Chicago D-CFAR

芝加哥 D-CFAR

• 批准号: 8820373
• 负责人: Alan L Landay
• 金额: $ 34.42万
• 依托单位: RUSH UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8820373
• 关键词: AIDS clinical trial group; AIDS/HIV problem; Academic Medical Centers; Acquired Immunodeficiency Syndrome; Address; Adolescent; Adult; Affect; Age; Aging; Area; Basic Science; Behavioral; Behavioral Research; Behavioral Sciences; Biomedical Research; Caring; Chicago; Childhood; Cities; Clinical; Clinical Research; Clinical Sciences; Collaborations; Commit; Communicable Diseases; Communication; Communities; Complement; Complex; County; Databases; Detection; Development; Discipline; Discipline of Nursing; Drug abuse; Education; Educational Materials; Educational workshop; Electronic Mail; Electronics; Eligibility Determination; Endocrinologist; Enrollment; Environment; Epidemiologic Studies; Epidemiology; Event; Faculty; Fostering; Funding; Funding Opportunities; Future; Generations; Goals; Grant; HIV; HIV Infections; HIV vaccine; Health Sciences; Health Services; High Prevalence; Illinois; Immunology; Indigent; Individual; Infection; Institution; Interdisciplinary Study; International; Investigation; Laboratories; Laboratory Study; Lead; Leadership; Learning; Link; Location; Medical; Medicine; Mentors; Metabolic; Microbiology; Minority; Monitor; Neighborhoods; Participant; Pathogenesis; Patients; Physicians; Pilot Projects; Population; Prevalence; Prevention; Primary Health Care; Process; Productivity; Public Health; Public Health Schools; Relative (related person); Research; Research Activity; Research Infrastructure; Research Personnel; Research Priority; Research Project Grants; Research Support; Resources; Retrovirology; Schedule; Schools; Science; Scientist; Site; Source; Specimen; System; Techniques; Time; Transcend; Translational Research; United States; United States National Institutes of Health; Universities; Update; Woman; Women' s Health; Work; base; behavioral/social science; career; cohort; college; computerized; cooking; design; improved; inner city; innovation; interdisciplinary collaboration; interest; meetings; member; men; multidisciplinary; news; novel; prevent; programs; quality assurance; repository; sex; social; symposium; therapeutic vaccine; user-friendly; virology; web site

DESCRIPTION (provided by applicant): Chicago has the 6th highest HIV prevalence of large cities in the US; three medical institutions are located right in the middle of the communities with the highest prevalence of HIV in Chicago. More than 100 investigators in these institutions are currently involved in HIV/AIDS research. This proposal is to establish a Chicago Developmental Center for AIDS Research (D-CFAR) that will include Rush University Medical Center (RUMC), the University of Illinois at Chicago (UIC), and the Cook County Bureau of Health Services (Cook County) and will foster HIV/AIDS related research productivity. Dr. Alan Landay (RUMC) will be the Director and Dr. Robert Bailey (UIC) will be the Co-Director. The D-CFAR will build upon existing collaborative research efforts in basic, clinical, and behavioral science and will work toward expanding research opportunities for junior HIV investigators and to engage senior investigators from other disciplines in HIV/AIDS research. We plan to 1) develop an infrastructure that enhances HIV research across institutional boundaries, 2) work toward establishing interdisciplinary collaborations between investigators in the basic, social and behavioral and clinical areas of research, 3) encourage innovative research in HIV/AIDS, 4) improve communication between Chicago D-CFAR participants by creating a web site (www.ChicagoDCFAR. org), distributing a database of participants and emailing news of D-CFAR events to all participants, 5) develop access to HIV educational material, 6) develop a communication strategy for bringing advances in HIV/AIDS research to the community and 7) build an infrastructure to enable us to move from a D-CFAR to a CFAR. We will accomplish these goals by creating Cores and Emphasis Areas. There will be: an Administrative Core (Drs. Alan Landay and Linda Baum); a Developmental Core (Drs. Greg Spear and Ron Hershow); a Basic Science Core (Drs. Michael Caffrey and James Bremer); a Clinical Core (Drs. Audrey French and Richard Novak); and a Social and Behavioral Sciences Core (Drs. Judith Levy and Robert Bailey). We will actively promote research in: HIV and Women (Ms. Kathleen Weber); HIV and Aging (Dr. Pauline Maki) and Drug Abuse and HIV (Dr. Celeste Napier).

