Principal Research Core

主要研究核心

• 批准号: 8320785
• 负责人: JAMES R. MCKAY
• 金额: $ 11.36万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8320785
• 关键词: Acute; Address; Alcohol consumption; Alcohol dependence; Alcohols; Algorithms; Applications Grants; Archives; Caring; Communities; Data; Data Analyses; Data Collection; Development; Drops; Evaluation; Foundations; Funding; Intake; Intervention; Lead; Link; Manuals; Minnesota; Mission; Modeling; Modification; Monitor; National Institute on Alcohol Abuse and Alcoholism; Online Systems; Outcome; Patient Preferences; Patients; Pharmacotherapy; Primary Health Care; Procedures; Provider; Psychosocial Assessment and Care; Randomized; Research; Research Infrastructure; Research Personnel; Residential Treatment; Resources; Services; System; Telephone; Testing; alcohol abuse therapy; alcoholism therapy; base; data management; design; evidence base; innovation; medical specialties; programs

In the Principal Research Core (PRC), the Developmental Projects address issues at specific points in our conceptual model (see Projects 1-3 in Figure 1). Project 1 is focused on whether access to and engagement in evidence-based alcohol treatment for primary care patients with alcohol dependence can be increased through the use of a nonspecialty care approach, and consideration of patient preference and modifications to treatment for nonresponders. This model, referred to as Alcohol Care Management, includes telephone- based assessment and monitoring, pharmacotherapy, and psychosocial support. Therefore, Project 1 addresses the links in our conceptual model between identification in primary care, initial engagement, and acute care. Project 2, on the other hand, is focused on increasing engagement and retention in patients who undergo an intake evaluation in a specialty care program. This project will determine whether offering patients who fail to engage in specialty care the choice of several alternative approaches produces higher rates of engagement and continued participation than further efforts to engage them in specialty care only. This project will also test a telephone-based procedure for re-engaging patients who achieved initial engagement in specialty care but subsequently dropped out. Both projects will also examine whether the experimental conditions lead to better short-term alcohol use outcomes, in addition to better engagement and retention. Moreover, both projects now feature sequential randomizations designs, which are recommended by Murphy et al. (2007) for the development of adaptive algorithms. Project 3 is an initial evaluation of the feasibility and utilization of a highly innovative, web-based adaptive continuing care program developed by the Hazelden Foundation, a premier non-profit provider of residential treatment in Minnesota.

在主要研究核心（PRC）中，发展项目解决了特定点的问题 我们的概念模型（参见图 1 中的项目 1-3）。项目 1 的重点是是否能够访问和参与 可以增加对酒精依赖的初级保健患者的循证酒精治疗 通过使用非专业护理方法，并考虑患者的偏好和修改 对无反应者进行治疗。该模型称为酒精护理管理，包括电话 基于评估和监测、药物治疗和社会心理支持。因此，项目1 解决了我们的概念模型中初级保健中的识别、初始参与和 急性护理。另一方面，项目 2 的重点是提高以下患者的参与度和保留率： 接受专业护理计划的摄入评估。该项目将决定是否为患者提供 对于未能接受专业护理的人来说，选择几种替代方法会产生更高的治愈率 参与和持续参与，而不是进一步努力让他们仅参与特殊护理。这个项目 还将测试基于电话的程序，以重新吸引已初步参与专业治疗的患者 照顾，但随后退学。这两个项目还将检查实验条件是否 除了更好的参与度和保留度之外，还能带来更好的短期饮酒结果。而且， 这两个项目现在都采用顺序随机化设计，这是 Murphy 等人推荐的。 (2007) 用于开发自适应算法。项目3是对可行性和利用的初步评估 由 Hazelden 基金会开发的高度创新、基于网络的适应性持续护理计划 明尼苏达州首屈一指的非营利性住院治疗提供商。