Mentoring in advanced mHealth interventions for drug abuse and HAART adherence

指导针对药物滥用和 HAART 依从性的先进移动医疗干预措施

基本信息

批准号：
8789850
负责人：
Edward W Boyer
金额：
$ 17.53万
依托单位：
UNIV OF MASSACHUSETTS MED SCH WORCESTER
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-07-01 至 2019-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8789850
关键词：
Abstinence Adherence Adult Advanced Development Affect Affective Anti-Retroviral Agents Area Award Behavior Therapy Behavioral Behavioral Sciences Biosensing Techniques Biosensor Boredom Car Phone Cellular Phone Chronic Clinical Research Clinical Trials Cognitive Collaborations Communication Computers Deterioration Development Discipline Drug abuse Drug usage Effectiveness Electrical Engineering Elements Employee Strikes Engineering Ensure Environment Fatigue Feeds Friends Funding General Population Goals Grant HIV Health Health Promotion Health Technology Healthcare Highly Active Antiretroviral Therapy Human Individual Interdisciplinary Study Internet Interruption Intervention Investigation Knowledge Learning Length Life Location Massachusetts Medical Mentors Methods Minority Mission Multimedia National Institute of Drug Abuse Nature Patient Care Patients Pattern Recognition Penetrance Persons Pharmaceutical Preparations Population Publishing Relapse Research Research Methodology Research Personnel Rest Risk Behaviors Scientist Source Technology Text Time Training Training Support Translational Research United States United States National Institutes of Health Universities Wireless Technology Work base behavioral health career clinical application design design and construction digital experience handheld mobile device improved innovation interest mHealth medical schools medication compliance novel novel strategies patient oriented patient oriented research prevent programs public health relevance ranpirnase skills socioeconomics substance abuse treatment theories therapy design tool treatment effect usability

项目摘要

DESCRIPTION (provided by applicant): This K24 proposal builds on my strong record of successful mentoring and original investigation to generate research capacity in the area of mobile technologies to improve health (mHealth). I have mentored 21 clinician-scientists, 15 of whom have been awarded NIH funding under K23, K08, R01, R21, R03, Loan Repayment Program, and Minority Supplement mechanisms. Of the 16 clinician-scientists whom I currently mentor, 12 have engaged in mHealth-related research. My responsibilities in the University of Massachusetts (UMass) CTSA-funded mentoring programs, my collaborations with the NIDA-funded P30 Center for Technology and Behavioral Health at Dartmouth Medical School, referrals from NIDA program staff, and other efforts have expanded the scope of my mentoring and ensured a nationwide source of mentees. My patient-oriented research focuses on mHealth approaches to substance abuse treatment and improving medication adherence in persons with HIV. The striking increase in the use of mobile technologies has created great opportunities for delivery of health interventions in natural environments at the time and location they are needed most. Despite the broad reach, multimedia capabilities, and computing power of mobile technologies, several features threaten the acceptability of smartphone-delivered behavioral interventions and detract from their enormous potential as effective health promotion tools. The ultimate goal of this proposal, therefore, is to create mobile technology-driven interventions capable of producing persistent beneficial health effects. The overall research goal of the K24 is to develop new classes of mHealth behavioral interventions through three synergistic research thrusts. The first involves the development of advanced mHealth behavioral interventions that support long-term abstinence, prevent relapse, and promote antiretroviral adherence in HIV+ patients. The second involves development of mobile biosensing methods that can assess the effectiveness of these highly innovative interventions by identifying the onset and duration of drug use episodes. In a third line of investigation, I intend to elucidate the design elements that will maximize the usability and acceptability of novel mHealth behavioral interventions. The overall mentoring objective of this K24 is to develop researchers who not only have the skills to develop, implement, and publish hypothesis driven, patient-oriented mHealth research, but who understand the importance of bringing a multi-method, multi-disciplinary approach to clinical and translational research problems. My mentoring approach emphasizes the importance of tailoring research methods to the nature of the problem of interest, even if that means learning new behavioral science, engineering, and clinical research methods or developing collaborations with investigators from other disciplines familiar with those methods. The proposed research is relevant to the NIH's mission because the lessons learned from this drug abuse- and HIV-related work are directly applicable to the care of patients with other common, intractable, and expensive conditions amenable to behavioral interventions.

描述（由申请人提供）：该K24提案建立在我成功的指导和原始调查记录的基础上，以在移动技术领域产生改善健康的研究能力（MHealth）。我指导了21名临床医生，其中15名获得了K23，K08，R01，R21，R03，贷款还款计划和少数族裔补充机制的资助。在我目前指导的16位临床医生中，有12名参与了与MHealth相关的研究。我在马萨诸塞大学（UMass）CTSA资助的指导计划中的职责，我与Dartmouth医学院的NIDA资助的P30资助的P30 P30技术和行为健康中心的合作，NIDA计划人员的推荐，其他努力扩大了我的指导范围，并确保了全国范围的导师。我以患者为导向的研究重点介绍了MHealth的滥用药物治疗方法，并改善了艾滋病毒患者的药物依从性。移动技术使用的惊人增加为在最需要的时间和位置提供了自然环境中提供健康干预措施的绝佳机会。尽管有广泛的范围，多媒体功能以及移动技术的计算能力，但一些功能仍威胁着智能手机传递的行为干预措施的可接受性，并削弱了它们作为有效的健康促进工具的巨大潜力。因此，该提案的最终目标是创建能够产生持续的有益健康影响的移动技术驱动的干预措施。 K24的总体研究目标是通过三个协同研究推力开发新的MHealth行为干预措施。首先涉及发展高级MHealth行为干预措施，这些干预措施支持长期禁欲，防止复发并促进HIV+患者的抗逆转录病毒依从性。第二个涉及开发移动生物传感方法，这些方法可以通过确定吸毒发作的发作和持续时间来评估这些高度创新的干预措施的有效性。在第三次调查中，我打算阐明设计元素将最大化新型MHealth行为干预的可用性和可接受性。该K24的总体指导目标是发展研究人员，这些研究人员不仅具有开发，实施和发布假设驱动的，以患者为导向的MHealth研究的技能，而且还了解将多学科，多学科方法引入临床和翻译研究问题的重要性。我的指导方法强调了量身定制研究方法对感兴趣问题的性质的重要性，即使这意味着学习新的行为科学，工程和临床研究方法或与来自其他熟悉这些方法的其他学科的研究人员进行合作。拟议的研究与NIH的使命有关，因为从这项与毒品滥用和HIV相关的工作中学到的经验教训直接适用于其他常见，棘手且昂贵的疾病的患者的护理，可用于行为干预措施。