OTHER FUNCTIONS - R&D - HISPANIC COMMUNITY HEALTH STUDY

其他功能-R

• 批准号: 8564653
• 负责人: JAIWEN CAI
• 金额: $ 14.42万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8564653
• 关键词: Award; Bar Codes; Biological; Code; Consent; Contractor; Contracts; Country; DNA; Data; Data Quality; Event; Fee-for-Service Plans; Funding; Genes; Genetic Research; Genotype; Hispanics; Latino; Manuals; National Heart, Lung, and Blood Institute; Participant; Phenotype; Proteomics; Research; Sampling; Serum; Shipping; Ships; Translations; Tube; Update; community health study; design; genetic analysis; genome wide association study; metabolomics; operation; programs; research and development; research study; sex; symposium

Genome-wide association (GWA), genotyping and gene-sequencing studies (Contract Mod) The Omics in Latinos (OLa) initiative is a separate NHLBI 3-year program that has been designed to provide fee-for-service for genotyping (Year 1), genetic analyses (Years 1-3) and fee-for-service sequencing (Year 3) studies using stored DNA from HCHS-SOL participants who consented to allow the use of their DNA for genetic research studies. Three contracts will be awarded, and contract activities are expected to start in 2012. HCHS-SOL may also be invited to participate in NHLBI-directed initiatives involving metabolomics and proteomics research. During the current HCHS-SOL contract period (which ends on March 31, 2013), OLa will provide funding to the HCHS-SOL Coordinating Center for plating DNA samples and de-identified participant IDs to the OLa genotyping contract awardee, and transfer of phenotype and event data to the genetic analysis contractor.

全基因组关联 (GWA)、基因分型和基因测序研究 (Contract Mod) 拉丁裔组学 (OLa) 计划是一项独立的 NHLBI 3 年计划，旨在为基因分型（第 1 年）、遗传分析（第 1-3 年）和按服务收费测序（第 1 年）提供收费服务。第 3 年）使用来自 HCHS-SOL 参与者的储存 DNA 进行研究，这些参与者同意使用他们的 DNA 进行基因研究。将授予三份合同，合同活动预计将于 2012 年开始。HCHS-SOL 也可能被邀请参加 NHLBI 指导的涉及代谢组学和蛋白质组学研究的计划。 在当前的 HCHS-SOL 合同期内（截至 2013 年 3 月 31 日），OLa 将向 HCHS-SOL 协调中心提供资金，用于将 DNA 样本和去识别化的参与者 ID 电镀给 OLa 基因分型合同获奖者，并转移表型和事件数据给遗传分析承包商。