描述（由申请人提供）：芝加哥的艾滋病毒感染率在美国大城市中排名第六；三个医疗机构位于芝加哥艾滋病毒感染率最高的社区中心。这些机构目前有 100 多名研究人员参与艾滋病毒/艾滋病研究。该提案旨在建立芝加哥艾滋病研究发展中心 (D-CFAR)，其中包括拉什大学医学中心 (RUMC)、伊利诺伊大学芝加哥分校 (UIC) 和库克县卫生服务局（库克县）并将提高与艾滋病毒/艾滋病相关的研究生产力。 Alan Landay 博士（RUMC）将担任主任，Robert Bailey 博士（UIC）将担任联合主任。 D-CFAR 将建立在基础、临床和行为科学领域现有合作研究成果的基础上，致力于扩大初级艾滋病毒研究人员的研究机会，并吸引其他学科的高级研究人员参与艾滋病毒/艾滋病研究。我们计划 1) 开发一个基础设施，加强跨机构边界的艾滋病毒研究，2) 努力在基础、社会、行为和临床研究领域的研究人员之间建立跨学科合作，3) 鼓励艾滋病毒/艾滋病方面的创新研究，4)通过创建网站 (www.ChicagoDCFAR.org)、分发参与者数据库以及通过电子邮件向所有参与者发送 D-CFAR 活动新闻来改善芝加哥 D-CFAR 参与者之间的沟通，5) 开发艾滋病毒教育材料的获取途径， 6) 制定沟通策略，将艾滋病毒/艾滋病研究的进展带给社区； 7) 建立基础设施，使我们能够从 D-CFAR 转向 CFAR。我们将通过创建核心和重点领域来实现这些目标。将有： 行政核心（艾伦·兰迪博士和琳达·鲍姆博士）；发展核心（Greg Spear 博士和 Ron Hershow 博士）；基础科学核心（Michael Caffrey 博士和 James Bremer 博士）；临床核心（Audrey French 博士和 Richard Novak 博士）；以及社会和行为科学核心（朱迪思·利维博士和罗伯特·贝利博士）。我们将积极推动以下领域的研究：艾滋病毒与妇女（凯瑟琳·韦伯女士）；艾滋病毒与衰老（Pauline Maki 博士）和药物滥用与艾滋病毒（Celeste Napier 博士）。

项目成果

Penile coital injuries in men decline after circumcision: Results from a prospective study of recently circumcised and uncircumcised men in western Kenya.

• DOI: 10.1371/journal.pone.0185917
• 发表时间: 2017
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Westercamp N;Mehta SD;Jaoko W;Okeyo TA;Bailey RC
• 通讯作者: Bailey RC

Effects of cryopreservation on effector cells for antibody dependent cell-mediated cytotoxicity (ADCC) and natural killer (NK) cell activity in (51)Cr-release and CD107a assays.

• DOI: 10.1016/j.jim.2014.01.017
• 发表时间: 2014-04
• 期刊: Journal of immunological methods
• 影响因子: 2.2
• 作者: Mata MM;Mahmood F;Sowell RT;Baum LL
• 通讯作者: Baum LL

Should male circumcision be advocated for genital cancer prevention?

是否应该提倡男性包皮环切术来预防生殖器癌症？

• DOI: 10.7314/apjcp.2012.13.9.4839
• 发表时间: 2012
• 期刊: Asian Pacific journal of cancer prevention : APJCP
• 作者: Morris,BrianJ;Mindel,Adrian;Tobian,AaronAr;Hankins,CatherineA;Gray,RonaldH;Bailey,RobertC;Bosch,Xavier;Wodak,AlexD
• 通讯作者: Wodak,AlexD

Voluntary medical male circumcision: an HIV prevention priority for PEPFAR.

• DOI: 10.1097/qai.0b013e31825cac4e
• 发表时间: 2012-08-15
• 期刊: Journal of acquired immune deficiency syndromes (1999)
• 作者: Reed JB;Njeuhmeli E;Thomas AG;Bacon MC;Bailey R;Cherutich P;Curran K;Dickson K;Farley T;Hankins C;Hatzold K;Justman J;Mwandi Z;Nkinsi L;Ridzon R;Ryan C;Bock N
• 通讯作者: Bock N

An effective, economical method of reducing environmental noise in the vivarium.

• 发表时间: 2011-07
• 期刊: Journal of the American Association for Laboratory Animal Science : JAALAS
• 作者: Maggie T Young;Alan L. French;J. Clymer