Dealing with missing data in HIV prevention trials

处理艾滋病毒预防试验中缺失的数据

基本信息

批准号：
8246512
负责人：
Ofer Harel
金额：
$ 17.97万
依托单位：
UNIVERSITY OF CONNECTICUT STORRS
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-04-09 至 2015-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8246512
关键词：
AIDS prevention AIDS/HIV problem Accounting Acquired Immunodeficiency Syndrome Acyclovir Adult African African American Age Alcohol or Other Drugs use Alcohols American Attention Behavior Therapy Behavioral Behavioral Research Biological Biometry Cause of Death Centers for Disease Control and Prevention (U.S.)Cities Clinical Communities Complication Counseling Country Cross-Over Studies Data District of Columbia Double-Blind Method Drops Effectiveness Ensure Epidemic Funding Future Goals Guidelines HIV HIV Infections HIV Seropositivity HIV prevention trial HIV prevention trials network HIV-1 Health Healthcare Human Herpesvirus 2 Infection Intention International Intervention Intervention Studies Investigation Lead Learning Life Literature Longevity Longitudinal Studies Los Angeles Measures Medical Mentored Research Scientist Development Award Methodology Methods Mission NIH Program Announcements National Institute of Mental Health New York Persons Pharmaceutical Preparations Placebo Control Plague Population Positioning Attribute Pre-Post Tests Prevention Prevention Research Prevention program Preventive Intervention Procedures Process Quality of life Ramp Randomized Randomized Clinical Trials Research Research Design Research Personnel Risk Risk Behaviors Risk Reduction Sampling San Francisco Science Scientist Simplexvirus Site South Africa Techniques Testing Training United States United States National Institutes of Health Variant Visit Woman Writing base design effective intervention genital herpes high risk improved intravenous drug use men men who have sex with men prevent public health relevance response sex sexually active simulation social statistics tool transmission process treatment effect valacyclovir

项目摘要

DESCRIPTION (provided by applicant): HIV/AIDS has been an international crisis for decades. All current research suggests that there is not likely to be any medical cure anytime soon, and that prevention is the best strategy that we can employ. However, notwithstanding that HIV/AIDS prevention has been the goal and primary focus of funding internationally for decades, we still see a sharp increase in the number of new HIV/AIDS cases across the globe annually. Clearly, there needs to be more focus and research dedicated to ensuring that we are using the best prevention techniques possible. My long term goal is to develop new methodologies for advancing clinical and community AIDS behavioral research. In addition, my aim is to develop new methods that will lead to enhanced HIV prevention interventions. This application supports the mission of the National Institute of Mental Health by providing methodologies for incomplete data, this will be used to help develop effective interventions and by providing training to position this candidate to engage in future research to improve the HIV prevention. PUBLIC HEALTH RELEVANCE: HIV/AIDS has been an international crisis for decades. All current research suggests that there is not likely to be any medical cure anytime soon, and that prevention is the best strategy that we can employ. My long term goal is to develop new methodologies for advancing clinical and community AIDS behavioral research. In addition, my aim is to develop new methods that will lead to enhanced HIV prevention interventions, In particular, methods to deal with incomplete data.

描述（由申请人提供）：数十年来，艾滋病毒/艾滋病一直是一场国际危机。目前的所有研究都表明，短期内不太可能有任何药物治愈，预防是我们可以采取的最佳策略。然而，尽管几十年来预防艾滋病毒/艾滋病一直是国际资助的目标和主要重点，但我们仍然看到全球每年新发艾滋病毒/艾滋病病例数急剧增加。显然，需要更多的关注和研究，以确保我们使用尽可能最好的预防技术。我的长期目标是开发新的方法来推进临床和社区艾滋病行为研究。此外，我的目标是开发新方法，以加强艾滋病毒预防干预措施。该应用程序通过提供不完整数据的方法来支持国家心理健康研究所的使命，这将用于帮助制定有效的干预措施，并提供培训以使该候选人能够参与未来的研究以改善艾滋病毒的预防。公共卫生相关性：几十年来，艾滋病毒/艾滋病一直是一场国际危机。目前的所有研究都表明，短期内不太可能有任何药物治愈，预防是我们可以采取的最佳策略。我的长期目标是开发新的方法来推进临床和社区艾滋病行为研究。此外，我的目标是开发新方法，以加强艾滋病毒预防干预措施，特别是处理不完整数据的方法。