Robotic Interventions to Enhance Locomotor Stability Following Spinal Cord Injury

机器人干预增强脊髓损伤后的运动稳定性

• 批准号: 8840079
• 负责人: Keith Edward Gordon
• 金额: --
• 依托单位: EDWARD HINES JR VA HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8840079
• 关键词: Address; Affect; Area; Balance training; Body Weight; Chicago; Chronic; Clinical; Computer software; Country; Development Plans; Devices; Elements; Environment; Equilibrium; Equipment; Funding; Gait; Goals; Grant; Hospitals; Institutes; Intervention; Knowledge; Lateral; Lead; Leadership; Libraries; Locomotor training; Manuscripts; Measures; Medial; Mentors; Motor; Movement; Outcome; Participant; Patients; Pelvis; Positioning Attribute; Quality of life; Reading; Rehabilitation therapy; Research; Research Project Grants; Resources; Robotics; Sensory Motor Performances; Services; Shadowing (Histology); Speed; Spinal cord injury; System; Technology; Testing; Time; Training; Travel; Veterans; Walking; Work; Writing; career development; clinical care; cost; experience; improved; improved mobility; neurophysiology; novel; programs; research and development; robotic device; software development; tool; treadmill training

DESCRIPTION (provided by applicant) Project Overview: The major goals of this proposal are to develop and test a robotic device capable of providing targeted locomotor balance training for veterans with spinal cord injury (SCI). The working hypothesis is that this novel robotic tool will transform traditional body weight supported treadmill training (BWSTT) into a dynamic environment where balance-specific components of walking are measured and adaptively challenged, thereby enhancing locomotor training outcomes. Candidate: Dr. Gordon's objective is to establish a novel and productive, independent line of research within the VA system that will benefit the quality of life of veterans affected by SCI. Dr. Gordon has significant research experience in gait rehabilitation of SCI. He has observed that effective locomotor balance training and assessment tools are lacking within this field. For the purposed project, Dr. Gordon will develop a new robotic device capable of addressing this need. Combining Dr. Gordon's past experience with the training purposed in the current project will position Dr. Gordon at the forefront of this under-explored area of SCI gait rehabilitation. Research Development Plan: Dr. Gordon has assembled a diverse mentoring team, lead by Dr. Zev Rymer, to provide training and guidance in four critical project areas; rehabilitation robotics, neurophysiology of movement following SCI, locomotor balance and clinical care of SCI. Dr. Gordon will advance his formal knowledge of these areas through a combination of course work, directed readings and clinical shadowing. Dr. Gordon will also receive career development guidance in terms of establishing, funding and growing a productive independent research program through regular group mentoring sessions, active manuscript/grant writing and participation in grant writing and leadership seminars. Environment: The proposed research project will be conducted in VA designated space within the Sensory Motor Performance Program at the Rehabilitation Institute of Chicago (RIC), the top ranked rehabilitation hospital in the country. The resources provided by RIC include dedicated research space and equipment, clinical examination areas, offices space and machine shop. Clinical training and the primary recruitment of veterans with SCI will be performed through the Spinal Cord Injury Service at Edward Hines Jr. VA Hospital. Proposed Research: Aim 1) To create a library of robotic environments capable of providing challenging, balance-specific locomotor training. Applicant proposes to develop an intelligent robotic rehabilitation tool capable of A) applying a range of dynamic balance environments, including stabilizing and/or destabilizing lateral forces applied to the pelvis during gait, B) measuring locomotor stability in real-time and C) automatically adjusting the difficulty of the balance environments to optimally challenge the abilities of the participant. The device will consist of a moving coil forcer (linear motor) rigidly attached to the posterior of a pelvic harness. Software will control travel of the coil forcer along a track aligned perpendicular to the treadmill. Thus, movement of the coil forcer will exert a medial-lateral force on the user. He will develop software to create several balance-specific training environments that can be safely and easily delivered to people with SCI during treadmill walking. Aim 2) To test the effects of targeted locomotor balance training on gait stability, walking speed and energetic efficiency in incomplete SCI subjects. He will compare the effects of BWSTT performed in one of three balance-specific training environments. Ambulatory incomplete SCI subjects will receive BWSTT with either 1) a demanding dynamic balance environment that automatically and progressively adapts to continuously challenge the subject during gait; 2) no balance assistance (similar to unassisted walking on a treadmill); or 3) fixed balance assistance (similar to current approaches to BWSTT). He hypothesizes that the dynamic balance environment will result in the greatest improvements in walking speed, energetic gait efficiency and the ability to respond to gait perturbations.

