University of Iowa Institute for Clinical and Translational Science

爱荷华大学临床与转化科学研究所

基本信息

批准号：
8604041
负责人：
GARY E ROSENTHAL
金额：
$ 408.66万
依托单位：
UNIVERSITY OF IOWA
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-09-01 至 2015-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8604041
关键词：
Academic Medical Centers Adoption Applications Grants Arts Awareness Back Biotechnology Businesses Cardiovascular Diseases Caring Child Child health care Chronic Disease Clinic Clinical Clinical Research Clinical Sciences Collaborations Communities Contracts County Data Data Collection Dentistry Dentists Discipline of Nursing Education Elderly Enabling Factors Engineering Environment Epidemiologic Studies Estrogens Face Faculty Fostering Funding Goals Grant Health Alliance Health Personnel Healthcare Heart Hospitals Individual Informatics Institutes Institution Institutional Review Boards Iowa Knowledge Laboratories Laws Link Longitudinal Studies Medical center Medicine Mental disorders Modeling National Institute of Child Health and Human Development Nurses Patients Perinatal Pharmacists Pharmacy facility Physicians Population Positioning Attribute Postmenopause Primary Health Care Procedures Program Evaluation Protocols documentation Provider Public Health Dentistry Recruitment Activity Research Research Infrastructure Research Institute Research Personnel Research Support Research Training Resource Allocation Resources Risk Factors Role Rural Rural Community Rural Population Science Scientist Secure Services Shapes Site Stable Populations System Teaching Hospitals Testing Time Training Programs Training Support Translational Research Trust Underserved Population United States National Institutes of Health Universities Woman Women&apos s Health Work base bench to bedside career clinical practice college cost drug development drug discovery health care delivery improved innovation interdisciplinary collaboration loss of function medical specialties member novel novel strategies population based programs public health relevance science education success translational study

项目摘要

DESCRIPTION (provided by applicant): The University of Iowa (Ul) Institute for Clinical and Translational Science (ICTS) is ideally positioned to accomplish the ultimate goal of the CTSA initiative - to promote the true translation of research from bench to bedside, to community, to individual patient, and back. Since its creation, the ICTS has successfully engaged investigators, trainees, and research staff from all 11 Ul colleges -- Medicine, Public Health, Dentistry, Nursing, Pharmacy, Engineering, Liberal Arts and Sciences, Education, Law, Business, and Graduate. The ICTS also crafted collaborations with Iowa State University, the VA Midwest Health Care Network, the Iowa Primary Care Association, and clinical networks that care for rural and other underserved populations and that support T2 - T4 translational studies. This application will further enhance our infrastructures, facilitate more sophisticated translational research, position the ICTS to assume an even greater institutional role in improving regulatory procedures, and increase access of our collaborating organizations to clinical research support and data warehousing and access of other CTSA institutions to our unique resources. The four aims related to these efforts are to: 1) Catalyze innovative T1 - T4 Science through: new pilot programs to support interdisciplinary high impact research; facilitation of new collaborations between bench, clinical, and population-based scientists; enhancement of the environment for team science; and a new program in drug discovery and development. 2) Improve research efficiency through: novel approaches to increase subject recruitment and decrease data collection costs; adoption of shared IRB arrangements and master contracts; supporting NIH multi-site research networks; and tightly linking program evaluation data to decisions about resource allocation. 3) Create and nurture partnerships with: Ul research centers to leverage resources and avoid duplication of services; regional healthcare providers to expand opportunities for T2 - T4 research; other CTSA institutions to disseminate novel Ul products and import promising scientific and administrative approaches; and private biotechnology firms. 4) Build dynamic educational, service, and informatics infrastructures to: support the training needs of translational investigators across the career spectrum; support the research services needs of T1 - T4 investigators; and enable highly productive, safe and secure research.

描述（由申请人提供）：爱荷华大学（UL）临床和转化科学研究所（ICT）的理想位置可以实现CTSA倡议的最终目标 - 促进研究从长凳到床边，向社区，再到个人患者和背部的真正翻译。自创建以来，ICT已成功地吸引了来自所有11所UL学院的研究人员，学员和研究人员 - 医学，公共卫生，牙科，护理，药学，工程，工程，文科和科学，教育，法律，商业，商业和毕业生。 ICT还与爱荷华州立大学，VA中西部卫生保健网络，爱荷华州初级保健协会以及照顾农村和其他服务不足的人群的临床网络共同制定了合作，并支持T2 -T4转化研究。该应用程序将进一步增强我们的基础架构，促进更复杂的翻译研究，使ICT在改善监管程序中扮演更大的机构作用，并增加我们的合作组织对临床研究支持和数据仓库的访问，并访问其他CTSA机构，以便其他CTSA机构访问我们独特的独特资源。与这些努力相关的四个目标是：1）通过：支持跨学科高影响研究的新试点计划来催化创新的T1 -T4科学；促进替补席，临床和基于人群的科学家之间的新合作；增强团队科学环境；以及一项新的药物发现和开发计划。 2）通过以下方式提高研究效率：增加受试者招聘并降低数据收集成本的新方法；采用共享的IRB安排和总合同；支持NIH多站点研究网络；并将程序评估数据紧密地链接到有关资源分配的决策。 3）与：UL研究中心建立和培育合作伙伴关系，以利用资源并避免重复服务；区域医疗保健提供者扩大T2 -T4研究的机会；其他CTSA机构传播新型UL产品并进口有希望的科学和行政方法；和私人生物技术公司。 4）建立动态的教育，服务和信息学基础设施以：支持整个职业范围内翻译调查员的培训需求；支持T1 -T4研究人员的研究服务需求；并启用高产，安全和安全的研究。