CCR Bioinformatics Core

CCR 生物信息学核心

• 批准号: 8763786
• 负责人: David Goldstein
• 金额: $ 281.09万
• 依托单位: DIVISION OF BASIC SCIENCES - NCI
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8763786
• 关键词: ABCC1 gene; Area; Bioinformatics; Biological; CCR; Collaborations; Communities; Computer software; Consultations; Creativeness; Custom; Data; Data Analyses; Data Correlations; Databases; Development; Evaluation; Future; Housing; Human Resources; Laboratories; Manuscripts; Maps; Metadata; MicroRNAs; Microarray Analysis; Modeling; Outcome; Pathway interactions; Positioning Attribute; Publications; Reporting; Research; Research Infrastructure; Research Personnel; Resources; Schedule; Science; Scientist; Sequence Analysis; Services; Technology; United States National Institutes of Health; Update; Work; base; data integration; data mining; experience; improved; innovation; meetings; next generation sequencing; operation; posters; research study; web site

The CCRIFX is clearly meeting a critical subset of CCR bioinformatics needs, and the staff is continually improving the level of analysis support to the CCR community. It has become increasingly clear that most investigators have vastly underestimated the complexity involved with NGS analysis. The CCRIFX has positioned itself as the central resource for the analysis of NGS data. This is reflected in the fact that the number of publications involving the core's analysis is on the rise. At the end of 2011, the core was involved in one manuscript in development. As of March of this year (2013), the core is actively working as coauthors on at least 6 manuscripts with several more emerging as strong possibilities as research efforts mature. In addition, the core contributed as co-authors on 4 posters and was acknowledged in 2 manuscripts. Investigators have confirmed through post-service evaluations that the CCRIFX is helping to advance research efforts, contribute creativity and innovative thought as well as have a favorable impact on future publications. As expected, the sequencing technologies supported emphasize NGS as well as microarray technologies. A significant majority of requests involve data produced in-house. A substantial number of requests require external consultation with experts outside the core. Both ABCC and CCR bioinformatics personnel have provided critical expertise in regularly scheduled prioritization, status, and science meetings.

CCRIFX显然满足了CCR生物信息学需求的关键子集，并且员工正在不断提高对CCR社区的分析支持水平。越来越清楚的是，大多数研究人员都大大低估了NGS分析所涉及的复杂性。 CCRIFX已将自己定位为分析NGS数据的中心资源。这反映在以下事实中，涉及核心分析的出版物数量正在上升。在2011年底，核心参与了开发中的一个手稿。截至今年3月（2013年），核心正在积极地担任至少6个手稿的合着者，而这些手稿的出现又是研究工作成熟的强大可能性。此外，核心在4个海报上担任合着者，并在2个手稿中得到认可。调查人员通过服务后评估证实，CCRIFX正在帮助推进研究工作，贡献创造力和创新思想，并对未来的出版物产生有利的影响。正如预期的那样，测序技术支持强调NGS和微阵列技术。大部分请求涉及内部生产的数据。大量请求需要与核心外专家的外部咨询。 ABCC和CCR生物信息学人员都在定期安排的优先级，地位和科学会议方面提供了重要的专业知识。