Duke CTSA (Composite)

杜克 CTSA（复合）

• 批准号: 8743359
• 负责人: Leigh E Boulware
• 金额: $ 35.53万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-26 至 2018-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8743359
• 关键词: Biometry; Clinical Research; Clinical Trials; Communities; Development; Discipline; Disease; Education; Electronic Health Record; Ensure; Environment; Ethics; Fostering; Funding; Goals; Health Sciences; Health Services; Health system; Home environment; Human; Information Technology; Instruction; Learning; Link; Mentors; Outcome; Patients; Process; Productivity; Registries; Research; Research Infrastructure; Research Personnel; Resources; Safety; Schools; Science; Site; System; Training; Training Programs; Translational Research; Translations; Update; Vision; base; bench to bedside; biobank; cost; cost effectiveness; implementation science; improved; innovation; medical specialties; multi-site trial; new technology; next generation; population based; systems research; tool

To fulfill the new NCATS vision for the CTSA Consortium and accelerate scientific discoveries into improved outcomes for patients, academic health and science systems must invest, transform, and innovate to optimize their unique strengths. Our vision, aligned with that of NCATS, is to create a research environment at Duke that stimulates the translation of scientific discovery from bench to bedside by 1) linking discovery science to a creative engine that efficiently accelerates development of new technologies; and 2) integrating clinical trials, registries, and electronic health records in a learning health system where research and practice form a continuum. Our research environment will be driven by scientific merit and societal need, "agnostic" to disease or specialty discipline, aligned with our updated institutional framework for research oversight and quality, and continually evaluated for academic productivity, efficiency, and cost. To achieve these goals, we will create an Integrated Home for clinical and translational research by providing infrastructure and resources to serve investigators and trainees across the research spectrum. We will offer resources based upon common needs among our researchers, including education, biostatistics, biobanking, regulatory expertise, ethics, pilot funding and recruitment assistance. We will also tailor our offerings to specialized needs across research communities that include early translation, proof of concept, site-based research and population based research, which includes multi-site trials, outcomes, health services, implementation science and community engaged research. Integrating these resources will require a new tool, a portal for all trainees and investigators, MyResearchHome(@Duke, and its human counterpart, MyResearchTeam@Duke. These tools will provide a single point of entry for all clinical and translational research at Duke, regardless of their department or school. Thus, we will enhance our Integrated Home for clinical and translational research with a combination of sophisticated information technology and mentoring and navigation; provide access to common and specialized resources for all of our translational research communities and train the next generation of researchers in our educational and training programs. RELEVANCE (See instructions): The CTSA will foster the translational research process, ensuring that new discoveries are developed and evaluated more quickly and that clinical research is done with high quality, efficiency, safety and cost- effectiveness.

为了实现CTSA财团的新NCAT愿景，并加速了科学发现 患者，学术健康和科学系统的成果必须投资，转变和创新 优化其独特的优势。我们的愿景与NCAT的愿景是为了创建一个研究环境 在杜克 科学到有效加速新技术开发的创意引擎； 2）整合 在学习健康系统中的临床试验，注册表和电子健康记录 练习形成连续性。我们的研究环境将由科学的优点和社会需求驱动， 对疾病或专业学科的“不可知论”，与我们最新的研究框架保持一致 监督和质量，并不断评估学术生产力，效率和成本。实现 这些目标，我们将通过提供临床和翻译研究的综合房屋 基础设施和资源为研究范围内的研究人员和学员提供服务。我们将提供 基于我们的研究人员共同需求的资源，包括教育，生物统计学，生物群， 监管专业知识，道德，试点资金和招聘援助。我们还将定制我们的产品 整个研究社区的专业需求，包括早期翻译，概念证明，基于网站 基于研究和人群的研究，包括多站点试验，结果，健康服务， 实施科学和社区参与研究。整合这些资源将需要一个新的 工具，所有受训人员和调查员的门户，MyResearchHome（@Duke及其人类对应物， myResearchTeam@duke。这些工具将为所有临床和翻译提供一个单一的入学点 在杜克大学的研究，无论他们的部门或学校如何。因此，我们将改善我们的综合房屋 临床和翻译研究结合了复杂的信息技术和指导 和导航；为我们所有的翻译研究提供通用和专业资源的访问 社区和培训下一代研究人员在我们的教育和培训计划中。 相关性（请参阅说明）： CTSA将促进转化研究过程，确保开发新发现并 更快地评估了临床研究，以高质量，效率，安全性和成本 - 效力。