Breast Oncology

乳腺肿瘤学

• 批准号: 8710509
• 负责人: FRANK PATRICK MCCORMICK
• 金额: $ 7.49万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-06-01 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8710509
• 关键词: Area; Basic Science; Bioinformatics; Biological; Biology; Breast; Budgets; California; Cancer Center Support Grant; Clinical Research; Clinical Trials; Communities; Companions; Diagnostic; Discipline; Disease; Early Diagnosis; Environment; Epidemiology; Etiology; Funding; Genetic; Goals; Grant; Health; Individual; Intervention; Joints; Laboratories; Malignant Neoplasms; Methods; Modeling; Morbidity - disease rate; Oncology; Outcome; Patients; Peer Review; Physicians; Population Research; Publications; Radiation Oncology; Research; Research Infrastructure; Research Personnel; Risk; Science; Series; Site; System; Testing; Therapy Clinical Trials; Translations; Universities; Work; base; cancer prevention; care delivery; clinical care; improved; innovation; malignant breast neoplasm; meetings; member; mortality; multidisciplinary; new therapeutic target; novel; oncology program; outreach; programs; tumor; tumor progression

The Breast Oncology Program (Program) is comprised of 39 Program Members from 13 different UCSF departments. The Program supports and stimulates basic, clinical, and population research in breast cancer and facilitates the translation of these findings into improved cancer management and control. The Program's themes are as follows: (1) epidemiology and etiology; (2) cancer prevention, risk models, and early detection; (3) genetics and biology of cancer progression; (4) new therapeutic targets and approaches; and (5) outreach, clinical care delivery, and outcomes. Research in the Program is supported by the Bay Area Breast Cancer SPORE, eight large multi-disciplinary, multi-institutional projects that support work in one or more themes, a multi-campus University of California Office of the President sponsored ATHENA Breast Health Network integrating clinical care and research by numerous individual investigator-initiated grants. Since the last competitive renewal much effort has been dedicated towards investigator initiated therapeutic trials, innovative companion diagnostic clinical trials, testing new radiation oncology treatment delivery systems including correlative science, as well as establishing a CLIA-compliant testing laboratory and an integrative bioinformatics and IT infrastructure. The Program has become more cohesive, has a high level of interaction that has led to new grant funding with joint program and project leaders and co-investigators across disciplines. Interactions between Program members are encouraged in several discussion forums, including a weekly multidisciplinary seminar, an annual retreat, a weekly tumor board, a bi-weekly breast site study review meeting, a monthly community forum, and a patient-physician management discussion series. The Program has $22,189,900 total peer-reviewed support for the last budget year. The Program has 17% intra-programmatic and 17% inter-programmatic publications.

乳房肿瘤计划（计划）由来自13个不同UCSF部门的39名计划成员组成。该计划支持并刺激乳腺癌中的基本，临床和人群研究，并促进这些发现将这些发现转化为改善的癌症管理和控制。该计划的主题如下：（1）流行病学和病因； （2）预防癌症，风险模型和早期检测； （3）癌症进展的遗传学和生物学； （4）新的治疗靶和方法； （5）外展，临床护理提供和结果。该计划中的研究得到了湾区乳腺癌孢子的支持，八个大型多学科的多机构项目，这些项目支持一个或多个主题的工作，这是一个多个校长的总统大学赞助的Athena乳房健康网络，整合了临床护理和许多个人研究人员促成的格局。 自从上次竞争性更新以来，已经为研究者启动了治疗试验，创新的伴侣诊断临床试验，测试包括相关科学在内的新的放射肿瘤治疗输送系统以及建立CLIA符合性测试实验室以及集成生物信息和IT基金结构的新型辐射肿瘤治疗系统。该计划变得更加凝聚力，具有高水平的互动，这导致了与联合计划以及跨学科的项目负责人和共同投资者的新资助。在几个讨论论坛上鼓励计划成员之间的互动，包括每周的多学科研讨会，年度务虚会，每周肿瘤委员会，每两周一次的乳房网站研究审查会议，每月社区论坛和患者 - 医学管理讨论系列。该计划对上一年的预算年有22,189,900美元的同行评审支持。该计划具有17％的概括性内部图表和17％的程序间出版物。