Chicago D-CFAR

芝加哥 D-CFAR

• 批准号: 8820373
• 负责人: Alan L Landay
• 金额: $ 34.42万
• 依托单位: RUSH UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8820373
• 关键词: AIDS clinical trial group; AIDS/HIV problem; Academic Medical Centers; Acquired Immunodeficiency Syndrome; Address; Adolescent; Adult; Affect; Age; Aging; Area; Basic Science; Behavioral; Behavioral Research; Behavioral Sciences; Biomedical Research; Caring; Chicago; Childhood; Cities; Clinical; Clinical Research; Clinical Sciences; Collaborations; Commit; Communicable Diseases; Communication; Communities; Complement; Complex; County; Databases; Detection; Development; Discipline; Discipline of Nursing; Drug abuse; Education; Educational Materials; Educational workshop; Electronic Mail; Electronics; Eligibility Determination; Endocrinologist; Enrollment; Environment; Epidemiologic Studies; Epidemiology; Event; Faculty; Fostering; Funding; Funding Opportunities; Future; Generations; Goals; Grant; HIV; HIV Infections; HIV vaccine; Health Sciences; Health Services; High Prevalence; Illinois; Immunology; Indigent; Individual; Infection; Institution; Interdisciplinary Study; International; Investigation; Laboratories; Laboratory Study; Lead; Leadership; Learning; Link; Location; Medical; Medicine; Mentors; Metabolic; Microbiology; Minority; Monitor; Neighborhoods; Participant; Pathogenesis; Patients; Physicians; Pilot Projects; Population; Prevalence; Prevention; Primary Health Care; Process; Productivity; Public Health; Public Health Schools; Relative (related person); Research; Research Activity; Research Infrastructure; Research Personnel; Research Priority; Research Project Grants; Research Support; Resources; Retrovirology; Schedule; Schools; Science; Scientist; Site; Source; Specimen; System; Techniques; Time; Transcend; Translational Research; United States; United States National Institutes of Health; Universities; Update; Woman; Women' s Health; Work; base; behavioral/social science; career; cohort; college; computerized; cooking; design; improved; inner city; innovation; interdisciplinary collaboration; interest; meetings; member; men; multidisciplinary; news; novel; prevent; programs; quality assurance; repository; sex; social; symposium; therapeutic vaccine; user-friendly; virology; web site

DESCRIPTION (provided by applicant): Chicago has the 6th highest HIV prevalence of large cities in the US; three medical institutions are located right in the middle of the communities with the highest prevalence of HIV in Chicago. More than 100 investigators in these institutions are currently involved in HIV/AIDS research. This proposal is to establish a Chicago Developmental Center for AIDS Research (D-CFAR) that will include Rush University Medical Center (RUMC), the University of Illinois at Chicago (UIC), and the Cook County Bureau of Health Services (Cook County) and will foster HIV/AIDS related research productivity. Dr. Alan Landay (RUMC) will be the Director and Dr. Robert Bailey (UIC) will be the Co-Director. The D-CFAR will build upon existing collaborative research efforts in basic, clinical, and behavioral science and will work toward expanding research opportunities for junior HIV investigators and to engage senior investigators from other disciplines in HIV/AIDS research. We plan to 1) develop an infrastructure that enhances HIV research across institutional boundaries, 2) work toward establishing interdisciplinary collaborations between investigators in the basic, social and behavioral and clinical areas of research, 3) encourage innovative research in HIV/AIDS, 4) improve communication between Chicago D-CFAR participants by creating a web site (www.ChicagoDCFAR. org), distributing a database of participants and emailing news of D-CFAR events to all participants, 5) develop access to HIV educational material, 6) develop a communication strategy for bringing advances in HIV/AIDS research to the community and 7) build an infrastructure to enable us to move from a D-CFAR to a CFAR. We will accomplish these goals by creating Cores and Emphasis Areas. There will be: an Administrative Core (Drs. Alan Landay and Linda Baum); a Developmental Core (Drs. Greg Spear and Ron Hershow); a Basic Science Core (Drs. Michael Caffrey and James Bremer); a Clinical Core (Drs. Audrey French and Richard Novak); and a Social and Behavioral Sciences Core (Drs. Judith Levy and Robert Bailey). We will actively promote research in: HIV and Women (Ms. Kathleen Weber); HIV and Aging (Dr. Pauline Maki) and Drug Abuse and HIV (Dr. Celeste Napier).

