YOGA LIFESTYLE INTERVENTION REDUCES BLOOD PRESSURE IN HIV-INFECTED ADULTS

瑜伽生活方式干预可降低感染艾滋病毒的成年人的血压

• 批准号: 8361436
• 负责人: KEVIN E YARASHESKI
• 金额: $ 1.47万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361436
• 关键词: Adult; Blood Pressure; Body Composition; CD4 Positive T Lymphocytes; Cardiovascular Diseases; Cell Count; Control Groups; Equipment and supply inventories; Fasting; Funding; Grant; HIV; HIV Infections; Insulin; Life; Lipids; Lipoproteins; Mass Spectrum Analysis; Measures; Medical; Monitor; National Center for Research Resources; OGTT; Outcome Study; Plasma; Principal Investigator; Quality of life; RNA; Randomized Controlled Trials; Relative (related person); Research; Research Infrastructure; Resources; Rest; Risk; Risk Factors; Serum; Source; United States National Institutes of Health; Yoga; biomedical resource; cardiovascular disorder risk; cost; effective intervention; health related quality of life; immunological status; improved; lifestyle intervention; prospective; standard of care

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. OBJECTIVE: People living with HIV infection are at increased risk for developing cardiovascular disease (CVD). Safe and effective interventions for lowering CVD risk in HIV infection are high priorities. We conducted a prospective, randomized, controlled study to evaluate whether a yoga lifestyle intervention improves CVD risk factors, virological or immunological status, or quality of life (QOL) in HIV-infected adults relative to standard of care treatment in a matched control group. METHODS: Sixty HIV-infected adults with mild-moderate CVD risk were assigned to 20 weeks of supervised yoga practice or standard of care treatment. Baseline and week 20 measures were: 2-h oral glucose tolerance test with insulin monitoring, body composition, fasting serum lipid/lipoprotein profile, resting blood pressures, CD4 T-cell count and plasma HIV RNA, and the Medical Outcomes Study Short Form (SF)-36 health-related QOL inventory.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 目的：艾滋病毒感染者患心血管疾病（CVD）的风险增加。降低艾滋病毒感染者的心血管疾病风险的安全有效的干预措施是当务之急。我们进行了一项前瞻性、随机、对照研究，以评估相对于匹配对照组的标准护理治疗，瑜伽生活方式干预是否可以改善 HIV 感染成人的 CVD 危险因素、病毒学或免疫学状态或生活质量 (QOL)。 方法：60 名具有轻度至中度 CVD 风险的 HIV 感染成年人被分配接受为期 20 周的监督瑜伽练习或标准护理治疗。基线和第 20 周的测量包括：2 小时口服葡萄糖耐量测试，并监测胰岛素、身体成分、空腹血清脂质/脂蛋白谱、静息血压、CD4 T 细胞计数和血浆 HIV RNA，以及医疗结果研究简表（ SF)-36 与健康相关的 QOL 清单。