Imaging in 2020-VIII: Integrating Molecular Imaging and Complex Biology

2020-VIII 成像：分子成像与复杂生物学的整合

• 批准号: 8400285
• 负责人: Thomas J Meade
• 金额: $ 5.25万
• 依托单位: NORTHWESTERN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8400285
• 关键词: Address; Animal Model; Area; Biology; Cancer Diagnostics; Cells; Clinic; Collaborations; Communication; Complex; Development; Discipline; Education; Engineering; Environment; Fertilization; Fostering; Foundations; Goals; Image; Imaging technology; Individual; Institution; Intervention; Lead; Link; Location; Medicine; Molecular; Monitor; Neurosciences; Outcome; Participant; Pharmacology; Physiological; Physiology; Play; RNA Interference; Research; Research Personnel; Role; Scientist; Societies; Solutions; Stem cells; Structure; System; Systems Analysis; Systems Biology; Technology; Theoretical model; Wyoming; biological systems; cancer stem cell; cellular imaging; commune; distraction; flexibility; forest; innovation; meetings; member; molecular imaging; nanotherapeutic; new technology; novel therapeutics; success; symposium

DESCRIPTION (provided by applicant): The goal of Imaging in 2020 is to foster the development of enduring associations between numerous disciplines that will lead to innovative solutions and applications of imaging technologies. The proven "secret ingredient" for the success of previous I2020 meetings has been the diverse participants and location. These key components have successfully provided a unique opportunity for education between disciplines and lasting collaborations. This year (as for all past meetings) Imaging in 2020 VIII will be held at the Jackson Lake Lodge in Jackson Hole, Wyoming. This location in Grand Teton National Forest is easily accessible from Jackson Airport. Breathtaking views of the Grand Tetons provide a colorful backdrop and this environment has minimal distractions providing members the opportunity to commune with each other. PUBLIC HEALTH RELEVANCE: The theme of Imaging in 2020 for 2012, will be to explore the use of molecular imaging to understand complex biology. New links between molecular imaging and systems biology will be developed. A fundamental understanding of the biological systems in both normal and diseased physiology will play a critical role in the creation, monitoring and control of new highly potent interventions. With new therapeutic technologies such as RNA interference, nanotherapeutics and stem cells entering the clinic, a deeper understanding of underlying systems biology (that can only be attained through molecular imaging technology) is required. The meeting will address imaging of complexity in single cells, system pharmacology, cancer stem cells, immunological systems, animal and theoretical models to assess biological systems and the use of imaging in computational systems analysis. This year will expand the diversity of the scientists that gather in Jackson Hole to include systems biologists and mathematicians that will benefit from applying imaging technologies to their specific disciplines and, importantly, introduce new technologies and challenges for molecular imaging scientists. The focuses of the 2014 and 2016 meetings will be decided in June 2013 and June 2015 respectively. The chosen topics will be germane to the most up-to-date research in the field. The general themes will be the influence of molecular imaging in the areas of biology and medicine.

描述（由申请人提供）：2020 年成像的目标是促进众多学科之间持久关联的发展，从而带来成像技术的创新解决方案和应用。历届 I2020 会议成功的“秘诀”是参与者和地点的多元化。这些关键组成部分成功地为学科间​​教育和持久合作提供了独特的机会。今年（与过去的所有会议一样）2020 年第八届影像大会将在怀俄明州杰克逊霍尔的 Jackson Lake Lodge 举行。从杰克逊机场可轻松抵达大提顿国家森林的这个位置。大提顿国家公园的壮丽景色提供了丰富多彩的背景，这种环境中干扰最小，为成员提供了相互交流的机会。 公共卫生相关性：2020 年和 2012 年成像的主题将是探索利用分子成像来理解复杂的生物学。分子成像和系统生物学之间的新联系将得到发展。对正常和患病生理学中生物系统的基本了解将在新的高效干预措施的创建、监测和控制中发挥关键作用。随着RNA干扰、纳米治疗和干细胞等新治疗技术进入临床，需要对基础系统生物学（只能通过分子成像技术才能实现）有更深入的了解。会议将讨论单细胞复杂性成像、系统药理学、癌症干细胞、免疫系统、评估生物系统的动物和理论模型以及成像在计算系统分析中的应用。今年将扩大聚集在杰克逊霍尔的科学家的多样性，包括系统生物学家和数学家，他们将从将成像技术应用于其特定学科中受益，更重要的是，为分子成像科学家引入新技术和挑战。 2014年和2016年会议的重点将分别于2013年6月和2015年6月决定。所选主题将与该领域的最新研究密切相关。总体主题是分子成像在生物学和医学领域的影响。