Intergrative Health Sciences Core

综合健康科学核心

基本信息

批准号：
8650855
负责人：
Joel Daniel Kaufman
金额：
$ 37.71万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-04-01 至 2016-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8650855
关键词：
Analytical Biochemistry Animals Area Basic Science Bioinformatics Biological Markers Biometry Biostatistics Core Chronic Disease Clinical Clinical Research Collaborations Consultations Core Facility Cytology Data Discipline Ensure Environmental Health Environmental Risk Factor Epidemiology Epigenetic Process Fostering Genetic Goals Health Policy Health Sciences Histology Human Image Immunohistochemistry Interdisciplinary Study Mass Spectrum Analysis Metabolic Mission Molecular Phenotype Proteomics Public Health Recording of previous events Research Research Design Research Personnel Resources Services Systems Biology Technology Transgenic Animals Translational Research Universities Washington bench to bedside cost functional genomics health practice innovation metabolomics population based research clinical testing small molecule virtual

项目摘要

The Integrative Environmental Health Sciences Facility Core (lEHSFC) serves the CEEH as a focal point for interdisciplinary research, the portal for accessing Center services, and a comprehensive consultation resource to assist CEEH investigators and trainees, emphasizing clinical, translational, and population-based studies. The lEHSFC allows UW EHS research to move as smoothly as possible not only from "bench-to-bedside" but also from population-based observations to bench to clinical research and onward to public health policy and practice. This facility core builds on a rich history of environmental health translational and epidemiological research at the UW. The lEHSFC facilitates EHS research¿including translational research~and fosters the integration of basic sciences research at the University of Washington with population-based and clinical EHS research. The core's mission is to provide access and consultation to CEEH investigators to ensure that the most modern molecular and 'systems biology' approaches are used to identify the interactions between genetic, epigenetic and environmental factors that contribute to the major chronic diseases. The core is comprised of three units: the Clinical/Translational Services Unit (CTSU), the Bioinformatics and Biostatistics Unit (BBU, this unit also includes OMICs integration), and the Technology Access Unit (TAU). The Bioinformatics and Biostatistics Unit provides many of the services that were previously provided by a dedicated Bioinformatics and Biostatistics Core. The other two units provide suites of services that are essentially new in this proposal. While the core offers a myriad of concrete services (and even a dedicated space for clinical evaluation in the CTSU), the core is first and foremost a literal and virtual collaborative space dedicated to encouraging and enabling innovative translational research and collaborations across disciplines at the UW.

综合环境健康科学核心核心（LEHSFC）将CEEH作为跨学科CCESING CENTE CENTER服务的焦点，以及全面的CEEH研究人员和受训者，基于翻译的人群研究。 LEHSFC不仅要尽可能顺利地进行所有行动。从人口低下的观察台上到临床研究，再到公共卫生政策和实践。这种设施核心基于环境健康转化和流行病学的丰富历史 UW的研究。包括翻译研究〜并促进了华盛顿大学基础科学研究与临床EHS研究的整合。遗传，表观遗传学和环境因素有助于主导。核心由三个单元（CTSU）组成，还包括OMICS集成），并且技术访问单元（TAU）。核心提供了混凝土服务（以及在COTSU中进行临床评估的事件的空间），核心首先是一个字面和虚拟的协作空间，致力于鼓励和实现跨学科的创新转化搜索和协作在UW。