描述（由申请人提供） 项目概述：该提案的主要目标是开发和测试能够为患有脊髓损伤的退伍军人（SCI）提供针对性的运动平衡训练的机器人设备。 工作假设是，这种新型的机器人工具将将传统的体重支持的跑步机训练（BWSTT）转变为动态环境，在该环境中，测量和适应性地挑战了平衡特定的步行组成部分，从而增强了运动训练的成果。 候选人：戈登博士的目标是在VA系统中建立一种新颖而富有成效的独立研究线，这将使受SCI影响的退伍军人的生活质量有益。 戈登博士在SCI的步态康复方面具有重要的研究经验。 他已经观察到该领域缺乏有效的运动平衡训练和评估工具。 对于有目的的项目，戈登博士将开发一种能够满足这一需求的新机器人设备。 将戈登博士的过去经验与目前在当前项目中的培训相结合，将把戈登博士定位在这一不足探索的科幻步态康复领域的最前沿。 研究开发计划：戈登博士召集了由Zev Rymer博士领导的多元化指导团队，以在四个关键的项目领域提供培训和指导；康复机器人技术，SCI后运动的神经生理学，运动平衡和SCI的临床护理。 戈登博士将通过课程工作，定向阅读和临床阴影的结合来提高他对这些领域的正式知识。 戈登博士还将通过常规的小组指导会议，主动手稿/赠款写作和参与赠款写作和领导力研讨会来建立，资助和发展一项富有成效的独立研究计划，以获得职业发展指导。 环境：拟议的研究项目将在芝加哥康复研究所（RIC）的弗吉尼亚州指定空间中进行，该计划是该国排名最高的康复医院。 RIC提供的资源包括专门的研究空间和设备，临床检查区，办公室空间和机械车间。 SCI的临床培训和资深退伍军人的主要招募将通过Edward Hines Jr. VA医院的脊髓损伤服务进行。 拟议的研究：目标1）创建一个能够提供具有挑战性的特定于平衡运动训练的机器人环境库。 申请人建议开发能够a）应用一系列动态平衡环境的智能机器人康复工具，包括在步态过程中稳定和/或破坏骨盆施加到骨盆施加的横向力平衡环境难以最佳地挑战参与者的能力。 该设备将包括一个移动的线圈式（线性电动机），该固定固定在骨盆束的后部。 软件将控制线圈式沿沿着跑步机的轨道对齐的轨道的行程。 因此，线圈前的移动将对用户施加内侧力。 他将开发软件，以创建几种特定平衡的培训环境，可以在跑步机步行期间安全，轻松地将其交付给患有SCI的人。目标2）测试目标运动平衡训练对不完整SCI受试者步态稳定性，步行速度和能量效率的影响。 他将比较在特定于三个平衡的培训环境之一中执行的BWSTT的效果。 卧床不完整的SCI受试者将获得BWSTT，其中1）苛刻的动态平衡环境会自动，逐步适应步态期间不断挑战受试者； 2）没有平衡援助（类似于在跑步机上无助行走）；或3）固定平衡援助（类似于当前的BWSTT方法）。 他假设动态平衡环境将导致步行速度，高能步态效率以及对步态扰动做出反应的能力的最大改善。