2014 Mammalian Reproduction Gordon Research Conference

2014年哺乳动物繁殖戈登研究会议

• 批准号: 8776096
• 负责人: John R MCCARREY
• 金额: $ 1.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-06 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8776096
• 关键词: Address; Affect; Area; Basic Science; Biology; Canada; Clinical; Collaborations; Communication; Contraceptive methods; Couples; Developed Countries; Development; Disabled Persons; Embryo; Epigenetic Process; Faculty; Family Planning; Female; Fostering; Genomics; Germ Cells; Goals; Gonadal structure; Health; Healthcare Systems; Infertility; Knowledge; Learning; Male Contraceptions; Malignant neoplasm of cervix uteri; Malignant neoplasm of prostate; Malignant neoplasm of testis; Medicine; Methods; North America; Ovarian; Ovary; Polycystic Ovary Syndrome; Population; Population Control; Postdoctoral Fellow; Pregnancy; Reproduction; Reproductive Biology; Reproductive Medicine; Reproductive system; Research; Scientist; Solutions; Stem cells; System; Testis; Time; Tissues; Translating; Translational Research; Underrepresented Minority; United States; Uterine Cancer; Woman; bench to bedside; career development; case-based; clinically relevant; design; endometriosis; female reproductive system; graduate student; interest; male; member; novel; planetary Atmosphere; professor; programs; public health relevance; reproductive; reproductive development; reproductive function; reproductive system disorder; symposium

DESCRIPTION (provided by applicant): Infertility is a problem that affects approximately 12-15% of couples in developed countries including the United States and Canada, and a significant portion of these cases are based on unknown causes (idiopathic infertility). At the same time, the need and desire for population control and family planning remain at an all-time high throughout the world and represent priorities in the US and Canada. In addition, diseases of the reproductive systems (e.g., ovarian, cervical, uterine, testicular or prostate cancer, endometriosis, polycystic ovary syndrome, and many others) impose a large burden on the US healthcare system. Taken together, these considerations impact a large proportion of the population in North America and therefore translate into very significant financial, political and cultural priorities in this region. Enhanced knowledge of the reproductive systems in general, and specific aspects of these systems including the gonads (testes and ovaries), the germ cells (spermatogenic and oogenic), the male and female reproductive tracts, and early embryos, represent the most promising avenue to the discovery of breakthroughs that will yield novel solutions to infertility or reproductive system diseases, or toward the development of novel methods of contraception. The new Gordon Research Conference on Mammalian Reproduction is designed to bring together experts in basic and translational research in multiple areas of reproductive biology and reproductive medicine. Topics to be discussed will include fate determination and development of reproductive tissues, epigenetic programming and reproduction, stem cells and reproduction, environmental effects on reproductive functions, pregnancy and par tuition, infertility and contraception, male reproductive tract, genomics and systems approaches to reproduction, and the founders' forum featuring scientists who have made lasting contributions to the field of reproductive biology/medicine.

描述（由申请人提供）：在美国和加拿大等发达国家，不孕不育症影响着大约 12-15% 的夫妇，其中很大一部分病例是由于不明原因（特发性不孕症）造成的。与此同时，世界各地对人口控制和计划生育的需求和愿望仍然处于历史最高水平，并且是美国和加拿大的优先事项。此外，生殖系统疾病（例如卵巢癌、宫颈癌、子宫癌、睾丸癌或前列腺癌、子宫内膜异位症、多囊卵巢综合征等）给美国医疗保健系统带来巨大负担。总而言之，这些考虑因素影响着北美很大一部分人口，因此转化为该地区非常重要的金融、政治和文化优先事项。增强对生殖系统的一般知识，以及这些系统的具体方面，包括性腺（睾丸和卵巢）、生殖细胞（生精细胞和卵细胞）、男性和女性生殖道以及早期胚胎，代表了最有希望的途径发现的突破将为不孕症或生殖系统疾病提供新的解决方案，或开发新的避孕方法。新的戈登哺乳动物生殖研究会议旨在汇集生殖生物学和生殖医学多个领域的基础和转化研究专家。讨论的主题将包括生殖组织的命运决定和发育、表观遗传编程和生殖、干细胞和生殖、环境对生殖功能的影响、怀孕和生育、不孕和避孕、男性生殖道、生殖基因组学和系统方法、创始人论坛由对生殖生物学/医学领域做出持久贡献的科学家组成。