UltraSonic Spirometer for Home Monitoring of Asthma Patients

用于家庭监测哮喘患者的超声波肺活量计

• 批准号: 8251860
• 负责人: Patrick Lichter
• 金额: $ 17.95万
• 依托单位: KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-15 至 2014-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8251860
• 关键词: Accident and Emergency department; Address; Affect; Air; American; Asthma; Biomedical Technology; Calibration; California; Chronic; Chronic Disease; Clinical; Communication; Data; Data Collection; Development; Devices; Diagnostic; Electronics; Engineering; Environmental Risk Factor; Glosso-Sterandryl; Goals; Health; Healthcare Systems; Home environment; Human; Internet; Lung; Maintenance; Marketing; Measurement; Measures; Medical; Medical Device; Monitor; Operative Surgical Procedures; Patients; Personal Health Services; Phase; Physicians; Principal Investigator; Pulmonary Function Test/Forced Expiratory Volume 1; Research; Research Personnel; Severities; Solutions; Spirometry; Surveys; System; Techniques; Technology; Test Result; Testing; Time; Transplantation; Ultrasonics; Universities; Variant; Visit; Wireless Technology; airway inflammation; airway obstruction; base; cost; design; experience; human study; innovation; medical schools; meter; pressure; professor; programs; prototype; pulmonary function; respiratory; sensor; skills; tool; transmission process; usability

DESCRIPTION (provided by applicant): Koronis Biomedical Technologies Corporation (KBT) proposes to develop a spirometer device targeted toward home-based monitoring of asthma patients. Spirometry has well established advantages over peak flow meters for the monitoring of pulmonary function in asthma patients, yet current spirometer solutions are not optimized for home monitoring applications. They require expensive calibrated components to provide accurate results due unwanted sensitivities to manufacturing variations in their air-flow sensing sensors and to manufacturing variations in spirometer mouthpieces. This calibration requirement has dramatic implications for potential home users, including significant maintenance burdens and complicated usage requirements. Ultrasonic air-flow technology is not susceptible to these limitations because unlike current technology, which infers air-flow from pressure sensors, ultrasonic techniques directly measure air-flow rates. In this project KBT will develop a low- maintenance easy-to-use ultrasonic spirometer for the home management market. The device will feature an integrated Bluetooth wireless interface to enable the convenient transmission of spirometer test results to Internet connected devices for transmission to medical doctors and respiratory therapists, or to personal health services like Google Health and Microsoft Health Vault. The objective of this phase I project is to build and test a prototype ultrasonic spirometer and develop a smartphone application to track the results and transfer them to a Google Health. The utility of the system will be determined via spirometric accuracy tests and an end-user study conducted with medical doctors and respiratory therapists with expertise in asthma monitoring and home management of patients. PUBLIC HEALTH RELEVANCE: Recent advances in sensor technology enable the development of a spirometer optimized for in-home monitoring. The introduction of ultrasonic flow metering allows the creation of a low-maintenance easy-to-use spirometer. This innovation will dramatically lower the cost per test and will have the immediate impact of introducing diagnostic spirometry for in-home monitoring to asthma and other patients. This advanced spirometer will leverage wireless communication technology to enable the development of a zero-skill spirometer optimized for home monitoring applications.

描述（由申请人提供）：Koronis Biomedical Technologies Corporation (KBT) 提议开发一种肺活量计装置，旨在对哮喘患者进行家庭监测。在监测哮喘患者的肺功能方面，肺量计比峰值流量计具有明显的优势，但当前的肺量计解决方案并未针对家庭监测应用进行优化。它们需要昂贵的校准组件来提供准确的结果，因为气流传感传感器的制造变化和肺活量计接口的制造变化具有不必要的敏感性。这种校准要求对潜在的家庭用户具有巨大的影响，包括巨大的维护负担和复杂的使用要求。超声波气流技术不易受到这些限制的影响，因为与从压力传感器推断气流的当前技术不同，超声波技术直接测量气流速率。在该项目中，KBT 将为家庭管理市场开发一种低维护、易于使用的超声波肺活量计。该设备将配备集成蓝牙无线接口，可以方便地将肺活量计测试结果传输到互联网连接设备，以便传输给医生和呼吸治疗师，或传输给 Google Health 和 Microsoft Health Vault 等个人健康服务。第一阶段项目的目标是构建和测试原型超声波肺活量计，并开发智能手机应用程序来跟踪结果并将其传输到 Google Health。该系统的实用性将通过肺活量准确性测试以及由具有哮喘监测和患者家庭管理专业知识的医生和呼吸治疗师进行的最终用户研究来确定。 公共健康相关性：传感器技术的最新进展使得开发出适合家庭监测的肺活量计成为可能。超声波流量计量的引入可以创建低维护且易于使用的肺活量计。这项创新将大大降低每次测试的成本，并将对引入诊断性肺活量测定法对哮喘和其他患者进行家庭监测产生直接影响。这种先进的肺活量计将利用无线通信技术来开发针对家庭监测应用而优化的零技能肺活量计。