Developmental Research Program

发展研究计划

基本信息

批准号：
8805241
负责人：
FRANCIS ALI-OSMAN
金额：
$ 9.01万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-09-24 至 2019-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8805241
关键词：
Advertisements African American Area Attention Award Basic Science Bioinformatics Biological Brain Brain Neoplasms Cancer Center Clinical Clinical Research Clinical Sciences Clinical and Translational Science Awards Collaborations Communities Data Development Diagnosis Ensure Evaluation Evolution Faculty Feedback Fostering Funding Funding Mechanisms Goals Grant Individual Industry Institutes Institution Journals Laboratories Leadership Malignant Neoplasms Malignant neoplasm of brain Measurement Medical Medicine Minority North Carolina Patients Peer Review Prevention Probability Process Progress Reports Recruitment Activity Research Research Infrastructure Research Personnel Research Project Grants Resources Scientist Source Testing Translating Translational Research United States National Institutes of Health Universities Update Woman Work Writing base bench to bedside experience improved innovation interest medical schools meetings member neuro-oncology novel novel strategies professor programs translational medicine

项目摘要

The Developmental Research Program (DRP) is a critical component of the Duke SPORE in Brain Cancer. The goal of the Program is to identify and support promising pilot research projects with translational research potential relevant to brain tumors from experienced investigators in other fields. Projects will be encouraged to be broadly collaborative and to test novel paradigms that will further expand the scope of brain tumor diagnosis, prevention, and management. The DRP will specifically target projects that have a strong likelihood of becoming successful and independent research projects or have a high potential of developing into full SPORE projects to replace projects within the SPORE that are not progressing satisfactorily. The Specific Aims of the DRP are to: 1) Identify and support meritorious translational research projects from experienced investigators in other fields that have a high probability of impacting the diagnosis, treatment or prevention of brain tumors; 2) Attract new, outstanding, and experienced investigators currently not working on brain tumors to pursue brain tumor research; and 3) Provide continuing evaluation of progress on funded projects and facilitate their evolution into full SPORE projects or independently funded projects. The proposed Duke SPORE in Brain Cancer DRP builds upon the highly successful DRP of the previous Duke Brain SPORE that had resulted in several peer-reviewed funded projects. In this new application, we present a strong plan for project identification, selection, and evaluation that will ensure that we support exciting new projects, as evidenced by the examples of potential projects listed in the application. We also expect to attract outstanding new individuals to work in the brain tumor field and to facilitate new productive collaborations between Duke brain tumor investigators and investigators in other components of Duke University, other institutions, and industry. We have also put in place a comprehensive plan, including interactions with the Duke School of Medicine Office of Diversity and the Duke Office of Biomedical Graduate Diversity, as well as, partnerships with select local institutions, such as the predominantly black North Carolina Central University, to increase the participation, in the DRP, of outstanding minority and women investigators with research interests relevant to brain tumors.

发展研究计划 (DRP) 是杜克大脑 SPORE 的重要组成部分癌症。该计划的目标是确定并支持具有转化能力的有前途的试点研究项目来自其他领域经验丰富的研究人员与脑肿瘤相关的研究潜力。项目将是鼓励广泛合作并测试将进一步扩大大脑范围的新范式肿瘤的诊断、预防和治疗。 DRP 将专门针对具有强大实力的项目成为成功的独立研究项目的可能性或具有很高的发展潜力纳入完整的 SPORE 项目，以取代 SPORE 内进展不理想的项目。这 DRP 的具体目标是： 1) 识别并支持经验丰富的研究人员的优秀转化研究项目其他很可能影响诊断、治疗或预防的领域脑肿瘤； 2）吸引目前不从事脑肿瘤研究的新的、优秀的、经验丰富的研究人员从事脑肿瘤研究；和 3) 对资助项目的进展进行持续评估，并促进其发展为完整的 SPORE 项目或独立资助的项目。拟议的脑癌 DRP 中的 Duke SPORE 建立在前任 Duke 非常成功的 DRP 的基础上 Brain SPORE 已经产生了几个经过同行评审的资助项目。在这个新应用程序中，我们提出了一个强有力的项目识别、选择和评估计划将确保我们支持令人兴奋的新项目项目，如申请中列出的潜在项目示例所示。我们还期望吸引杰出新人在脑肿瘤领域工作并促进新的富有成效的合作杜克脑肿瘤研究人员和杜克大学其他部门的研究人员之间的研究机构和行业。我们还制定了一项全面的计划，包括与公爵的互动医学院多样性办公室和杜克大学生物医学研究生多样性办公室，以及，与特定的当地机构（例如以黑人为主的北卡罗来纳中央大学）建立伙伴关系，增加具有研究兴趣的杰出少数族裔和女性调查员对 DRP 的参与与脑肿瘤有关。