Development of a Clinically Viable Pattern Recognition Embedded System

临床上可行的模式识别嵌入式系统的开发

• 批准号: 8831819
• 负责人: Blair Lock
• 金额: $ 47.45万
• 依托单位: COAPT, LLC
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8831819
• 关键词: Adopted; Agonist; Algorithms; Amputees; Appearance; Back; Benchmarking; Bionics; Boston; Caring; Chicago; Clinic; Clinical; Complex; Computer software; Contracts; Data; Development; Devices; Disabled Persons; Documentation; Elbow; Elements; Engineering; Fostering; Freedom; Future; Goals; Grant; Hand; Health; Home environment; Hour; Impairment; Institutes; Intellectual Property; Joints; Knowledge; Laboratories; Licensing; Limb Prosthesis; Measures; Medicine; Mission; Motion; Muscle; Myoelectric prosthesis; Outcomes Research; Pathway interactions; Patient Education; Patients; Pattern; Pattern Recognition; Persons; Phase; Physical Medicine; Population; Process; Productivity; Prosthesis; Protocols documentation; Public Health; Quality Control; Quality of life; Rehabilitation Research; Rehabilitation therapy; Research; Research Personnel; Signal Transduction; Site; Staging; System; Techniques; Technology; Testing; Time; Touch sensation; Training; Upper Extremity; Work; Wrist; arm; base; clinical application; clinical research site; design; digital; disability; flexibility; graphical user interface; improved; improved functioning; limb amputation; novel; public health relevance; reinnervation; research clinical testing

DESCRIPTION (provided by applicant): Pattern recognition (PR) myoelectric control systems can dramatically improve an amputee patient's control of a powered prosthesis, but they have not been made commercially available. Coapt, LLC, is a start-up stage company that has initiated a controlled commercial release of PR myoelectric control for the benefit of upper- limb amputees. The controller is based on research completed by the Center for Bionic Medicine at the Rehabilitation Institute of Chicago (RIC) and has been widely developed and tested with transradial and higher-level amputees. Coapt has previously licensed valuable PR controller technology and intellectual property from the RIC. Upper-limb amputees are faced with significant impairment and have not previously benefitted from the advances in PR control technology. Conveniently, commercially available multifunction prostheses are now available that offer users multiple powered options but these are not presently enabled with PR control. The long-term goal is to provide upper-limb amputees with a more intuitive option for controlling their externally powered prostheses. The objective of this application is to make the initially released commercial product intuitive enough that it can reliably work across a variety of sites and manufactures with minimal on-site engineering time. Coapt's first product is an advanced PR microcontroller system that can 'drive' any existing or future prosthetic arm system by interpreting electromyographic (EMG) signal patterns. An important factor in the development of such a broad reaching approach is reaching as many amputee patients as possible. To achieve consumer acceptance, the product offering must be realized according to the needs and practices of the prosthetic practitioner. This application comprises the following three specific aims: (1) develop a clinically focused software package; (2) complete in laboratory testing of commercially available multifunction arm systems; and (3) evaluate quantitative data regarding the fitting process and resulting prosthesis usage in take- home settings across multiple sites. Under the first aim the clinician-facing elements of the system's configuration software will be implemented with iterative clinical evaluations. Under the second aim, the PR controller system will be configured to enhance the control of commercially available multifunction hand prostheses on amputee subjects. The third aim will provide valuable information that we can compare against bench-mark data from conventional control usage, which in turn will inform future design decisions. The proposed research is significant because it enables a pathway to connect pattern recognition-based myoelectric control with commercially available multifunction prostheses from being adopted. Ultimately, this research will help upper-limb amputees to dramatically improve the control of their prostheses, allowing for an improved quality of life and promote return to work in many cases.

描述（由申请人提供）：模式识别（PR）肌电控制系统可以显着改善截肢者对驱动假体的控制，但尚未商业上可用。 Coapt，LLC是一家启动舞台公司，启动了PR Myoelectric Control的受控商业版本，以造福上肢Amputees。该控制者基于芝加哥康复研究所（RIC）的仿生中心完成的研究，并通过跨学院和高级截肢者进行了广泛的开发和测试。 Coapt以前已从RIC获得了有价值的PR控制器技术和知识产权。上限上的截肢者面临重大损害，以前尚未从公关控制技术的进步中受益。现在可以方便，可商购的多功能假体为用户提供多个动力选项，但目前没有PR控件启用这些选项。长期的目标是为上限上的截肢者提供控制其外部动力假体的更直观的选择。该应用程序的目的是使最初发布的商业产品足够直观，以至于它可以在各种站点和制造商中可靠地工作，以最少的现场工程时间。 Coapt的第一个产品是一种先进的PR微控制器系统，可以通过解释肌电图（EMG）信号模式来“驱动”任何现有或将来的假肢系统。开发这种广泛的接触方法的重要因素是达到尽可能多的截肢者患者。为了获得消费者的接受，必须根据假体从业者的需求和实践来实现产品。该应用程序包括以下三个特定目的：（1）开发一个以临床为中心的软件包； （2）完成市售多功能臂系统的实验室测试； （3）评估有关拟合过程的定量数据以及在多个站点的带房屋中的假体使用情况。在第一个目标下，将通过迭代临床评估来实施系统配置软件的临床医生元素。在第二个目标下，将配置PR控制器系统，以增强截肢受试者对市售多功能手术的控制。第三个目标将提供有价值的信息，我们可以将传统控制使用情况与基准标记数据进行比较，这反过来将为未来的设计决策提供信息。拟议的研究很重要，因为它可以使一条将基于模式识别的肌电控制与可获得的多功能假体连接起来的途径。最终，这项研究将有助于上限截肢者大大改善其假体的控制，从而改善生活质量，并在许多情况下促进工作重返工作。