2013 Matrix Metalloproteinase Gordon Research Conference and Gordon Research Semi

2013年基质金属蛋白酶戈登研究会议及戈登研究半会

• 批准号: 8511050
• 负责人: SUNEEL S APTE
• 金额: $ 0.6万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8511050
• 关键词: Academia; Area; Arthritis; Cardiovascular system; Collaborations; Communities; Connective Tissue Diseases; Data; Disease; Disease Pathway; Disintegrins; Disseminated Malignant Neoplasm; Drug Industry; Ensure; Enzymes; Equilibrium; Extracellular Matrix; Family; Fostering; Future; Gender; Goals; Government; Health; Human; Immersion Investigative Technique; Industry; Inflammatory; International; Italy; Knowledge; Lung; Malignant Neoplasms; Matrix Metalloproteinases; Medical; Mentors; Metalloproteases; Mission; Molecular; Neurologic; Participant; Pathway interactions; Peptide Hydrolases; Research; Research Personnel; Research Project Grants; Resort; Resource Sharing; Scientific Advances and Accomplishments; Scientist; Time; Translational Research; Work; abstracting; astacin; base; career; design; experience; fundamental research; improved; inhibitor/antagonist; innovation; interest; meetings; multidisciplinary; next generation; novel; peer; posters; programs; public health relevance; racial and ethnic; success; symposium

DESCRIPTION (provided by applicant): The Gordon Research Conference (GRC) on Matrix Metalloproteinases (MMPs) (the MMP-GRC) is the premier meeting in a scientific field of exceptional importance for cancer, metastatic disease, connective tissue disorders such as arthritis, and numerous inflammatory, lung, cardiovascular and neurological conditions. The conference spans the full spectrum of fundamental and translational research on disease-relevant metalloproteinases that share catalytic and regulatory mechanisms, i.e., MMP, ADAM (a disintegrin and metalloproteinase), ADAMTS (ADAM with thrombospondin motifs) and astacin-like proteases, and their inhibitors. The 2013 MMP-GRC will be held at the Il Ciocco Tuscany Resort, Barga, Tuscany, Italy, from May 19-24, 2013 and is conjoined with a Gordon-Kenan Research Seminar (MMP-GRS) (May 18-19, 2013). The 2013 MMP-GRC and MMP-GRS are residential conferences, a tradition that has consistently led to the success of previous MMP-GRCs. The MMP-GRC and MMP-GRS provide an unparalleled forum for intermingling of trainees with established investigators. The residential format of the conference promotes close interactions, collaborations, and a sense of community in the participating scientists, who are drawn from academia, pharmaceutical industry and government sectors from around the world. The mission of the MMP- GRC and MMP-GRS is to advance scientific innovation with free exchange of ideas, to facilitate collaborations, and to nurture the next generation of scientists i the field, all with the ultimate goal of promoting human health. The 2013 MMP-GRC and MMP-GRS have a major disease focus on cancer, and an innovative thematic emphasis on metalloproteinases as integral components of molecular networks and disease pathways. The conference comprises 9 sessions that emphasize presentation of unpublished data and offer abundant time for discussion, with additional free time available for informal interactions. Sessions are chaired by experienced scientists, who are drawn from within the metalloproteinase community for their expertise, diversity and stature in the field. The international slate of speakers achieves a gender balance and representative cross-section of ethnic/racial diversity and includes numerous early-career investigators. Community renewal is emphasized by ensuring that the majority of invited speakers have not spoken before at a MMP-GRC. The conference program gives equal emphasis to fundamental and translational science. Each fundamental session is highly relevant to understanding cancer pathways, and there is an additional strong emphasis on extracellular matrix, which is relevant not only to cancer stroma, but also to connective tissue disease. Participants are selected based on their interest in and current activities relevant to the field, and on submitted abstracts of their ongoing work. A third of the conference platform presentations will be selected from the abstracts with two poster sessions allowing abundant time for discussion. We expect the conference to stimulate and inspire, and to set new goals and directions for cutting-edge research for the near future.

描述（由申请人提供）：关于基质金属蛋白酶（MMPS）（MMP-GRC）的戈登研究会议（GRC）是在科学领域中对癌症，转移性疾病，结缔组织疾病（如关节炎，诸如关节炎）以及诸如关节炎以及多种炎症，肺，心血管疾病和多种炎症的科学重要性领域的主要会议。会议涵盖了有关疾病与疾病相关的金属蛋白酶的全部基础和转化研究，这些蛋白酶具有催化和调节机制，即MMP，ADAM，ADAM（一种分解蛋白和金属蛋白酶），ADAMTS（ADAM，ADAM，具有血小板蛋白基序）和类似抗氧蛋白的蛋白质和类似于蛋白质的蛋白酶和蛋白酶。 2013年MMP-GRC将于2013年5月19日至24日在意大利托斯卡纳市的IL Ciocco托斯卡纳度假村举行，并与Gordon-Kenan研究研讨会（MMP-GRS）结合（2013年5月18日至19日）。 2013年的MMP-GRC和MMP-GR是住宅会议，这种传统一直在导致以前的MMP-GRC成功。 MMP-GRC和MMP-GRS提供了一个无与伦比的论坛，用于与既定的调查员交织在一起。会议的住宅格式促进了参与科学家的紧密互动，合作和社区意识，这些科学家是从世界各地的学术界，制药行业和政府部门吸引的。 MMP-GRC和MMP-GRS的使命是通过自由交流思想来推进科学创新，促进合作，并培养下一代科学家I该领域，所有这些都是促进人类健康的最终目标。 2013年的MMP-GRC和MMP-GRS对癌症有主要疾病的重点，并且具有创新的主题重点是金属蛋白酶作为分子网络和疾病途径不可或缺的成分。该会议包括9次会议，强调展示未发表的数据，并为讨论提供丰富的时间，并提供额外的空闲时间进行非正式互动。会议由经验丰富的科学家主持，他们的专业知识，多样性和地位在现场的专业知识，多样性和身材中被吸引。国际演讲者实现了性别平衡和种族/种族多样性的代表性横截面，其中包括众多早期职业调查员。通过确保大多数被邀请的演讲者在MMP-GRC之前没有讲话来强调社区更新。会议计划同等重要的是基本和转化科学。每个基本课程都与了解癌症途径高度相关，并且对细胞外基质有一个额外的强调，这不仅与癌症基质有关，而且与结缔组织疾病有关。根据与该领域相关的兴趣和当前活动的兴趣以及提交其正在进行的工作的摘要，选择了参与者。第三 会议平台演示文稿中将从摘要中选出两个海报会议，以便大量的讨论时间。我们希望会议能够刺激和激发灵感，并为在不久的将来设定新的目标和方向。