A Tailored Internet Intervention for Skin Cancer Risk Reduction in Young Adults

降低年轻人皮肤癌风险的定制互联网干预措施

• 批准号: 8230588
• 负责人: Carolyn Heckman
• 金额: $ 37.97万
• 依托单位: FOX CHASE CANCER CENTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-01 至 2013-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8230588
• 关键词: Adolescent; Adult; Age; Appearance; Behavior; Behavioral; Belief; Conscious; Diagnosis; Ethnic Origin; Exposure to; Face; Family history of; Foundations; Generic Drugs; Goals; Health behavior; Healthy People 2020; Image; Individual; Internet; Intervention; Knowledge; Literature; Locales; Longevity; Malignant Neoplasms; Mediating; Mediator of activation protein; Modeling; Motivation; Outcome; Participant; Population; Prevention; Public Health; Race; Randomized; Randomized Controlled Trials; Research; Risk; Risk Behaviors; Risk Factors; Risk Reduction; Sampling; Self Efficacy; Skin; Skin Cancer; Skin Carcinoma; Socioeconomic Status; Staging; Sun Exposure; Sunburn; Sunscreening Agents; Technology; Testing; Theoretical model; UV protection; Ultraviolet Rays; Woman; Work; age group; behavior change; cancer education; cancer risk; computerized; design; follow-up; high risk; improved; innovation; interactive multimedia; intervention effect; melanoma; modifiable risk; protective behavior; public health relevance; risk perception; sex; skin cancer prevention; therapy design; ultraviolet; ultraviolet damage; usability; web site; young adult

DESCRIPTION (provided by applicant): Skin cancer is the most common cancer in the US, with over a million new cases diagnosed yearly 1. Young adults, particularly women, are increasingly at risk of melanoma. Contributing to the increasing skin cancer risk among young adults is the fact that US adolescents have the lowest skin protection rates of all age groups 2 and also demonstrate increased exposure to natural and artificial UV radiation as they move into adulthood 3. Innovative interventions are needed to have an impact on skin cancer risk among young people. Unlike previous interventions, our skin cancer risk reduction intervention will be tailored (or personalized) to each individual participant and delivered via the Internet. The tailored intervention will emphasize appearance concerns, which are known to be the primary motivation for UV exposure and lack of skin protection among young adults. This will be accomplished in part through the use of personalized facial images showing UV damage as well as computerized age progression demonstrations. Primary Aim 1. To examine the efficacy of a tailored intervention delivered via the Internet designed to increase skin protection and decrease sun exposure behavior among young adults at moderate to high risk of developing skin cancer. Participants will be randomized to the tailored intervention, the Skin Cancer Foundation website, or an assessment only condition. Aim 2. To evaluate whether socio-demographic variables (sex, race/ethnicity, skin type, family history of skin cancer, education, socioeconomic status, and geographic locale), appearance consciousness, and past exposure and protective behaviors moderate intervention effects. Aim 3. To evaluate whether Integrative Model 4 constructs (UV-related knowledge, risk perception, beliefs, norms, self-efficacy, and intentions) mediate intervention effects. These mediators and the behavioral outcomes will be assessed at baseline as well as three weeks and three months post baseline. In the first stage of the project, the tailored intervention including interactive and multimedia materials will be developed and refined through acceptability and usability testing. In the second stage, the efficacy of the tailored intervention at improving UV exposure and protection behaviors will be evaluated in a randomized controlled trial conducted via the Internet. We will also establish moderators and mediators of intervention effects. The goals of future research would be to enhance the tailored intervention, for example, by adding additional contacts or Internet technologies or features, disseminate the intervention, assess the longevity of effects, and/or adapt the tailored intervention for use with other cancer risk behaviors or at risk groups. PUBLIC HEALTH RELEVANCE: Skin cancer is the most common cancer in the US, with over a million new cases diagnosed yearly. Innovative interventions are needed to have an impact on skin cancer risk. The purpose of the proposed project is to test a tailored intervention delivered via the Internet designed to reduce skin cancer risk behavior among young adults at moderate to high risk of developing skin cancer.

描述（由申请人提供）：皮肤癌是美国最常见的癌症，每年诊断出的新病例超过一百万例1。年轻人，尤其是女性，患黑色素瘤的风险越来越大。造成年轻人皮肤癌风险增加的原因是，美国青少年的皮肤保护率在所有年龄段中最低2，而且随着他们进入成年期，他们接触自然和人工紫外线辐射的机会也增加了3。需要创新的干预措施对年轻人皮肤癌的风险有影响。与以前的干预措施不同，我们的皮肤癌风险降低干预措施将为每个参与者量身定制（或个性化）并通过互联网提供。量身定制的干预措施将强调外表问题，众所周知，这是年轻人暴露于紫外线和缺乏皮肤保护的主要原因。这将部分通过使用显示紫外线损伤的个性化面部图像以及计算机化的年龄进展演示来实现。主要目标 1. 检验通过互联网提供的定制干预措施的功效，该干预措施旨在增强皮肤保护并减少中度至高风险患皮肤癌的年轻人的日晒行为。参与者将被随机分配到量身定制的干预措施、皮肤癌基金会网站或仅评估条件。目标 2. 评估社会人口变量（性别、种族/民族、皮肤类型、皮肤癌家族史、教育、社会经济地位和地理区域）、外表意识以及过去的接触和保护行为是否调节干预效果。目标 3. 评估综合模型 4 的构建（紫外线相关知识、风险感知、信念、规范、自我效能和意图）是否介导干预效果。这些中介因素和行为结果将在基线以及基线后三周和三个月进行评估。在项目的第一阶段，将通过可接受性和可用性测试来开发和完善包括交互式和多媒体材料在内的定制干预措施。在第二阶段，将通过互联网进行随机对照试验来评估定制干预措施在改善紫外线暴露和保护行为方面的效果。我们还将建立干预效果的调节者和中介者。未来研究的目标是加强量身定制的干预措施，例如，通过添加额外的联系人或互联网技术或功能，传播干预措施，评估效果的持久性，和/或调整定制的干预措施以用于其他癌症风险行为或高危人群。 公共卫生相关性：皮肤癌是美国最常见的癌症，每年诊断出超过一百万个新病例。需要创新的干预措施来降低皮肤癌风险。拟议项目的目的是测试通过互联网提供的定制干预措施，旨在减少中度至高风险患皮肤癌的年轻人的皮肤癌风险行为。