Administrative Core

行政核心

• 批准号: 8376384
• 负责人: JOSEPH M MCCUNE
• 金额: $ 10.12万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-06-01 至 2015-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8376384
• 关键词: Address; Administrator; Area; Arts; Basic Science; Blood; California; Caring; Chronic Hepatitis C; Clinical; Clinical Investigator; Clinical Research; Decision Making; Disease; Elements; Ensure; Fostering; Future; General Hospitals; Grant; Hepatitis C; Hepatitis C virus; Human; Immune response; Immunologics; Immunologist; Interdisciplinary Study; Interferon-alpha; Medical center; National Institute of Allergy and Infectious Disease; Patients; Process; Research; Research Institute; Resources; Ribavirin; Role; San Francisco; Scientist; Site; Specialist; Structure; Technology; U-Series Cooperative Agreements; United States National Institutes of Health; Universities; Veterans; Work; authority; case control; cohort; cost; data sharing; design; flexibility; innovation; meetings; multidisciplinary; organizational structure; systems research

The Bay Area Hepatitis C Cooperafive Research Center (Bay Area HCV Center) will use cutfing-edge immunologic technologies in the context of well-designed and diverse retrospective case-control and prospecfive clinical cohorts to study the human immune response to HCV. We wish to ask the question: why is it that some respond well to standard-of-care therapy and some do not? To address this question, the Center will assemble a strong mulfidisciplinary team comprised of immunologists and clinical investigators at three different sites associated with the University of California at San Francisco (San Francisco General Hospital, UC Medical Center, and the San Francisco Veterans Affairs Medical Center), the California Pacific Medical Center, the Blood Systems Research Institute, and Kaiser Permanente of Northern California. Such diversity in focus and in locafion requires a strong administrafive and organizafional structure to successfully promote synergy between the programmafic elements. The Administrative Core will facilitate the overall organizational structure and administrafive activities of the Center, interface with NIH NIAID staff, foster cooperafion between projects and cores, encourage crificism and advice from its scientists, promote fiscal responsibility, and provide a flexible administrative structure to assure the confinued excellence of the Center and its ability to address the Specific Aims. Specifically, the Administrative Core will: (1) provide an organizafional and programmatic structure to promote scientific interactions; (2) provide oversight and planning, set priorities, and establish decisionmaking processes; and (3) ensure that the Center meets all criteria of the multi-project Cooperative Agreement (U19) grant mechanism.

湾区丙型肝炎COOPERAFIVE研究中心（湾区HCV中心）将使用Cutfing-Edge 免疫技术在设计精良且多样化的回顾性病例对照的背景下 Prospecfive临床人群研究人类对HCV的免疫反应。我们想问一个问题： 为什么有些人对护理标准疗法反应良好，而有些则反应呢？为了解决这个问题，该中心将组建一个强大的Mulfidodioldariary团队，由与加利福尼亚大学旧金山大学（旧金山总医院，UC医疗中心和旧金山退伍军人事务中心）相关的三个不同地点组成，该地点是加利福尼亚州Pacific Medical Center，California Paciofic Medical Center，Flood Systems Research Institute和Kacyeria northeria。这种重点和位置的多样性需要强大 行政管理和组织过程结构，以成功促进gromonmafe之间的协同作用 元素。 行政核心将促进中心的整体组织结构和行政活动，与NIH NIAID员工的交互，促进项目和核心之间的合作，鼓励其科学家的克制和建议，促进财政责任，并提供灵活的行政结构，以确保该中心的杰出卓越及其解决特定目标的能力。 具体而言，行政核心将：（1）为组织和编程结构提供 促进科学互动； （2）提供监督和计划，设定优先级并建立决策过程； （3）确保中心符合多项目合作协议（U19）赠款机制的所有标准。