Symptom Management and Palliative Care Research in Adults with Advanced Disease

成人晚期疾病的症状管理和姑息治疗研究

• 批准号: 8875492
• 负责人: Barbara Daly
• 金额: $ 40.2万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8875492
• 关键词: Adult; Palliative Care; Research; advanced disease; symptom management

DESCRIPTION (provided by applicant): This application for a T32 predoctoral and postdoctoral training program describes a proposed plan for training in symptom management and palliative care research among adults with advanced disease - specifically cancer, heart failure, and chronic critical illness. The long-term goal of this training program is to train a diverse group nurse scientists who will advance our knowledge and understanding of how to provide effective palliation - - that is, management of symptoms - - that significantly impair quality of life in advanced and incurable disease states. Symptom management investigations are especially challenging in subject populations who have life-limiting, progressive disease, yet these are also the patients usually in greatest need of expert symptom management. In addition to measurement and instrument issues specific to single symptoms (e.g. pain, dyspnea), identifying appropriate end points in the context of disease progression, the high likelihood of missing data from subjects who are quite ill, and accounting for the effects of co-existing depression and anxiety when measuring physical symptoms are common challenges in this population. In order to advance our understanding of symptom management approaches and build the evidence base needed for effective palliative care, specific tailored preparation in methodologies and analytic strategies needed for research with persons with progressive, advanced illness are essential. This training program will address that need. This NRSA will provide support for 8 predoctoral trainees and 9 post-doctoral trainees over the 5 years of the program. In addition to our typical applicant pool, we will particularly target BSN students for entry to the "fast-track" BSN-to-PhD program and members of minority groups. We have an existing internal program to identify promising BSN students in our school who demonstrate exceptional potential for moving directly in to a doctoral program. Our faculty also have leadership roles in national specialty organizations with large BSN memberships, and these will provide additional recruitment opportunities. Through our existing relationships with several colleges that have large minority student populations, we will be able to target recruitment to achieve a demographic balance in the training program. We have established collaborative relationships with a variety of accomplished researchers from other disciplines who will be active faculty participants on this training program. Both the pre- and postdoctoral training plans are built on a successful record of recruitment and productivity of previous graduates and we believe the focus of the proposed program will enable trainees to make significant contributions to this important area of nursing science.

描述（由申请人提供）：这份 T32 博士前和博士后培训计划申请描述了一项针对患有晚期疾病（特别是癌症、心力衰竭和慢性危重疾病）的成年人进行症状管理和姑息治疗研究培训的拟议计划。该培训计划的长期目标是培训多元化的护士科学家群体，他们将提高我们对如何提供有效的姑息治疗（即症状管理）的知识和理解，这些症状会严重损害晚期和无法治愈的患者的生活质量疾病状态。对于患有生命有限、进展性疾病的受试者群体，症状管理调查尤其具有挑战性，但这些患者通常也是最需要专家症状管理的患者。除了特定于单一症状（例如疼痛、呼吸困难）的测量和仪器问题外，在疾病进展的背景下确定适当的终点、病情严重的受试者数据丢失的可能性很高，并考虑了共同症状的影响。在测量身体症状时存在的抑郁和焦虑是该人群面临的常见挑战。为了增进我们对症状管理方法的理解并建立有效姑息治疗所需的证据基础，对患有进展性晚期疾病的人进行研究所需的专门定制的方法和分析策略准备至关重要。该培训计划将满足这一需求。 该 NRSA 将在该项目的 5 年里为 8 名博士前培训生和 9 名博士后培训生提供支持。除了我们典型的申请者群体之外，我们还将特别针对进入“快速通道”BSN 到博士项目的 BSN 学生和少数群体成员。我们现有一个内部计划，旨在识别我们学校有前途的 BSN 学生，这些学生表现出直接进入博士课程的特殊潜力。我们的教师还在拥有大量 BSN 会员的国家专业组织中担任领导职务，这将提供额外的招聘机会。通过我们与几所拥有大量少数族裔学生的大学的现有关系，我们将能够有针对性地招募人员，以实现培训计划中的人口平衡。我们与来自其他学科的众多卓有成就的研究人员建立了合作关系，他们将成为该培训计划的积极教员参与者。博士前和博士后培养计划 建立在以前毕业生的成功招聘和生产力记录的基础上，我们相信拟议计划的重点将使学员能够为护理科学的这一重要领域做出重大贡献。