2012 Lipoprotein Metabolism Gordon Research Conference and Gordon Research Semina

2012年脂蛋白代谢戈登研究会议暨戈登研究研讨会

• 批准号: 8318336
• 负责人: ROBERT O'Mara RYAN
• 金额: $ 1.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-15 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8318336
• 关键词: ATP-Binding Cassette Transporters; Accounting; Address; African American; American; Animal Model; Apolipoproteins B; Area; Atherosclerosis; Basic Science; Biochemistry; Bioinformatics; Biological; Biological Models; Biology; Cardiovascular Diseases; Cells; Cholesterol; Cholesterol Homeostasis; Clinical; Commit; Consultations; Development; Diagnosis; Disease; Dyslipidemias; Ensure; Event; Family member; Fostering; Gender; Generations; Genetic; Genomics; Goals; Health; Human; Individual; International; Interpersonal Relations; Knowledge; Lipids; Lipolysis; Lipoproteins; Low Density Lipoprotein Receptor; Metabolism; Mission; Molecular; National Heart, Lung, and Blood Institute; Oral; Participant; Pathway interactions; Patients; Pharmaceutical Preparations; Plasma; Postdoctoral Fellow; Prevention; Primary Prevention; Process; Proteomics; Public Health; Qualifying; Regulation; Reporting; Research; Research Personnel; Residual state; Resort; Risk; Role; Schedule; Science; Scientist; Secondary Prevention; Systems Analysis; Technology; Therapeutic; Time; Training; Translating; Translational Research; Translations; Woman; Work; abstracting; cardiovascular risk factor; career development; design; graduate student; high density lipoprotein-3; human disease; human population study; improved; interest; knowledge base; lipid metabolism; lipid transport; meetings; member; metabolomics; novel therapeutic intervention; particle; posters; programs; public health relevance; social; success; symposium; unpublished works

DESCRIPTION (provided by applicant): We request partial support of the 2012 Gordon Research Conference on Lipoprotein Metabolism to be held at Waterville Valley Resort, NH on June 17 - 22 in conjunction with a Gordon Research Seminar (June 16-17). The Chair, Dr. Robert Ryan, in consultation with past chairs, the 2014 vice chairs, and leaders in the field, have planned nine oral sessions: Session 1: The Control of Lipolysis in Plasma Session 2: Regulation of Cholesterol Homeostasis Session 3: High-density lipoprotein: impact of particle diversity Session 4: Apolipoprotein B and TG-rich Lipoprotein Assembly Session 5: Expanding Role of Low Density Lipoprotein Receptor Family Members Session 6: Cholesterol efflux, ABC Transporters and Disease Session 7: Advances in Therapies to Treat Cardiovascular Disease Session 8: Intracellular Lipid Transport and Lipid Droplet Biology Session 9: State of the Art: Genomics, Proteomics and Metabolomics Our conference satisfies all aspects of the NHLBI Mission. First, we bring together international leaders in lipoprotein metabolism, a mechanism that accounts for 30% of global cardiovascular risk burden. Second, gender-related issues of genetics, biology, biochemistry and clinical manifestations of lipoproteins have been identified, so our conference satisfies the NHLBI responsibility for addressing these issues in women. Two Discussion Leaders are women, and an African-American, Dr. Debose-Boyd, will be a major speaker in Session 2. Our conference has been carefully coordinated to include diversity of research related to the causes, prevention, diagnosis and treatment of dyslipidemias and cardiovascular disease. Fourth, the NHLBI has traditionally supported our meeting and we have been honored to invite selected members of NHLBI administration as attendees. Fifth, we share the NHLBI's priority on prevention; indeed key aspects of primary and secondary prevention of cardiovascular disease that are currently in widespread routine clinical use (e.g. statin drugs) were first reported at our past meetings. Sixth, the Chair has placed the highest priority on participation by individuals early in their training and early in their career development. The Gordon Research Seminar component will have four sessions (to be finalized after the review of submitted abstracts) with presentations by young investigators.

描述（由申请人提供）：我们请求对将于 6 月 17 日至 22 日在新罕布什尔州沃特维尔谷度假村举行的 2012 年戈登脂蛋白代谢研究会议以及戈登研究研讨会（6 月 16 日至 17 日）提供部分支持。主席 Robert Ryan 博士在与前任主席、2014 年副主席以及该领域的领导者协商后， 计划九场口头会议： 第 1 场：血浆中脂解的控制 第 2 场：胆固醇稳态的调节 第 3 场：高密度脂蛋白：颗粒多样性的影响 第 4 场：载脂蛋白 B 和富含 TG 的脂蛋白组装 第 5 场：扩大脂蛋白的作用低密度脂蛋白受体家族成员第 6 场：胆固醇外流、ABC 转运蛋白和疾病第 7 场：进展心血管疾病治疗第 8 场：细胞内脂质转运和脂滴生物学第 9 场：最新技术：基因组学、蛋白质组学和代谢组学 我们的会议满足了 NHLBI 使命的各个方面。首先，我们汇集了脂蛋白代谢领域的国际领先者，脂蛋白代谢机制占全球心血管风险负担的 30%。其次，脂蛋白的遗传学、生物学、生物化学和临床表现等与性别相关的问题已经得到确定，因此我们的会议满足了 NHLBI 解决女性这些问题的责任。两位讨论领袖都是女性，一位非裔美国人 Debose-Boyd 博士将在第二场会议上担任主要发言人。我们的会议经过精心协调，涵盖了与血脂异常的病因、预防、诊断和治疗相关的多样性研究和心血管疾病。第四，NHLBI 历来支持我们的会议，我们很荣幸邀请 NHLBI 管理部门的选定成员作为与会者。第五，我们赞同 NHLBI 的预防优先原则；事实上，目前临床广泛使用的心血管疾病一级和二级预防的关键方面（例如他汀类药物）是在我们过去的会议上首次报告的。第六，主席高度重视个人在培训和职业发展早期的参与。戈登研究研讨会部分将有四场会议（将在审查提交的摘要后最终确定），由年轻研究人员进行演讲。