HIV/STD Prevention Program for African American Males

非裔美国男性艾滋病毒/性病预防计划

• 批准号: 8410036
• 负责人: Stephen B. Kennedy
• 金额: $ 37.66万
• 依托单位: PACIFIC INSTITUTE FOR RES AND EVALUATION
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8410036
• 关键词: Accounting; Acquired Immunodeficiency Syndrome; African American; Behavioral; Biological; Centers for Disease Control and Prevention (U.S.); Cessation of life; Characteristics; Chicago; Coitus; Communities; Computer Assisted; Data; Equilibrium; Ethics; Evaluation Research; Frequencies; Funding; HIV; Human immunodeficiency virus test; Illinois; Intervention; Intervention Studies; Interview; Kentucky; Low income; Mediating; Minority; Newly Diagnosed; Outcome; Participant; Patient Self-Report; Phase; Pilot Projects; Population; Prevention program; Prevention strategy; Process; Public Health; Public Housing; Quality of life; Randomized; Recruitment Activity; Relative (related person); Reporting; Research; Research Institute; Research Personnel; Self Efficacy; Series; Sex Behavior; Sexually Transmitted Diseases; Side; Site; Target Populations; United States; United States National Academy of Sciences; United States National Institutes of Health; Universities; Variant; Youth; aged; arm; comparison group; condoms; disorder prevention; experience; health disparity; high risk sexual behavior; informant; intervention program; male; minority health; primary outcome; programs; randomized trial; research study; secondary outcome; young adult

DESCRIPTION (provided by the applicant): Common use of condoms by young adults across all racial/ethic groups remains a formidable public health challenge, especially for African American males (Kennedy et al., 2007a,b,c; Kennedy et al., under review). As a call to action, a collaborative team of researchers proposes to conduct a four-year behavioral-driven research study to modify, implement and evaluate the efficacy of a promising brief condom promotion program in a two-arm randomized trial among African American males 18-24 years from 12 community centers on Chicago's South Side. Accordingly, we propose the following specific aims and related set of research questions: 1. Modify, implement, and assess the efficacy of a condom promotion program for African American males. 1.1. Will participants randomly assigned to the intervention report a statistically significant increase in the frequency of condom use and decrease in unprotected sexual intercourse (primary outcomes) relative to those assigned to the comparison group? 1.2. Will the intervention produce statistically significant positive effects on secondary outcomes (e.g., condom use self-efficacy, condom use decisional balance, etc.) relative to the comparison group? 1.3. Will the secondary outcomes mediate the relationship between intervention status and condom use (the primary outcome)? 2. Assess characteristics of program implementation and its relationship to changes in behavioral outcomes. 2.1. What was the level of implementation fidelity? 2.2. How is variation in implementation fidelity related to change in primary outcomes? For a nine-month formative phase, we will conduct a series of qualitative interviews with key informants and the target population to modify our existing program. Over the next 16 months, we will recruit 520 study participants from our recruitment sites to implement the intervention and comparison programs and assess the efficacy of the intervention program on a series of primary and secondary outcomes. Assuming 30% attrition rate (n=156), we expect to collect complete outcome data via Audio Computer Assisted Self Interview (ACASI) from about 364 participants over 12-months. In addition, we will conduct biological assessment of STDs to validate participants' self-reports on sexual behaviors at all assessment points. This proposed study is an extension of a recently completed NIH-funded R21 (PI: Kennedy) to develop, implement, and pilot a brief condom promotion program for African American males (Kennedy et al., 2007a,b,c; Kennedy et al., under review). We have assembled a collaborative team of experienced investigators and research partners to successfully implement this proposed project.

描述（由申请人提供）：年轻人在所有种族/道德群体中对避孕套的共同用途仍然是一个巨大的公共卫生挑战，尤其是对于非裔美国人男性（Kennedy等，2007a，2007a，b，c; Kennedy等人，正在审查中）。作为行动呼吁，一个合作的研究人员提议进行四年的行为驱动研究研究，以在芝加哥南侧的12个社区中心对18 - 24年的非裔美国人男性进行了两臂随机试验的有希望的简短避孕套促进计划的疗效。因此，我们提出了以下特定目的和相关的研究问题集： 1。修改，实施和评估非裔美国男性避孕套促进计划的功效。 1.1。与分配给比较组的参与者报告的参与者是否会随机分配到干预措施报告避孕套使用频率和不受保护的性交（主要结果）的统计学上显着增加？ 1.2。相对于比较组，干预措施是否会对次级结果（例如，使用避孕套使用自我效能感，使用避孕套使用决策平衡等）产生统计学上的显着积极影响？ 1.3。次要结果是否会介导干预状态和使用避孕套之间的关系（主要结果）？ 2。评估计划实施的特征及其与行为结果变化的关系。 2.1。实施水平是多少？ 2.2。实施保真度的变化与主要结果的变化有关？在一个九个月的形成阶段，我们将对关键线人和目标人群进行一系列定性访谈，以修改我们的现有计划。在接下来的16个月中，我们将从招聘站点招募520名研究参与者，以实施干预和比较计划，并评估干预计划对一系列主要和次要结果的疗效。假设损耗率为30％（n = 156），我们希望通过音频计算机辅助自我访谈（ACASI）从大约364个以上的参与者那里收集完整的结果数据。此外，我们还将对性病进行生物学评估，以验证参与者在所有评估点上关于性行为的自我报告。这项拟议的研究是最近完成的NIH资助的R21（PI：Kennedy）开发，实施和试行非裔美国人男性的简短避孕套促进计划的扩展（Kennedy等，2007a，B，C; Kennedy等人，正在审查中）。我们组建了一个由经验丰富的研究人员和研究合作伙伴组成的合作团队，以成功地实施该建议的项目。