Neurobehavioral Contributors to Math Failure: A Reward-Based Learning Framework

数学失败的神经行为因素：基于奖励的学习框架

基本信息

批准号：
8554790
负责人：
TERRY L. JERNIGAN
金额：
$ 52.95万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-09-28 至 2016-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8554790
关键词：
12 year old Accounting Achievement Address Affect Affective Animals Anisotropy Anxiety Architecture Area Association Learning Attention Behavioral Brain Child Childhood Choice Behavior Clinical Cognition Cognitive Complement Complex Data Development Discipline Emotional Emotions Ensure Exposure to Failure Genetic Genotype Grant Growth Human Image Individual Individual Differences Knowledge Learning Learning Disabilities Literature Longitudinal Studies Machine Learning Mathematics Measures Mentors Methods Modeling Neurocognition Neurocognitive Outcome Parietal Patient Self-Report Pediatric Research Perception Perceptual learning Phenotype Play Prefrontal Cortex Psychological reinforcement Relative (related person)Research Research Infrastructure Research Personnel Research Project Grants Resources Rewards Risk Role School-Age Population Scientist Statistical Methods Stimulus Surface System Time Work base classical conditioning computational neuroscience data sharing elementary school emotional factor experience genome-wide graduate student high risk imaging modality intraparietal sulcus mathematical model neurobehavioral neuroimaging novel preference programs prospective relating to nervous system response reward processing skills

项目摘要

DESCRIPTION (provided by applicant): In this set of applications, we propose to initiate a new Learning Disabilities Research Hub focusing initially on high risk for mathematics failure. We proposed to situate this new Hub within an existing strong infrastructure for pediatric neurobehavioral and imaging research, the Pediatric Neurocognition, Imaging, and Genetics (PING) data resource. PING infrastructure provides many important advantages for building a new cross disciplinary and multiple-investigator program, as it has already brought together a strong team of behavioral, clinical, imaging, computational, and genetics investigators as a closely integrated team, and most importantly has attracted a very talented group of young investigators and graduate students focused on the problems addressed in the proposed research. A unifying theme of the studies that our team has proposed is the notion that math failure, and perhaps academic failure more broadly, emerges gradually through interactions of putative early conceptual weaknesses, attributable in some cases to poor functioning and anomalous neural architecture in specific neural systems, with increasing reward-based biases that contribute, additively or non-additively, to suppression of the normal learning trajectory. Consistent with this theme we refer to our proposed research hub as the Roles of Emotion and Choice (REaCh) in Learning Disabilities Research Hub (LDRH). The proposed REaCh Hub has 3 components: a new research project to investigate key questions about learning and the neural architecture during early development in children at high risk for math failure, and two cores. The Administrative Core proposal describes the management plan for the new Hub and the PING infrastructure that will be adapted for the new studies; and focuses on a nested mentoring plan for ensuring close interaction between trainees at different levels with mid-level and senior investigators within focused workgroups. The assets of the Core for within-Hub and extra-Hub data sharing are also described. A Developmental Infrastructure Core proposal describes the administration of a small grant program to support novel work within the Hub by junior investigators, trainees, and investigators from disciplines outside of the original REaCh LDRH group.

描述（由申请人提供）：在这组应用程序中，我们建议启动新的学习障碍研究中心，最初着重于数学失败的高风险。我们提议将这个新的枢纽放置在现有的针对小儿神经行为和成像研究，小儿神经认知，成像和遗传学（PING）数据资源的强大基础设施中。 PING基础架构为建立一个新的跨学科和多重评估程序提供了许多重要的优势，因为它已经汇集了一组强大的行为，临床，成像，计算，计算和遗传学研究者的团队，并作为一个紧密整合的团队，并且最重要的是吸引了最重要的团队。一群很有才华的年轻研究人员和研究生集中在拟议的研究中所解决的问题上。我们团队提出的研究的一个统一主题是，数学失败，也许更广泛地通过假定的早期概念性弱点的互动来逐渐出现，在某些情况下可以归因于特定神经系统的功能差和异常神经体系结构，随着基于奖励的偏见增加，在抑制正常学习轨迹上造成了贡献或非添加性的贡献。与这个主题一致，我们将我们提出的研究中心称为学习障碍研究中心（LDRH）中情感和选择（触及）的作用。拟议的REACH HUB有3个组成部分：一个新的研究项目，旨在调查有关学习和早期发育期间的神经建筑的关键问题，这些儿童患有数学失败的高风险和两个核心。行政核心建议描述了将适用于新研究的新枢纽和PING基础设施的管理计划；并专注于一项嵌套的指导计划，以确保与中级工作组中的中级和高级调查员在不同级别的学员之间进行密切相互作用。还描述了内置核心和额外中心数据共享的核心资产。一项发展基础设施核心提案描述了一项小型赠款计划的管理，以支持来自原始Reach LDRH组以外学科的初级调查人员，受训人员和研究人员在中心内的新工作。