Training Program in Transplantation
移植培训计划
基本信息
- 批准号:8500419
- 负责人:
- 金额:$ 9.44万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2004
- 资助国家:美国
- 起止时间:2004-04-01 至 2015-07-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
DESCRIPTION (provided by applicant): This is a resubmission of a competing renewal for a highly successful training program in transplantation immunology and stem cell biology. Over the past 11 years, a dynamic group of internationally recognized investigators in transplantation and stem cell biology were strategically recruited to the University of Louisville which is increasingly recognized for its comprehensive translational research in composite tissue allotransplantation, tolerance, and stem cell-mediated regenerative medicine. This training program directly addresses the mission of the NIH training grant program to help ensure that a diverse and highly trained workforce is available to assume leadership roles related to the nation's biomedical research agenda. All positions have been filled with outstanding applicants to date including six women (one minority), thereby addressing the major concern of all three reviewers. Applicants must have a Ph.D., D.V.M., or M.D. They are required to submit a CV, publication list, three letters of recommendation, and a statement of the specific research proposed. An Executive Training Committee comprised of the program Director and senior trainers selects the trainees. Trainees assemble a program and undertake basic research with one trainer and one or more co-mentors. Evaluation of the Training Program occurs on several levels, including manuscript and abstract submissions; oral presentations and participation at research seminar series; and completion and submission of an NRSA postdoctoral individual training grant or equivalent (AHA, JDRF, ASH, or other foundation or society fellowships) within the second year of training. The overall progress of this Training Program is assessed by an External Advisory Board through semiannual meetings and feedback. The External Advisory Board also assists in minority recruitment. The faculty in this training program has the expertise and breadth of background to successfully train fellows in well-equipped, centrally-located laboratories, it is our goal that our trainees will be qualified to assume leadership positions related to transplantation and stem cell biology in industry, academia, and biotechnology. Our established track record demonstrates that we are well on our way to achieving this goal.
描述(由申请人提供):这是针对移植免疫学和干细胞生物学的非常成功的培训计划的竞争更新的重新提交。在过去的11年中,一组国际公认的移植和干细胞生物学研究者被战略性地招募到路易斯维尔大学(University of Louisville),该研究人员因其在复合组织中的全面转化研究同种异体移植,耐受性,耐受性和干细胞介导的再生性再生药物方面而越来越认可。该培训计划直接介绍了NIH培训赠款计划的使命,以帮助确保有多样化且训练有素的劳动力可以担任与国家生物医学研究议程相关的领导角色。迄今为止,所有职位都充满了杰出的申请人,其中包括六名妇女(一名少数),从而解决了所有三位审稿人的主要关注点。申请人必须拥有博士学位,D.V.M.或M.D.他们必须提交简历,出版清单,三份推荐信以及提议的具体研究声明。由计划主任和高级培训师组成的执行培训委员会选择学员。学员组成了一项计划,并与一位或一名或多个院长进行基础研究。对培训计划的评估发生在多个层次上,包括手稿和抽象提交;口头演讲和参与研究研讨会系列;在培训的第二年内,完成并提交了NRSA博士后个人培训补助金或同等学历(AHA,JDRF,ASH或其他基金会或社会奖学金)。该培训计划的总体进展是由外部顾问委员会通过半年度会议和反馈评估的。外部顾问委员会还协助少数民族招募。该培训计划中的教职员工具有成功培训培训的专业知识和广度,可以在设备齐全的集中实验室中培训研究员,我们的目标是,我们的学员将有资格担任与行业,学术界和生物技术的移植和干细胞生物学有关的领导职位。我们既定的记录都表明,我们正在实现这一目标。
项目成果
期刊论文数量(3)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Immunomodulation with SA-FasL protein as an effective means of preventing islet allograft rejection in chemically diabetic NOD mice.
- DOI:10.1016/j.transproceed.2013.01.041
- 发表时间:2013-06
- 期刊:
- 影响因子:0.9
- 作者:Yolcu, E. S.;Zhao, H.;Shirwan, H.
- 通讯作者:Shirwan, H.
Posttransplantation systemic immunomodulation with SA-FasL-engineered donor splenocytes has robust efficacy in preventing cardiac allograft rejection in mice.
使用 SA-FasL 改造的供体脾细胞进行移植后全身免疫调节在预防小鼠心脏同种异体移植排斥方面具有强大的功效。
- DOI:10.1016/j.transproceed.2013.01.049
- 发表时间:2013
- 期刊:
- 影响因子:0.9
- 作者:Zhao,H;Woodward,KB;Shirwan,H;Grimany-Nuno,O;Yolcu,ES
- 通讯作者:Yolcu,ES
Evidence that FoxP3+ regulatory T cells may play a role in promoting long-term acceptance of composite tissue allotransplants.
- DOI:10.1097/tp.0b013e31820fafb4
- 发表时间:2011-04-27
- 期刊:
- 影响因子:6.2
- 作者:Bozulic LD;Wen Y;Xu H;Ildstad ST
- 通讯作者:Ildstad ST
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{{ truncateString('SUZANNE T ILDSTAD', 18)}}的其他基金
Delayed Tolerance Induction in Living Related Donor Renal Transplant Recipients
与生活相关的供体肾移植受者的延迟耐受诱导
- 批准号:
8252790 - 财政年份:2012
- 资助金额:
$ 9.44万 - 项目类别:
AMD-FCRx to Restore Damaged Pigment Epithelium
AMD-FCRx 可恢复受损的色素上皮
- 批准号:
6991727 - 财政年份:2005
- 资助金额:
$ 9.44万 - 项目类别:
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