Symptom Management and Palliative Care Research in Adults with Advanced Disease

成人晚期疾病的症状管理和姑息治疗研究

• 批准号: 8472723
• 负责人: Barbara Daly
• 金额: $ 21.38万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8472723
• 关键词: Adult; Palliative Care; Research; advanced disease; symptom management

DESCRIPTION (provided by applicant): This application for a T32 predoctoral and postdoctoral training program describes a proposed plan for training in symptom management and palliative care research among adults with advanced disease - specifically cancer, heart failure, and chronic critical illness. The long-term goal of this training program is to train a diverse group nurse scientists who will advance our knowledge and understanding of how to provide effective palliation - - that is, management of symptoms - - that significantly impair quality of life in advanced and incurable disease states. Symptom management investigations are especially challenging in subject populations who have life-limiting, progressive disease, yet these are also the patients usually in greatest need of expert symptom management. In addition to measurement and instrument issues specific to single symptoms (e.g. pain, dyspnea), identifying appropriate end points in the context of disease progression, the high likelihood of missing data from subjects who are quite ill, and accounting for the effects of co-existing depression and anxiety when measuring physical symptoms are common challenges in this population. In order to advance our understanding of symptom management approaches and build the evidence base needed for effective palliative care, specific tailored preparation in methodologies and analytic strategies needed for research with persons with progressive, advanced illness are essential. This training program will address that need. This NRSA will provide support for 8 predoctoral trainees and 9 post-doctoral trainees over the 5 years of the program. In addition to our typical applicant pool, we will particularly target BSN students for entry to the "fast-track" BSN-to-PhD program and members of minority groups. We have an existing internal program to identify promising BSN students in our school who demonstrate exceptional potential for moving directly in to a doctoral program. Our faculty also have leadership roles in national specialty organizations with large BSN memberships, and these will provide additional recruitment opportunities. Through our existing relationships with several colleges that have large minority student populations, we will be able to target recruitment to achieve a demographic balance in the training program. We have established collaborative relationships with a variety of accomplished researchers from other disciplines who will be active faculty participants on this training program. Both the pre- and postdoctoral training plans are built on a successful record of recruitment and productivity of previous graduates and we believe the focus of the proposed program will enable trainees to make significant contributions to this important area of nursing science.

描述（由申请人提供）：T32前和博士后培训计划的申请描述了拟议的症状管理培训和姑息治疗研究的计划，其中患有晚期疾病的成年人，特别是癌症，心力衰竭，心力衰竭和慢性重症疾病。该培训计划的长期目标是培训一名多样化的团体护士科学家，他们将提高我们对如何提供有效抚慰的了解和理解 - 即症状的管理 - 这会严重损害高级和无法治愈的生活质量疾病状态。症状管理调查在患有生命的，进行性疾病的受试者人群中尤其具有挑战性，但这些患者通常是最需要专家症状管理的患者。除了针对单一症状的测量和仪器问题（例如疼痛，呼吸困难），在疾病进展的背景下确定了适当的终点，很可能丢失了病情病情的受试者的数据可能很可能，并考虑了共同的影响的影响。在测量身体症状时，现有的抑郁症和焦虑是该人群的常见挑战。为了促进我们对症状管理方法的理解，并建立有效姑息治疗所需的证据基础，在方法论和与患有进步，晚期疾病的人进行研究中所需的特定量身定制的准备工作至关重要。该培训计划将解决需求。 该NRSA将在该计划的5年内为8位占主导地位的学员和9名博士后学员提供支持。除我们的典型申请人池外，我们还将特别针对BSN学生进入“快速轨道” BSN到PHD计划和少数群体成员。我们有一个现有的内部计划来确定学校中有希望的BSN学生，他们表现出直接进入博士课程的极大潜力。我们的教职员工在拥有大型BSN成员资格的国家专业组织中还担任领导职务，这些组织将提供更多的招聘机会。通过我们与几所拥有少数学生人数的大学的现有关系，我们将能够以招聘为目标，以实现培训计划中的人口平衡。我们已经与其他学科的各种有成就的研究人员建立了合作关系，这些研究人员将成为该培训计划的积极教师。前和博士后培训计划 建立在以前毕业生的招聘和生产力的成功记录的基础上，我们相信拟议计划的重点将使学员能够为这一重要的护理科学领域做出重大贡献。