描述（由申请人提供）：芝加哥在美国大城市的HIV患病率是第六；三家医疗机构位于芝加哥艾滋病毒率最高的社区中间。目前，这些机构中有100多名研究人员参与了艾滋病毒/艾滋病研究。该建议是建立芝加哥艾滋病研究中心（D-CFAR），其中包括拉什大学医学中心（RUMC），芝加哥伊利诺伊大学（UIC）和库克县卫生服务局（Cook County），并将促进艾滋病毒/艾滋病相关的研究生产力。 Alan Landay博士（RUMC）将担任董事，Robert Bailey博士（UIC）将担任联合导演。 D-CFAR将基于现有的基础，临床和行为科学的合作研究工作，并将致力于扩大初级艾滋病毒研究者的研究机会，并吸引来自艾滋病毒/艾滋病研究中其他学科的高级研究人员。 We plan to 1) develop an infrastructure that enhances HIV research across institutional boundaries, 2) work toward establishing interdisciplinary collaborations between investigators in the basic, social and behavioral and clinical areas of research, 3) encourage innovative research in HIV/AIDS, 4) improve communication between Chicago D-CFAR participants by creating a web site (www.ChicagoDCFAR. org), distributing a database of participants and将D-CFAR事件的新闻发送给所有参与者，5）建立对艾滋病毒教育材料的访问权限，6）制定了一种传播策略，以将艾滋病毒/艾滋病研究的进步带到社区，并建立一个基础架构，使我们能够从D-CFAR转移到CFAR。我们将通过创建核心和强调领域来实现这些目标。将会有：行政核心（Alan Landay博士和Linda Baum）；发展核心（格雷格·斯皮尔（Greg Spear）和罗恩（Ron Hershow）博士）；基础科学核心（迈克尔·卡夫里（Michael Caffrey）和詹姆斯·布雷默（James Bremer）博士）；临床核心（Audrey French和Richard Novak博士）；以及社会和行为科学核心（Judith Levy博士和罗伯特·贝利（Robert Bailey））。我们将积极促进：艾滋病毒和妇女（凯瑟琳·韦伯女士）的研究；艾滋病毒和衰老（Pauline Maki博士）和药物滥用和艾滋病毒（Celeste Napier博士）。

项目成果

Penile coital injuries in men decline after circumcision: Results from a prospective study of recently circumcised and uncircumcised men in western Kenya.

• DOI: 10.1371/journal.pone.0185917
• 发表时间: 2017
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Westercamp N;Mehta SD;Jaoko W;Okeyo TA;Bailey RC
• 通讯作者: Bailey RC

Effects of cryopreservation on effector cells for antibody dependent cell-mediated cytotoxicity (ADCC) and natural killer (NK) cell activity in (51)Cr-release and CD107a assays.

• DOI: 10.1016/j.jim.2014.01.017
• 发表时间: 2014-04
• 期刊: Journal of immunological methods
• 影响因子: 2.2
• 作者: Mata MM;Mahmood F;Sowell RT;Baum LL
• 通讯作者: Baum LL

Should male circumcision be advocated for genital cancer prevention?

是否应该提倡男性包皮环切术来预防生殖器癌症？

• DOI: 10.7314/apjcp.2012.13.9.4839
• 发表时间: 2012
• 期刊: Asian Pacific journal of cancer prevention : APJCP
• 作者: Morris,BrianJ;Mindel,Adrian;Tobian,AaronAr;Hankins,CatherineA;Gray,RonaldH;Bailey,RobertC;Bosch,Xavier;Wodak,AlexD
• 通讯作者: Wodak,AlexD

Voluntary medical male circumcision: an HIV prevention priority for PEPFAR.

• DOI: 10.1097/qai.0b013e31825cac4e
• 发表时间: 2012-08-15
• 期刊: Journal of acquired immune deficiency syndromes (1999)
• 作者: Reed JB;Njeuhmeli E;Thomas AG;Bacon MC;Bailey R;Cherutich P;Curran K;Dickson K;Farley T;Hankins C;Hatzold K;Justman J;Mwandi Z;Nkinsi L;Ridzon R;Ryan C;Bock N
• 通讯作者: Bock N

Can we broaden the applicability of HIV transmission cluster analyses?

我们能否扩大艾滋病毒传播聚类分析的适用范围？

• DOI: 10.1097/qad.0b013e3283522d81
• 发表时间: 2012
• 期刊: AIDS (London, England)
• 作者: Lubelchek,RonaldJ;Beavis,KathleenG;Gonzalez,Marisol;Kendrick,SabrinaR;Roberts,RebeccaR;Barker,DavidE
• 通讯作者: Barker,DavidE