Hawaii Asian and Pacific Islander Diabetes Study

夏威夷亚洲和太平洋岛民糖尿病研究

• 批准号: 8696853
• 负责人: Beth E. Waitzfelder
• 金额: $ 66.59万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-15 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8696853
• 关键词: Acculturation; Address; Age; American Heart Association; Asian Americans; Asians; Body mass index; Cardiovascular Diseases; Caucasians; Caucasoid Race; Censuses; Chinese People; Clinical; Comorbidity; Complications of Diabetes Mellitus; Computerized Medical Record; Data; Diabetes Mellitus; Diet; Environmental Risk Factor; Ethnic Origin; Filipino; Goals; Hawaii; Hawaiian population; Health behavior; Health system; High Prevalence; Individual; Integrated Health Care Systems; Intervention; Japanese Population; Knowledge; Lower Extremity; Masks; Minority; Myocardial Infarction; Not Hispanic or Latino; Outcome; Pacific Island Americans; Patient Self-Report; Patients; Pattern; Peripheral Vascular Diseases; Population; Population Heterogeneity; Population Sizes; Population Study; Prevalence; Provider; Race; Research; Research Design; Risk Factors; Samoan; Science; Series; Smoking; Socioeconomic Status; Stroke; Subgroup; Surveys; Treatment Factor; United States; Ursidae Family; clinical care; design; effective intervention; evidence base; health care service organization; health disparity; high risk; improved; public health relevance; sex

DESCRIPTION (provided by applicant): Asians and Pacific Islanders as a whole bear a disproportionate burden of diabetes, both in terms of higher prevalence and rates of diabetes-related complications. Asian and Pacific Islander populations are the fastest growing populations in the United States (US), increasing by 43 percent and 35 percent respectively during the past decade. Despite obvious and important differences among Asian and Pacific Islander subgroups, the relatively small size of these populations included in diabetes studies has resulted in the "lumping" of these heterogeneous populations of Asian groups and Pacific Islanders in diabetes studies, masking potentially important differences. The study of these groups is also complicated by a relatively high proportion of individuals with mixed race/ethnicity. As a consequence, little is known about diabetes prevalence, treatment patterns and outcomes among Asian and Pacific Islander (API) populations, or importantly, about underlying factors contributing to differences among these populations. Diabetes prevalence, and particularly outcomes, is influenced by many individual, treatment and environmental factors. The objective of this study is to utilize electronic medical record (EMR) data, patient survey data and geocoded census data to comprehensively assess differences in diabetes prevalence, intermediate clinical outcomes and prevalence of diabetes-related complications among ten well-defined populations in a large integrated health care system in Hawaii. The ten populations studied will include: Japanese; Chinese; Filipino, Hawaiians; Samoans; mixed Asian+Caucasian; mixed Asian+Hawaiian; mixed Hawaiian and Caucasian; and mixed Asian+Hawaiian+Caucasian. A Caucasian-only group will also be included for purposes of comparison. The study will focus on a series of variables known to be important influences in diabetes prevalence and outcomes in each of three broad domains: individual factors; treatment factors; and environmental factors. The specific aims of the study are to: 1. Describe differences in diabetes prevalence, intermediate clinical outcomes and complications among these Asian and Pacific Islander populations; and 2. Identify the most important contributing factors to observed differences among these populations within a series of individual, treatment and environmental factors. The results of this study will provide important information about the underlying causes of disparities among a rapidly growing segment of the US population, with findings potentially relevant to other minority populations, and have practical utility in the strategic design of targeted interventions to achieve optimal outcomes for diabetes among Asian and Pacific Islander populations.

描述（由申请人提供）：亚洲人和太平洋岛民作为一个整体，承受着不成比例的糖尿病负担，无论是在较高的患病率还是糖尿病相关并发症的发生率方面。亚洲和太平洋岛民人口是美国增长最快的人口，在过去十年中分别增长了 43% 和 35%。尽管亚洲和太平洋岛民亚群体之间存在明显且重要的差异，但糖尿病研究中纳入的这些人群规模相对较小，导致糖尿病研究中亚洲群体和太平洋岛民的这些异质人群“集中”，掩盖了潜在的重要差异。对这些群体的研究也因混血/民族个体比例相对较高而变得复杂。因此，人们对亚洲和太平洋岛民 (API) 人群的糖尿病患病率、治疗模式和结果知之甚少，更重要的是，对导致这些人群之间差异的潜在因素知之甚少。 糖尿病患病率，特别是结果，受到许多个人、治疗和环境因素的影响。本研究的目的是利用电子病历 (EMR) 数据、患者调查数据和地理编码的人口普查数据，全面评估大型地区 10 个明确人群中糖尿病患病率、中间临床结果和糖尿病相关并发症患病率的差异。夏威夷的综合医疗保健系统。研究的十个人群包括： 日本人；中国人;菲律宾人、夏威夷人；萨摩亚人；亚洲+高加索混血；亚洲+夏威夷混血；夏威夷和高加索混血；以及亚洲人+夏威夷人+高加索人的混合血统。出于比较目的，还将包括仅白人群体。该研究将重点关注已知对糖尿病患病率和结果产生重要影响的一系列变量，涉及三个广泛领域：个体因素；治疗因素；和环境因素。该研究的具体目的是： 1. 描述这些亚洲和太平洋岛民人群中糖尿病患病率、中间临床结果和并发症的差异； 2. 在一系列个体、治疗和环境因素中确定这些人群之间观察到的差异的最重要影响因素。 这项研究的结果将提供关于快速增长的美国人口中差异的根本原因的重要信息，其研究结果可能与其他少数族裔相关，并且对于有针对性的干预措施的战略设计具有实际用途，以实现最佳结果亚洲和太平洋岛民人群中的糖尿病。