Hawaii Asian and Pacific Islander Diabetes Study

夏威夷亚洲和太平洋岛民糖尿病研究

• 批准号: 8504881
• 负责人: Beth E. Waitzfelder
• 金额: $ 54.51万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-15 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8504881
• 关键词: Acculturation; Address; Age; American Heart Association; Asian Americans; Asians; Body mass index; Cardiovascular Diseases; Caucasians; Caucasoid Race; Censuses; Chinese People; Clinical; Comorbidity; Complications of Diabetes Mellitus; Computerized Medical Record; Data; Diabetes Mellitus; Diet; Environmental Risk Factor; Ethnic Origin; Filipino; Goals; Hawaii; Hawaiian population; Health behavior; Health system; High Prevalence; Individual; Integrated Health Care Systems; Intervention; Japanese Population; Knowledge; Lower Extremity; Masks; Minority; Myocardial Infarction; Not Hispanic or Latino; Outcome; Pacific Island Americans; Patient Self-Report; Patients; Pattern; Peripheral Vascular Diseases; Population; Population Heterogeneity; Population Sizes; Population Study; Prevalence; Provider; Race; Research; Research Design; Risk Factors; Samoan; Science; Series; Smoking; Socioeconomic Status; Stroke; Subgroup; Surveys; Treatment Factor; United States; Ursidae Family; clinical care; design; effective intervention; evidence base; health care service organization; health disparity; high risk; improved; public health relevance; sex

DESCRIPTION (provided by applicant): Asians and Pacific Islanders as a whole bear a disproportionate burden of diabetes, both in terms of higher prevalence and rates of diabetes-related complications. Asian and Pacific Islander populations are the fastest growing populations in the United States (US), increasing by 43 percent and 35 percent respectively during the past decade. Despite obvious and important differences among Asian and Pacific Islander subgroups, the relatively small size of these populations included in diabetes studies has resulted in the "lumping" of these heterogeneous populations of Asian groups and Pacific Islanders in diabetes studies, masking potentially important differences. The study of these groups is also complicated by a relatively high proportion of individuals with mixed race/ethnicity. As a consequence, little is known about diabetes prevalence, treatment patterns and outcomes among Asian and Pacific Islander (API) populations, or importantly, about underlying factors contributing to differences among these populations. Diabetes prevalence, and particularly outcomes, is influenced by many individual, treatment and environmental factors. The objective of this study is to utilize electronic medical record (EMR) data, patient survey data and geocoded census data to comprehensively assess differences in diabetes prevalence, intermediate clinical outcomes and prevalence of diabetes-related complications among ten well-defined populations in a large integrated health care system in Hawaii. The ten populations studied will include: Japanese; Chinese; Filipino, Hawaiians; Samoans; mixed Asian+Caucasian; mixed Asian+Hawaiian; mixed Hawaiian and Caucasian; and mixed Asian+Hawaiian+Caucasian. A Caucasian-only group will also be included for purposes of comparison. The study will focus on a series of variables known to be important influences in diabetes prevalence and outcomes in each of three broad domains: individual factors; treatment factors; and environmental factors. The specific aims of the study are to: 1. Describe differences in diabetes prevalence, intermediate clinical outcomes and complications among these Asian and Pacific Islander populations; and 2. Identify the most important contributing factors to observed differences among these populations within a series of individual, treatment and environmental factors. The results of this study will provide important information about the underlying causes of disparities among a rapidly growing segment of the US population, with findings potentially relevant to other minority populations, and have practical utility in the strategic design of targeted interventions to achieve optimal outcomes for diabetes among Asian and Pacific Islander populations.

描述（由申请人提供）：在较高的患病率和与糖尿病相关的并发症的患病率和比率方面亚洲和太平洋岛民人口是美国增长最快的人口（美国），在过去的十年中，亚洲人的人口分别增加了43％和35％。尽管亚洲和太平洋岛民亚组之间存在明显且重要的差异，但糖尿病研究中包括的这些人群相对较小，导致亚洲群体和太平洋岛民研究中这些异质种群的“大量”在糖尿病研究中掩盖了潜在的重要差异。这些群体的研究也使相对较高的混合种族/种族个体比例相对较高。结果，关于糖尿病患病率，亚洲和太平洋岛民（API）人群的治疗模式和结果，或重要的是，关于导致这些人群差异的潜在因素，知之甚少。 糖尿病患病率，尤其是结果，受许多个人，治疗和环境因素的影响。这项研究的目的是利用电子病历（EMR）数据，患者调查数据和地理编码数据，以全面评估糖尿病患病率的差异，中间临床结果以及糖尿病相关并发症在夏威夷大型整体保健系统中十个良好定义的人群中与糖尿病相关的并发症的普遍性。研究的十个人群将包括：日语；中国人;夏威夷菲律宾人；萨摩亚人；亚洲+高加索人混合；亚洲混合+夏威夷人；夏威夷和高加索人混合；和混合亚洲+夏威夷+高加索人。仅出于比较的目的，还将包括一个仅白人组的组。该研究将集中于一系列已知的变量，这些变量已知是糖尿病患病率和三个广泛领域中每一个的结果的重要影响：个体因素；治疗因素；和环境因素。该研究的具体目的是：1。描述这些亚洲和太平洋岛民种群中糖尿病患病率，中间临床结局和并发症的差异；和2。确定一系列个体，治疗和环境因素中这些人群之间观察到的差异的最重要因素。 这项研究的结果将提供有关在美国人口迅速增长的一部分中差异的基本原因的重要信息，并可能与其他少数民族人群有关，并在有针对性的干预措施的战略设计方面具有实际实用性，以实现亚洲和太平洋岛民种群中糖尿病的最佳结果。