Protocol Specific

协议特定

• 批准号: 8250423
• 负责人: HOWARD H. BAILEY
• 金额: $ 11.7万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8250423
• 关键词: Clinical; Clinical Research; Clinical Research Protocols; Clinical Trials Network; Comprehensive Cancer Center; Data; Databases; Development; Funding; Grant; Lead; Methods; Monitor; Nursing Research; Peer Review; Performance; Phase; Pilot Projects; Protocols documentation; Recording of previous events; Reporting; Research; Research Personnel; Research Priority; Research Support; Staging; Translational Research; Wisconsin; base; data management; flexibility; innovation; member; novel; oncology; programs; research study; translational study

The UWCCC proposes to have available for its members Protocol Specific Research support for pilot clinical/translational research studies that would benefit from timely funding. The UWCCC has a long history of funding pilot studies that have led to more timely clinical research and NCI funding. The UWCCC has funded 15 (8 of these ongoing or recently initiated) early phase pilot clinical studies over the last grant period with an accrual of 173 subjects. Efficient accrual to UWCCC-supported studies is enhanced by the UWCCC-supported statewide clinical trials network (Wisconsin Oncology Network). This method of support allows investigators with emerging ideas or promising initial pilot data to apply for the support of a research nurse and data manager to conduct high priority, innovative, feasibility and early stage institutional clinical research protocols. Proposals will be requested twice yearly and will undergo peer-review (under the direction of Associate Directors H. Bailey and P. Sondel) with selection based on scientific merit, need for Protocol Specific Research funding, potential to lead to NCI funding, and UWCCC research priorities. Once selected, protocols receive research nurse/data management support from this mechanism and all the necessary developmental and regulatory support via the Oncore database for UWCCC-required monitoring and reporting.

UWCCC 建议为其成员提供针对试点的协议特定研究支持 受益于及时资助的临床/转化研究。 UWCCC历史悠久 资助试点研究，这些研究导致了更及时的临床研究和 NCI 资助。 UWCCC 有 在上一个资助期内资助了 15 项（其中 8 项正在进行或最近启动）早期试点临床研究 累计173个科目。 UWCCC 支持的研究的有效累积通过 UWCCC 支持的全州临床试验网络（威斯康星肿瘤网络）。这种支持方法 允许具有新兴想法或有希望的初步试点数据的研究人员申请研究支持 护士和数据经理进行高优先级、创新性、可行性和早期机构临床 研究协议。提案将每年两次提出申请，并将接受同行评审（根据 副主任 H. Bailey 和 P. Sondel 的指导），根据科学价值、需要进行选择 协议特定研究资助、获得 NCI 资助的潜力以及 UWCCC 研究重点。一次 选择后，方案将获得该机制和所有研究护士/数据管理的支持 通过 Oncore 数据库为 UWCCC 所需的监测提供必要的开发和监管支持 和报告。