Core B: Human Stem Cell Core

核心B：人类干细胞核心

• 批准号: 8698736
• 负责人: Mitchell J Weiss
• 金额: $ 41.1万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8698736
• 关键词: Adherence; Adult; Benign; Bone Marrow; Bone Marrow Aspiration; Bone Marrow Cells; CD34 gene; Cell Therapy; Cell physiology; Cells; Collaborations; Collection; Commit; Conflict (Psychology); Core Facility; Cost Control; Cryopreserved Cell; Defect; Development; Discipline of obstetrics; Dysmyelopoietic Syndromes; Embryo; Ensure; Funding; Future; Growth; Guidelines; Hematologist; Hematopoiesis; Hematopoietic; Hematopoietic stem cells; Human; Individual; Institutional Review Boards; Laboratories; Leadership; Logistics; N.I.H. Research Support; Neonatal; Pancytopenia; Patients; Pennsylvania; Peripheral; Population; Price; Process; Productivity; Protocols documentation; Quality Control; Reagent; Research; Research Personnel; Resources; Running; Services; Source; Stem cells; Syndrome; Tissues; Umbilical Cord Blood; Umbilical cord structure; University Hospitals; cost effective; embryonic stem cell; experience; human stem cells; induced pluripotent stem cell; interest; new growth; progenitor; programs; ranpirnase; stem; stem cell biology

Two pre-existing functional Core Facilities will be merged under this proposal and focused on supporting the UPENN/CHOP program in benign hematopoiesis. This combined service will be entitled the Human Stem Cell Core B and will be directed by Dr. Mitchell Weiss. The two SubCores are 1) SubCore B-1, the Hematopoietic Stem Cell (HSC) Facility at UPENN, directed by Martin Carroll, and 2) SubCore B-2, the Human Embryonic Stem (ES) and Induced Pluripotent Stem (iPS) Cell Facility, which is physically present at CHOP, and will be directed by Dr. Deborah French.

该提案将合并两个预先存在的功能核心设施，并致力于支持良性造血的UPENN/CHOP计划。这项合并的服务将标题为人类干细胞核B，并由Mitchell Weiss博士指导。这两个子核为1）亚核B-1，由马丁·卡罗尔（Martin Carroll）执导的UPENN的造血干细胞（HSC）设施，以及2）亚核B-2，人类胚胎词干（ES）和诱导的多能干（IPS）细胞设施，在Chop上是Chop，并将由Deborah Franch博士指导。