers in other clinical as well as basic science departments. This proposal builds on a long history of successful training programs in adult and pediatric rheumatology and immunology at the DUMC; the existing highly effective and productive collaboration between the divisions in both training and research; and strong institutional support from both clinical departments as well as the Department of Immunology.

描述（由申请人提供）：在炎症和免疫疾病中培训计划的目标（T32 AI07217）在杜克大学医学中心（DUMC）旨在培训杰出的个人从事与儿童和成人疾病的疾病的疾病的疾病有关的研究，从而从事独立的研究。 疾病。这些人可以持有医学博士，医学博士/ph.d。或博士学位学位并将获得专门的培训，以在临床和基础研究的界面上工作；利用艺术分子，遗传和基因组方法的状态来开发新的免疫调节剂并了解其作用机理；并管理复杂的数据集，以开发更好的疾病预后预测指标和对治疗的反应。因此，这些人将非常适合促进个性化医学治疗免疫介导疾病的目标。重要的是，该计划将解决各个年龄段患者进行炎症和免疫疾病创新研究的研究人员的关键需求。我们建议通过持续正在进行的培训计划的继续培训可以满足现代生物医学挑战的个人，并具有独特的技能，可以参与整个“长凳到床边”研究的调查团队，从基本实验室研究到临床和流行病学研究。该计划将是高度跨学科和互动性的，涵盖了成人和小儿风湿病学。重要的是，该计划将强调协作和团队方法。 DUMC医学和免疫学教授David Pisetsky博士，达勒姆退伍军人管理局医疗中心（VAMC）的风湿病学主任，将担任主任，而儿科和儿科研究学教授Laura Schanberg博士将担任共同主管。为了促进其活动，该培训计划融合了医学和儿科部门风湿病学部门的调查人员的核心，以及其他临床和基础科学部门的才华横溢且多样化的研究人员。该提议建立在DUMC成人和小儿风湿病学和免疫学方面成功培训计划的悠久历史；现有的培训和研究部门之间的高效和富有成效的合作；以及临床部门以及免疫学系的强大机构支持。